Protein Alignment CG4467 and RNPEPL1

DIOPT Version :10

• Sequence 1: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Sequence 2: NP_060696.4
• Gene: RNPEPL1 / 57140
• HGNCID: 10079
• Length: 725
• Species: Homo sapiens
• Alignment Length: 743
• Identity: 138/743 - (18%)
• Similarity: 227/743 - (30%)
• Gaps: 277/743 - (37%)

  Fly   188 EKAIVTPGPKGYALKIVKVLEFPP----------------RQQLYIEVKERLKKKSN-YTLNLRW 235
            |.|.|.|.|           |.||                ..||.:|::...::.:. ..|.|
Human    14 EAAPVRPPP-----------EPPPALDVASASSAQLFRLRHLQLGLELRPEARELAGCLVLEL-- 65

  Fly   236 YSKLNPEPEGFYVDQYESSNGVERLLAATVFRPNGARRAFPC---FDEP------------HVRA 285
             ..|.|.|....:|.:.:.    ||.:|...|...|....||   |..|            ...|
Human    66 -CALRPAPRALVLDAHPAL----RLHSAAFRRAPAAAAETPCAFAFSAPGPGPAPPPPLPAFPEA 125

  Fly   286 P----------FRISVFRDRFHIGLSNSIVHTTEDVGFYMGTGLLRDDFIETPPLPADAVAWVVS 340
            |          ||:..|.|   .|.|.::....|.........:||....:.|     |:.|:..
Human   126 PGSEPACCPLAFRVDPFTD---YGSSLTVTLPPELQAHQPFQVILRYTSTDAP-----AIWWLDP 182

  Fly   341 DFQRESLQP----------SAAYIP--TTPA---------PPGSGVGGKKSAQLNNYTQLKG--- 381
            :......:|          :.::.|  .|||         ...|||....||..:.|.:.:|
Human   183 ELTYGCAKPFVFTQGHSVCNRSFFPCFDTPAVKCTYSAVVKAPSGVQVLMSATRSAYMEEEGVFH 247

  Fly   382 ---KNPPVRNITALTHSLNVNLTPRQNLTVVQPTTTTAWPVNLNGNGKPSNLTSLSQSTGSSIKR 443
               ::|....:.||                            :.|:.||:::
Human   248 FHMEHPVPAYLVAL----------------------------VAGDLKPADI------------- 271

  Fly   444 APSYTFYAPRDLLIRSSFILHTSRDVLE-YLQTWLDIS------YPLTKVDFVALPSLDRNMISS 501
                   .||..:.....:|.|:...|. .::.||..:      |...:.|.|.||       .|
Human   272 -------GPRSRVWAEPCLLPTATSKLSGAVEQWLSAAERLYGPYMWGRYDIVFLP-------PS 322

  Fly   502 LGLVTLKTSFLTDPSSITSEQYQFSALRIAEAMVRQFFGGITSRKVLKDVWLWEGLIQYLGIH-- 564
            ..:|.::...||...|...|..:|..:.:...:...:||...:....:::||.|||..|....
Human   323 FPIVAMENPCLTFIISSILESDEFLVIDVIHEVAHSWFGNAVTNATWEEMWLSEGLATYAQRRIT 387

  Fly   565 ------ALAPLQETWPL----REMYLLKMATAALDIDAIQGWDSIMN----------GTSHDGNN 609
                  |...|:..:.|    |:|.||             |.||.::          ..||..|
Human   388 TETYGAAFTCLETAFRLDALHRQMKLL-------------GEDSPVSKLQVKLEPGVNPSHLMN- 438

  Fly   610 EEFFVQKTAAIFSMLHTAIGE-DRFRGCLGSFLKVNRFRTAEPTDL------------------- 654
             .|..:|.......|....|: .||...|.::::..:|.:....||
Human   439 -LFTYEKGYCFVYYLSQLCGDPQRFDDFLRAYVEKYKFTSVVAQDLLDSFLSFFPELKEQSVDCR 502

  Fly   655 -------WTICT-------KKANGS---KNIKDMMTLWTHQPGFPLLTVTKMGNSISISQ-RPFR 701
                   |...|       ..:.||   :.::.:..|||.:   ||.......::|.||: |.|:
Human   503 AGLEFERWLNATGPPLAEPDLSQGSSLTRPVEALFQLWTAE---PLDQAAASASAIDISKWRTFQ 564

  Fly   702 PAEFLAIHDDSYDGNNYNKTTLNATDMPSTVATTTQGSKHKVAPHMKWIFPVTYVTDINNVSETL 766
            .|.||   |...||          :.:|..|                       |..::....:|
Human   565 TALFL---DRLLDG----------SPLPQEV-----------------------VMSLSKCYSSL 593

  Fly   767 WMQNVDVTFNVPENVKWIKVNAIQNGYY 794
                :| :.|....::|::: .::|.||
Human   594 ----LD-SMNAEIRIRWLQI-VVRNDYY 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4467	NP_001036747.1	GluZincin	145..677	CDD:472708	114/623 (18%)
		ERAP1_C	783..1078	CDD:463368	4/12 (33%)
RNPEPL1	NP_060696.4	M1_LTA4H	29..512	CDD:341062	101/567 (18%)
		Leuk-A4-hydro_C	560..673	CDD:462686	18/98 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	676..699