Protein Alignment CG4467 and CG46339

DIOPT Version :10

• Sequence 1: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Sequence 2: NP_001263001.1
• Gene: CG46339 / 44359
• FlyBaseID: FBgn0285963
• Length: 1194
• Species: Drosophila melanogaster
• Alignment Length: 1087
• Identity: 246/1087 - (22%)
• Similarity: 424/1087 - (39%)
• Gaps: 260/1087 - (23%)

  Fly   114 EENNTQPFNPIATNGEPFPWLEKMLPTSVRPLRYMVTIHPNLTTLDVKGQVTIDLH--VEKETNF 176
            |:|.|:|.|      .|....|     ..|||.|.:.|.|::.|....|.:||::.  |.|.|::
  Fly   277 EDNTTKPIN------RPLKLYE-----GWRPLHYSLLIEPSVATSISNGSLTIEIERDVSKVTSW 330

  Fly   177 --IVLHIQDLNVTEKAIVTPGPKG----------------------YALKIVKVLEFPPRQQLYI 217
              |||.:.:::::...::.....|                      :.:.:.|.|.        :
  Fly   331 EPIVLDVHNVSISNVRVIRALADGASNASEEQDLDFDSDYGEDNATFVINLSKTLA--------V 387

  Fly   218 EVKERLKKKSNYTLNLRWYSKLNPEPEGFYVDQY---ESSNGVERLLAATVFRPNGARRAFPCFD 279
            |.:.|:      .|:|.:.|::....:|.|...|   ::.|  |..:.:|.|.|..|||||||||
  Fly   388 ETQLRV------LLSLDFVSQVTDTLQGIYKTSYTNPDTKN--EEWMISTQFSPVDARRAFPCFD 444

  Fly   280 EPHVRAPFRISVFRD-RFHIGLSNSIVHTTEDVGFYMGTGLLRDDFIETPPLPADAVAWVVSDFQ 343
            .|.::|.|.||:.|. :|.:.|||    ..:........|.:||||..||.:|...||::||:.
  Fly   445 RPDMKANFSISIVRPMQFKMALSN----MPKSGSRRFRRGFIRDDFETTPKMPTYLVAFIVSNM- 504

  Fly   344 RESLQPSAAYIPTTPAPPGSGVGGKKSAQLNNYTQLKGKNPPVRNITALTHSLNVNLTPRQNLTV 408
                      :.:..|...||                                   ||||..:
  Fly   505 ----------VDSRLASQDSG-----------------------------------LTPRVEI-- 522

  Fly   409 VQPTTTTAWPVNLNGNGKPSNLTSLSQSTGSSIKRAPSYTFYAPRDLLIRSSFILHTSRDVLEYL 473
                    |.       :|       |..|        .|.||.:.:           |..|.|.
  Fly   523 --------WT-------RP-------QFVG--------MTHYAYKMV-----------RKFLPYY 546

  Fly   474 QTWLDISYPLTKVDFVALPSLDRNMISSLGLVTLKTSFLTDPSSI----TSEQYQFSALRIAEAM 534
            :.:..|...|.|:|.|::|......:.:.||:|.:.|.|..|..:    :||..|..|..||..:
  Fly   547 EDFFGIKNKLPKIDLVSVPDFGFAAMENWGLITFRDSALLVPEDLQLASSSEHMQVVAGIIAHEL 611

  Fly   535 VRQFFGGITSRKVLKDVWLWEGLIQYLGIHALAPLQETWPLREMYLLKMATAALDIDAIQGWDSI 599
            ..|:||.:.:.|...|:||.||...|:...||......:...:...:.....:::.||    |:.
  Fly   612 AHQWFGNLVTPKWWDDLWLKEGFACYMSYKALEHAHPEFQSMDTLTMLEFKESMEHDA----DNT 672

  Fly   600 MNGTSHDGNN--------EEFFVQKTAAIFSMLHTAIGEDRFRGCLGSFLKVNRFRTAEPTDLWT 656
            .:..|.|..:        :.....|...:..||::.:|:..||......||...:...:..|||.
  Fly   673 SHAISFDVRSTNDVRRIFDPISYSKGTILLRMLNSIVGDVAFRSATRDLLKKFAYGNMDRDDLWA 737

