Protein Alignment CG4467 and Rnpep

DIOPT Version :10

• Sequence 1: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Sequence 2: NP_112359.2
• Gene: Rnpep / 81761
• RGDID: 621137
• Length: 650
• Species: Rattus norvegicus
• Alignment Length: 602
• Identity: 111/602 - (18%)
• Similarity: 192/602 - (31%)
• Gaps: 196/602 - (32%)

  Fly   176 FIVLHIQ-DLNVTEKAIVTPGPKGYALKIVKVLEFPPRQQLYIEVKERLKKKSNYTLNLRWYSKL 239
            |.:||:. ||. .|.....|||....|                        ....||.||...
  Rat    34 FEILHLHLDLR-AEFGPPGPGPGSRGL------------------------NGKATLELRCLL-- 71

  Fly   240 NPEPEGFYVDQYESSNGVERLLAATVFR--PNGARRAFPCFDEPHVRAPFRISVFRDRFHIGLSN 302
               |||....:.:|.:.:| ::|||:.|  |...::    ..||   .||....|.   |.|.:.
  Rat    72 ---PEGASELRLDSHSCLE-VMAATLLRGQPGDQQQ----LTEP---VPFHTQPFS---HYGQAL 122

  Fly   303 SIVHTTE---------DVGFYMGTGLLRDDFIETPPLPADAVAWVVSDFQRESLQPSAAYIPTTP 358
            .:|....         ::.:.:|.|              ..|.|:
  Rat   123 CVVFPKPCCAAERFRLELTYRVGEG--------------PGVCWL-------------------- 153

  Fly   359 APPGSGVGGKKSAQLNNYTQLKG----------KNPPVRNITALTHSLNVNLTPRQNLTVVQPTT 413
            ||  ....|||...:  |||.:.          ..|.|:    .|:|..|.:.  ...|.|...:
  Rat   154 AP--EQTAGKKKPFV--YTQGQAVLNRAFFPCFDTPAVK----CTYSALVEVP--DGFTAVMSAS 208

  Fly   414 TTAWPVNLNGNGK---------PSNLTSLSQSTGSSIKRAPSYTFYAPRDLLIRSSFILHTSRD- 468
            |  |  ...|..|         ||.|.:|:....:|.:       ..||..:.....::..:::
  Rat   209 T--W--ERRGPNKFFFQMNQPIPSYLIALAIGDLASAE-------VGPRSRVWAEPCLIEAAKEE 262

  Fly   469 ----VLEYLQTWLDISYPLT--KVDFVALPSLDRNMISSLGLVTLKTSFLTDPSSITSEQYQFSA 527
                :.|:|.|...:..|..  :.|.:.:|.    .....|:.....:|:| |..:..::
  Rat   263 YNGVIEEFLATGEKLFGPYVWGRYDLLFMPP----SFPFGGMENPCLTFVT-PCLLAGDR----- 317

  Fly   528 LRIAEAMVRQ----FFGGITSRKVLKDVWLWEGLIQYLGIHALAPLQETWPLREMYLLKMATAAL 588
             .:|:.::.:    :||.:.:.....:.||.||...|             ..|.:..:....|..
  Rat   318 -SLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMY-------------AQRRISTILFGAAYT 368

  Fly   589 DIDA------------IQGWDSIMN--------GTSHDGNNEEFFVQKTAAIFSMLHTAIG-EDR 632
            .::|            :.|.::.:|        |...|....|...:|.....|.|...:| :::
  Rat   369 CLEAATGRALLRQHMDVSGEENPLNKLRVKIEPGVDPDDTYNETPYEKGYCFVSYLAHLVGDQEQ 433

  Fly   633 FRGCLGSFLKVNRFRTAEPTDLWTICTK-----KANGSKNIKDM-MTLWTHQPGF-PLLTVTKMG 690
            |...|.:::...:|::....|......:     |..|..:|... ...|.:.||: |.|.....|
  Rat   434 FDKFLKAYVDEFKFQSILAEDFLEFYLEYFPELKKKGVDSIPGFEFNRWLNTPGWPPYLPDLSPG 498

  Fly   691 NSISISQRPFRPAEFLA 707
            :|:      .:|||.||
  Rat   499 DSL------MKPAEELA 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4467	NP_001036747.1	GluZincin	145..677	CDD:472708	100/569 (18%)
		ERAP1_C	783..1078	CDD:463368
Rnpep	NP_112359.2	M1_LTA4H	24..484	CDD:341062	100/569 (18%)
		Leuk-A4-hydro_C	530..645	CDD:462686