Protein Alignment CG4467 and anpeplb

DIOPT Version :10

• Sequence 1: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Sequence 2: NP_001038326.1
• Gene: anpeplb / 558452
• ZFINID: ZDB-GENE-030131-4781
• Length: 946
• Species: Danio rerio
• Alignment Length: 1095
• Identity: 247/1095 - (22%)
• Similarity: 442/1095 - (40%)
• Gaps: 252/1095 - (23%)

  Fly   100 CSCGSKTVSG--YETDEENN--TQPFNPIATNGEPFPWLEKM-LPTSVRPLRYMVTIHPNLTTLD 159
            ||.|...|..  ::....||  |.|..||.....|....|.: ||.|:.|..|.|.:.|.|....
Zfish    21 CSVGCLVVMAVFFQIQVGNNKPTPPPRPILPTPLPTDLPESLRLPDSLIPESYNVFLQPYLYAAI 85

  Fly   160 VK----------GQVTIDLHVEKETNFIVLHIQDLNVT----------EKAIVTPGPKGYALKIV 204
            ..          |..|:.::..|.::.:.||:.::|||          ||..:    |||  :|.
Zfish    86 TNNYTEQSYLFTGNSTVRVNCTKTSSRVFLHVHNINVTAVEVRKSDTNEKLPL----KGY--QIF 144

  Fly   205 KVLEFPPRQQLYIEVKERLKKKSNYTLNLRWYSKLNPEPEGFYVDQYESSNGV-----ERLLAAT 264
            |    .....|.|.::..:|:...|.:...:..:|..:..|||..:| :..|.     ||.||.:
Zfish   145 K----NETNFLDIHLEVAIKENGTYDIFTEFEGELLEDLTGFYASRY-TGKGTDDEDEERFLATS 204

  Fly   265 VFRPNGARRAFPCFDEPHVRAPFRISVFRDRFHIGLSNSIVHTTEDVGFYMGTGLLRDDFIETPP 329
            :.:|..||..|||||||.::|.|.|::                                 |..|.
Zfish   205 LLQPTDARTVFPCFDEPAMKAVFTITI---------------------------------IHRPE 236

  Fly   330 LPADAVAWVVSDFQRESLQPSAAYIPTTPAPPGSGVGGKKSAQLNNYTQLKGKNPPVRNITALTH 394
            :.|.:                            :..|..::.|:|....::....|.:.::  ::
Zfish   237 IRARS----------------------------NEDGDPRTIQINGTDWIRTTFKPTKKMS--SY 271

  Fly   395 SLNVNLTPRQNLTVVQPTTTTAWPVNLNGNGKPSNLTSLSQSTGSSIKRAPSYTFYAPRDLLIRS 459
            .|...:......:.|...|.|  .::::|.         |::..:.                 .:
Zfish   272 LLGFIIYDTHTFSYVSKGTRT--KIHVHGR---------SEAIDAG-----------------HA 308

  Fly   460 SFILHTSRDVLEYLQTWLDISYPLTKVDFVALPSLDRNMISSLGLVTLKTSFL--TDPSSITSEQ 522
            .:.|.|:..:|.:.:....:.||::|:|.:|||......:.:.|.::.:.|.|  ...::.|.::
Zfish   309 DYALETTETILSHYENIFGLRYPMSKIDQIALPDFGVRAMENWGFISYQESGLLYDKETASTFDE 373

  Fly   523 YQFSALRIAEAMVRQFFGGITSRKVLKDVWLWEGLIQYL---GIHALAPLQETWPLREMYLLKMA 584
            .|.:.| ||..:..|:||.:.:.....|:||.||...|:   |:.|:.     |.|:::.:|:..
Zfish   374 EQVTTL-IAHELAHQWFGNLVTMSWWNDLWLKEGFATYMSYKGVEAVG-----WDLKDLIVLREI 432

  Fly   585 TAALDIDAIQGWDSIMNGTSHDGNNEEFFVQ---------------KTAAIFSMLHTAIGEDRFR 634
            ..|..:|::        .|||..:...:.||               |.||:..||.|.:||:.|.
Zfish   433 QTAFQMDSL--------NTSHPLSMNAYDVQTSSQISELFDDITYSKGAAVLRMLATRMGENEFM 489

