Protein Alignment CG4467 and APM1

DIOPT Version :10

• Sequence 1: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Sequence 2: NP_195035.2
• Gene: APM1 / 829446
• AraportID: AT4G33090
• Length: 879
• Species: Arabidopsis thaliana
• Alignment Length: 1033
• Identity: 235/1033 - (22%)
• Similarity: 387/1033 - (37%)
• Gaps: 232/1033 - (22%)

  Fly   128 GEPFPWLEKMLPTSVRPLRYMVTIHPNLTTLDVKGQVTIDLHVEKETNFIVLHIQDLNVTEKAI- 191
            |||      .||....|.||.:.::|:|......|.|.|||.:..:|.||||:..||:|.:.::
plant     6 GEP------RLPKFAVPKRYDLRLNPDLIACTFTGTVAIDLDIVADTRFIVLNAADLSVNDASVS 64

  Fly   192 VTPGPKGYALKIVKVLEFPPRQQLYIEVKERLKKKSNYTLNLRWYSKLNPEPEGFYVDQYESSNG 256
            .||.....||...||:.|...:.|.:|..|.|..... .|.|.:...||.:.:|||...|| .||
plant    65 FTPPSSSKALAAPKVVLFEEDEILVLEFGEILPHGVG-VLKLGFNGVLNDKMKGFYRSTYE-HNG 127

  Fly   257 VERLLAATVFRPNGARRAFPCFDEPHVRAPFRISVFRDRFHIGLSNSIVHTTEDVGFYMGTGLLR 321
            .::.:|.|.|.|..|||.|||:|||..:|.|:|
plant   128 EKKNMAVTQFEPADARRCFPCWDEPACKATFKI-------------------------------- 160

  Fly   322 DDFIETPPLPADAVAWVVSDFQRESLQPSAAYIPTTPAPPGSGVGGKKSAQLNNYTQLKGKNPPV 386
                 |..:|.|.||                                                 :
plant   161 -----TLEVPTDLVA-------------------------------------------------L 171

  Fly   387 RNITALTHSLNVNL-------TPRQNLTVVQPTTTTAWPVNLNGNGKPSNLTSLSQSTGSSIKRA 444
            .|:..:...:|.||       :|      :..|...|..|.|        ...:...|...||
plant   172 SNMPIMEEKVNGNLKIVSYQESP------IMSTYLVAIVVGL--------FDYVEDHTSDGIK-- 220

  Fly   445 PSYTFYAPRDLLIRSSFILHTSRDVLEYLQTWLDISYPLTKVDFVALPSLDRNMISSLGLVTLK- 508
              ...|.......:..|.||.....|:..:.:..:.|||.|:|.:|:|......:.:.||||.:
plant   221 --VRVYCQVGKADQGKFALHVGAKTLDLFKEYFAVPYPLPKMDMIAIPDFAAGAMENYGLVTYRE 283

  Fly   509 TSFLTDPSSITSEQYQFSALRIAEAMVRQFFGGITSRKVLKDVWLWEGL---IQYLGIHALAPLQ 570
            |:.|.|.....:...|..|..:|..:..|:||.:.:.:....:||.||.   :.||...:|.|..
plant   284 TALLYDEQHSAASNKQRVATVVAHELAHQWFGNLVTMEWWTHLWLNEGFATWVSYLATDSLFPEW 348

  Fly   571 ETWPLREMYLLKMATAALDIDAIQGWDSIMNGTSHDGNNEEFF----VQKTAAIFSMLHTAIGED 631
            :.|    ...|..:|..|.:|.::....|....:|....:|.|    .:|.|::..||.:.:|.:
plant   349 KIW----TQFLDESTEGLRLDGLEESHPIEVEVNHAAEIDEIFDAISYRKGASVIRMLQSYLGAE 409

  Fly   632 RFRGCLGSFLKVNRFRTAEPTDLWTICTKKANGSKNIKDMMTLWTHQPGFPLLTVTKMGNSISIS 696
            .|:..|.:::|.:.:..|:..|||  ...:|...:.:..:|:.||.|.|:|:::.......:.:.
plant   410 VFQKSLAAYIKNHAYSNAKTEDLW--AALEAGSGEPVNKLMSSWTKQKGYPVVSAKIKDGKLELE 472

  Fly   697 QRPFRPAEFLAIHDDSYDGNNYNKTTLNATDMPSTVATTTQGSKHKVAPHMKWIFPVT-----YV 756
            |..|                                  .:.||..:    .:||.|||     |.
plant   473 QSRF----------------------------------LSSGSPGE----GQWIVPVTLCCGSYE 499

  Fly   757 TDIN----------NVSETLWMQNVDVTFNVPENVKWIKVNAIQNGYYRVVYNDDNWASLIEELA 811
            ...|          ::.|.|.....|.:..:.....|||:|..|.|:|||.|:|...|.|  ..|
plant   500 KRKNFLLESKSGAYDLKELLGCSIADGSDKINGTCSWIKINVDQAGFYRVKYDDSLAAGL--RNA 562

  Fly   812 ANPNRFTSEDRLGMLSDAFTLCHANLLPCEITMNMIQYLPSETHYGPMA--LALRHLEKWRRILK 874
            ......||.||.|:|.|:|.|..|........:.:......|..|..::  :|:.:     :::|
plant   563 TESQSLTSIDRYGILDDSFALTMARQQSLASLLTLCSAYKKELDYTVLSNLIAISY-----KVVK 622

  Fly   875 Y-----SECFLMLSEFIKMKISTVMEKVGWS-DDGDV-ATRLLRPEVLLASVLWEDIDSITKAKN 932
            .     .|....:..|..........|:||. ..|:. ...:||.|||.|..::...:::.:|..
plant   623 IGADANQELMSGIKHFFIGVFQFAAGKLGWDPKQGESHLDAMLRGEVLTALAVFGHDETLKEAVR 687

  Fly   933 MLNQYLYYNGT-AIPPNLREVVYTG-------SILSGEYIYWQHCWERFVNLQRTSETFVERMQL 989
            ..:.:|....| .:||::|...|..       |..||        :|..:.:.|.::...|:.::
plant   688 RFDAFLADRNTPLLPPDIRRAAYVAVMQRANKSDKSG--------YESLLRVYRETDLSQEKTRI 744

  Fly   990 LRALGRTKDAWLQNRLLSHVTMLPTEEV--VQVLKAIAGTP-TGGAMACRFLQAKWFELEKRLGP 1051
            |.:|....|..:...:|:.|.   ::||  ...|..::|.. .|..:|.::||.||..:....|.
plant   745 LGSLASCPDPTIVQDVLNFVL---SDEVRNQDALYGLSGVSWEGREVAWKWLQEKWEYIGNTWGS 806

  Fly  1052 GTISFAKVISAITQYGATKFDYDELKSLVHRFGRGHGMSV---LNMTLSSVASNVEWV 1106
            |.: ..:.|||:....|:   :::.|.:...|......|:   |..::..|..|..||
plant   807 GFL-ITRFISAVVSPFAS---FEKAKEVEEFFATRSKPSMARTLKQSIERVHINANWV 860

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4467	NP_001036747.1	GluZincin	145..677	CDD:472708	129/547 (24%)
		ERAP1_C	783..1078	CDD:463368	74/314 (24%)
APM1	NP_195035.2	M1_APN-Q_like	18..453	CDD:341064	129/546 (24%)
		ERAP1_C	536..855	CDD:463368	79/340 (23%)