  Fly   657 ICTKKAN------GSKNIKDMMTLWTHQPGFPLLTVTKMGNSISISQRPFRPAEFLAIHDDSYDG 715
            :.|:..:      ...::|.:|..|..|||:|::.|.:.|..:.:.|..:.
  Fly   738 MLTRHGHEQGTLPKDLSVKQIMDSWITQPGYPVVNVERRGADLVLRQERYL-------------- 788

  Fly   716 NNYNKTTLNATDMPSTVATTTQGSKHKVAPHMKWIFPVTYVTDI----NNVSETLWMQNVD---- 772
                        :||          ...|....|..|:|:.||.    :|: .|.||::.|
  Fly   789 ------------LPS----------KNTADQSTWFIPITFETDELRKGDNI-PTHWMRSEDEEEL 830

  Fly   773 VTFNV------PENVKWIKVNAIQNGYYRVVYNDDNWASLIEELAANPNRFTSEDRLGMLSDAFT 831
            :..||      .:||.::.:|  :.|||||.|:..:|.:|.:..:..| |.|   |..:|.||..
  Fly   831 IVGNVFAHSSNSDNVIYLNLN--RQGYYRVNYDMTSWLALKKNFSTLP-RIT---RAQLLDDALH 889

  Fly   832 LCHANLL----PCEITMNMIQYLPSETHYGPMALALRHLEKWRRI--LKYSECFLMLSEFIKMKI 890
            |..|..|    |....|.:...:..|..:......|.:|     |  ||....:.....|:|..:
  Fly   890 LSQAEYLTYDIPLTFLMELFDAVDDELLWIAAKPGLNYL-----IYNLKREPAYETFRAFMKFIV 949

  Fly   891 STVMEKVGWSDDGDVATRLLRPEVLLASVLWE-DIDSIT-KAKNMLNQYLY-YNGTAIPPNLREV 952
            ....:..|..:..:.:...|:...|:|....: :.|..| ||:....:::. .....|.|||:.|
  Fly   950 RPAFDHYGLHEPDNESHLQLKHRALVAYFACKFNYDRCTQKAQMKFREWMRDPKNNPIKPNLKSV 1014

  Fly   953 VYTGSILSGEYIYWQHCWERFVNLQRTSETFVERMQLLRALGRTKDAWLQNRLLSHVTMLPTEEV 1017
            :|..|:..|....|...::::    :|:.:..|:.::|.:||.|...||.::.| ::|:.||..:
  Fly  1015 IYCTSLAEGSSPEWYFAYKQY----KTTTSASEKEEILTSLGCTTKPWLLSKYL-NMTINPTSGI 1074

  Fly  1018 VQ-----VLKAIAGTPTGGAMACRFLQAKWFELEKRLGPGTISFAKVISAITQYGATKFDYD--- 1074
            ::     ..:|:|....|..:|..|||....|:.:..|.|..:.:::|.::|.|  ...||.
  Fly  1075 LKQDGALAFRAVASNAIGHEIAFDFLQGNIKEIVEYYGDGFSTLSEMIKSLTIY--MNKDYHKHQ 1137

  Fly  1075 --ELKSLVHRFGRGHGMSVLNMTLSSVASNVEWVARSQTSLYKWVEG 1119
              :|.:...:.|.....|.:.:.|..|.:|:.|.:.|..||..::||
  Fly  1138 LLDLAATCRKLGLHAVESAIELALEQVNNNIYWRSHSYHSLKNFLEG 1184

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4467	NP_001036747.1	GluZincin	145..677	CDD:472708	128/579 (22%)
		ERAP1_C	783..1078	CDD:463368	74/313 (24%)
CG46339	NP_001263001.1	M1_APN-Q_like	297..764	CDD:341064	128/579 (22%)
		ERAP1_C	846..1126	CDD:463368	69/295 (23%)