  Fly   635 GCLGSFLKVNRFRTAEPTDLWTICTKKANGSKNIK--DMMTLWTHQPGFPLLT-VTKMGNSISIS 696
            ..:..:|...:|....|.|||. |   .|...:||  :.|..||.:.|:|:|| :|..|::   |
Zfish   490 KGVKMYLSKFQFENTVPKDLWE-C---LNMDTHIKVDEFMKTWTEEVGYPVLTIITDTGDT---S 547

  Fly   697 QRPFRPAEFLAIHDDSYDGNNYNKTTLNATDMPSTVATTTQGSKHKVAPHMKWIFPVTYVTDINN 761
            |.     :||...:..:|.                                .|..|:.|:|....
Zfish   548 QE-----QFLLKKEGGHDS--------------------------------LWHIPIKYMTLKAG 575

  Fly   762 VSETLWMQNVDVTFNVPENV--------KWIKVNAIQNGYYRVVYNDDNWASLIEELAANPNRFT 818
            |.|   ..|. .|...|:.:        .|:..|....|:|||.|:::||..|..:|..|.....
Zfish   576 VKE---FPNF-FTDKGPDPIPDFKIGKDNWLLANINCTGFYRVNYDEENWNRLTAQLQKNHRIIP 636

  Fly   819 SEDRLGMLSDAFTLCHANLLPCEITMNMIQYLPSETHYGPMALALRHLEKWRRILKYSECFLMLS 883
            ..:|..::.|||.|..|:.|...|.:|:.:||.::..|.|...||::|:.:..:...||.:..:.
Zfish   637 LINRGQLIDDAFNLARAHRLNVTIALNLTKYLINDLEYIPWESALKNLDFFTLMFDRSEVYGPIM 701

  Fly   884 EFIKMKISTVMEKV-GWSDDG--------DVATRLLRPEVLLASVLWEDIDSITKAKNMLNQYLY 939
            ::::..::.:.|:. .::.:|        |...::....|..::.|.|   .||.||::.:.  |
Zfish   702 KYLRNLVTPLYEEYEEYTINGTIPIEKYTDQCNQVNAITVACSNGLPE---CITMAKDLFSD--Y 761

  Fly   940 YNGT-AIPPNLREVVYTGSILSGEYIYWQHCWERFVNLQRTSETFVERMQLLRALGRTKDAWLQN 1003
            .||: .|.||||..||..::.||:...|::.||.:    :.:....|:.:|..||..||:.||.|
Zfish   762 KNGSNPIHPNLRRAVYCSAVASGDEDDWEYVWEEY----QKATVAAEKDKLRYALSCTKEIWLLN 822

  Fly  1004 RLLSHVTMLPTE----EVVQVLKAIAGTPTGGAMACRFLQAKWFELEKRLGPGTISFAKVISAIT 1064
            |.|.: |:.|::    ::|..:..||....|..:|..|::..|..:.:..|.|.||...::..:|
Zfish   823 RYLQY-TLEPSKIRKMDMVSTISYIAQNVAGQPLAWDFIRGHWSYITQEYGAGIISLGSLLDVVT 886

  Fly  1065 QYGATKFDYDELKSLVH---RFGRGHGMSVLNMTLSSVASNVEWVARSQTSLYKW 1116
            :..:|:.:.:|||.|..   :..:......|...:...|:|:.||..::..:..|
Zfish   887 KRFSTEVELEELKQLQREQIQDDKWIAARALEQVIERTAANIIWVKENKQVVKDW 941

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4467	NP_001036747.1	GluZincin	145..677	CDD:472708	119/578 (21%)
		ERAP1_C	783..1078	CDD:463368	83/308 (27%)
anpeplb	NP_001038326.1	M1_APN-Q_like	71..530	CDD:341064	119/578 (21%)
		ERAP1_C	601..926	CDD:463368	86/334 (26%)