Protein Alignment CG4467 and pepN

DIOPT Version :10

• Sequence 1: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Sequence 2: NP_415452.1
• Gene: pepN / 947253
• ECOCYCID: EG10696
• Length: 870
• Species: Escherichia coli
• Alignment Length: 986
• Identity: 192/986 - (19%)
• Similarity: 311/986 - (31%)
• Gaps: 360/986 - (36%)

  Fly   157 TLDVKGQVTIDLHVE----------------KETNFIVLHIQDLNVT-----EKAIVTPG-PKGY 199
            |.|:..|.|:...|.                ::...:.:||.|...|     |.|:|... |:.:
E. coli    26 TFDLDAQKTVVTAVSQAVRHGASDAPLRLNGEDLKLVSVHINDEPWTAWKEEEGALVISNLPERF 90

  Fly   200 ALKIVKVLEFPPRQQLYIEVKERLKKKSNYTLNLRWYSKLNPEPEGFYVDQYESSNGVERLLAAT 264
            .|||:.  |..|                          ..|...||.    |:|.:.:     .|
E. coli    91 TLKIIN--EISP--------------------------AANTALEGL----YQSGDAL-----CT 118

  Fly   265 VFRPNGARRAFPCFDEPHVRAPFRISVFRD--RFHIGLSNSIVHTTEDVGFYMGTGLL------- 320
            .....|.|......|.|.|.|.|...:..|  ::...|||         |..:..|.|
E. coli   119 QCEAEGFRHITYYLDRPDVLARFTTKIIADKIKYPFLLSN---------GNRVAQGELENGRHWV 174

  Fly   321 --RDDFIETPPLPADAVAWVVSDFQRESLQPSAAYIPTTPAPPGSGVGGKKSAQLNNYTQLKGKN 383
              :|.|    |.|....|.|..||.
E. coli   175 QWQDPF----PKPCYLFALVAGDFD---------------------------------------- 195

  Fly   384 PPVRNITALTHSLNVNLTPRQNLTVVQPTTTTAWPVNLNGNGKPSNLTSLSQSTGSSIKRAPSYT 448
                                    |::.|.||.       :|:...| .|....| ::.|||
E. coli   196 ------------------------VLRDTFTTR-------SGREVAL-ELYVDRG-NLDRAP--- 224

  Fly   449 FYAPRDLLIRSSFILHTSRDVLEYLQTWLDISYPLTKVDFVALPSLDRNMISSLGLVTLKTSF-L 512
             :|...|  ::|......|..|||   .||| |.:..|||..:.:::..     ||....:.: |
E. coli   225 -WAMTSL--KNSMKWDEERFGLEY---DLDI-YMIVAVDFFNMGAMENK-----GLNIFNSKYVL 277

  Fly   513 TDPSSITSEQYQFSALRIAEAMVRQFFGGITSRKVLKDVW----LWEGLIQY--------LGIHA 565
            ....:.|.:.|    |.|...:..::|...|..:|....|    |.|||..:        ||..|
E. coli   278 ARTDTATDKDY----LDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDLGSRA 338

  Fly   566 LAPLQETWPLREMYLLKMATAALDIDAIQGWDSIMNGTSHDGNNEEFFV----QKTAAIFSMLHT 626
            :..:..   :|.|..|:.|.     ||......|......:.||  |:.    :|.|.:..|:||
E. coli   339 VNRINN---VRTMRGLQFAE-----DASPMAHPIRPDMVIEMNN--FYTLTVYEKGAEVIRMIHT 393

  Fly   627 AIGEDRFRGCLGSFLKVNRFRTAEPTDLWTICTKKANGSKNIKDM--MTLWTHQPGFPLLTVTKM 689
            .:||:.|:..:..:.:.:....|...|.    .:....:.|: |:  ...|..|.|.|::||...
E. coli   394 LLGEENFQKGMQLYFERHDGSAATCDDF----VQAMEDASNV-DLSHFRRWYSQSGTPIVTVKDD 453

  Fly   690 GN------SISISQR-PFRP--AEFLAIHDDSYDGNNYNKTTLNATDMPSTVATTTQGSKHKVAP 745
            .|      :::|||| |..|  ||...:|                  :|  .|.....::.||.|
E. coli   454 YNPETEQYTLTISQRTPATPDQAEKQPLH------------------IP--FAIELYDNEGKVIP 498

  Fly   746 HMKWIFPVTYVTDINNVSETLWMQNVDVTFNVPENVKWIKVNAIQNGYYRVVYNDDNWASLIEEL 810
            ..|...||..|.::....:|....||                     |::.|      .:|:.|.
E. coli   499 LQKGGHPVNSVLNVTQAEQTFVFDNV---------------------YFQPV------PALLCEF 536

  Fly   811 AANPNRFT---SEDRLGMLSDAFTLCHA-----------NLLPCEITMNMIQYLPSETHYGPMAL 861
            :| |.:..   |:.:|     .|.:.||           :||...|.:|:.::...:    |::|
E. coli   537 SA-PVKLEYKWSDQQL-----TFLMRHARNDFSRWDAAQSLLATYIKLNVARHQQGQ----PLSL 591

  Fly   862 ALRHLEKWRRILKYSEC-------FLMLSEFIKM-KISTVMEKVGWSDDGDVATRLLRPEV---L 915
            .:...:.:|.:|...:.       .|.|....:| ::..:::.:..::..:..||.|..|:   |
E. coli   592 PVHVADAFRAVLLDEKIDPALAAEILTLPSVNEMAELFDIIDPIAIAEVREALTRTLATELADEL 656

  Fly   916 LA----------SVLWEDIDSITKAKNMLNQYLYYNGTAIPPNLREVVYTGSILSGEYIYWQHCW 970
            ||          .|..|||...| .:|...::|.:..|    :|.:|:
E. coli   657 LAIYNANYQSEYRVEHEDIAKRT-LRNACLRFLAFGET----HLADVL----------------- 699

  Fly   971 ERFVNLQRTSETFVERMQLLRALGRTK------------------DAWLQNRLL--SHVTMLPTE 1015
                    .|:.|.|...:..||....                  |.|.||.|:  ....:..|.
E. coli   700 --------VSKQFHEANNMTDALAALSAAVAAQLPCRDALMQEYDDKWHQNGLVMDKWFILQATS 756

  Fly  1016 EVVQVLKAIAG 1026
            ....||:.:.|
E. coli   757 PAANVLETVRG 767

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4467	NP_001036747.1	GluZincin	145..677	CDD:472708	112/571 (20%)
		ERAP1_C	783..1078	CDD:463368	53/299 (18%)
pepN	NP_415452.1	pepN	1..870	CDD:237585	192/986 (19%)