Protein Alignment CG4467 and CG32473

DIOPT Version :10

• Sequence 1: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Sequence 2: NP_731787.1
• Gene: CG32473 / 41636
• FlyBaseID: FBgn0052473
• Length: 1025
• Species: Drosophila melanogaster
• Alignment Length: 1095
• Identity: 259/1095 - (23%)
• Similarity: 459/1095 - (41%)
• Gaps: 180/1095 - (16%)

  Fly    74 LLVAGIVLGSLLLTAIIIAYAGPQNDCSCGSK-----TVSGYETDEEN--NTQPFNPIATNGEPF 131
            |::.|.:||:|:.....||....:...:..|:     |:.....|.:.  :|:|...:.::...:
  Fly    46 LVLCGFLLGALVYVGKNIAEEHQRQQHANASQWALNSTIRTVYVDRDQLLSTKPIISVLSDNRFY 110

  Fly   132 ----PWLEK-----------------------MLPTSVRPLRYMVTIHPNLTTLDVKGQVTIDLH 169
                |..:|                       .||..::|.:|.:.:.|:|...:..|.::|.|.
  Fly   111 TTQVPTSKKSSIMATVAPAVKAASKVLQNLGFRLPKQIKPSKYRLHLRPDLERKNYSGNISISLQ 175

  Fly   170 VEKETNFIVLHIQDLNVTEKAIVTPGPKGYALK-IVKVLEFP-PRQQLYIEVKERLKKKSNYTLN 232
            |.:...||.:|::.|||:...:......|..|| |...|.|. |..:.::...|:..:..||:|.
  Fly   176 VLEPIAFIPVHVKQLNVSTVEVKRLDESGAPLKDITPTLTFAHPEFEYWVTEFEQPLEAGNYSLL 240

  Fly   233 LRWYSKLNPEPEGFYVDQY-ESSNGVERLLAATVFRPNGARRAFPCFDEPHVRAPFRISVFR--- 293
            |.:...|.....|.|...| :......|.:.:|.|.|..||:||||||||.::|.|.|:|.|
  Fly   241 LNFTGSLVDRITGMYQSSYLDKLKNRSRSIISTKFEPTYARQAFPCFDEPALKAQFTITVARPSG 305

  Fly   294 DRFHIGLSNSIVHTTEDVGFYMGTGLLRDDFIETPPLPADAVAWVVSDFQRESLQPSAAYIPTTP 358
            |.:|: |||..|.:.     |:...:....|.||.|:.....|:||||||         |..||
  Fly   306 DEYHV-LSNMPVASE-----YVDGDITEVTFAETVPMSTYLAAFVVSDFQ---------YKETT- 354

  Fly   359 APPGSGVGGKKSAQLNNYTQLKGKNPPVRNITALTHSLNVNLTPRQNLTVVQPTTTTAWPVNLNG 423
                                                                             
  Fly   355 ----------------------------------------------------------------- 354

  Fly   424 NGKPSNLTSLSQSTGSSIKRAPSYTFYAPRDLLIRSSFILHTSRDVLEYLQTWLDISYPLTKVDF 488
                        ..|:||    :...|||...:.::.:.|.|:..|:.|...:.::||.|.|:|.
  Fly   355 ------------VEGTSI----ALKVYAPPAQVEKTQYALDTAAGVMAYYINYFNVSYALPKLDL 403

  Fly   489 VALPSLDRNMISSLGLVTLK-TSFLTDPSSITSEQYQFSALRIAEAMVRQFFGGITSRKVLKDVW 552
            ||:|......:.:.||||.: |:.|.|.|:.:|...|..|:.:|..:..|:||.:.:.....|:|
  Fly   404 VAIPDFVSGAMENWGLVTFRETALLYDESTSSSVNKQRVAIVVAHELAHQWFGNLVTMNWWNDLW 468

  Fly   553 LWEGLIQYLGIHALAPLQETWPLREMYLLKMATAALDIDAIQGWDSIMNGTSHDGNNEEFF---- 613
            |.||...:|....:..:...|.:...::::.....|.|||......|:..........|:|
  Fly   469 LNEGFASFLEYKGVKQMHPEWDMDNQFVIEELHPVLTIDATLASHPIVKSIESPAEITEYFDTIT 533

  Fly   614 VQKTAAIFSMLHTAIGEDRFRGCLGSFLKVNRFRTAEPTDLWTICTKKANGSKNIKDMMTLWTHQ 678
            ..|.||:..||...:||::.|.....:|..:.:.||...|..|...::.....::|.:|..||.|
  Fly   534 YSKGAALVRMLENLVGEEKLRNATTRYLVRHIYSTATTEDYLTAVEEEEGLEFDVKQIMQTWTEQ 598

  Fly   679 PGFPLLTVTKMGNSISISQRPFRPAEFLAIHDDSYDGNNYNKTTLNATDMPSTVATTTQGSKHKV 743
            .|.|::.|.|.|::..::|:     .|||..||                    .|...:.|..
  Fly   599 MGLPVVEVEKSGSTYKLTQK-----RFLANEDD--------------------YAAEAEASSF-- 636

  Fly   744 APHMKWIFPVTYVTDINNVSETLWMQNVD--VTFNVPENVKWIKVNAIQNGYYRVVYNDDNWASL 806
              :.:|..|:||.:.||:..::|...:.|  .|..:||...|||:|..|.|||||.|..:.||.|
  Fly   637 --NYRWSIPITYTSSINSEVQSLIFNHNDNEATITLPEEASWIKINTNQVGYYRVNYGSEQWAEL 699

  Fly   807 IEELAANPNRFTSEDRLGMLSDAFTLCHANLLPCEITMNMIQYLPSETHYGPMALALRHLEKWRR 871
            |..|..:...|::.||..:|:||.||..|..|...:.:::|.||.||..|.|.::....|...|.
  Fly   700 ISALKNSRETFSTADRAHLLNDANTLAAAGQLNYSVALDLISYLESEQDYVPWSVGTSALATLRN 764

  Fly   872 ILKYSECFLMLSEFIKMKISTVMEKVGWSDDGDVATRLLRPEVLLASVLWEDIDSITKAKNMLNQ 936
            .:.|::.:...:.:.:..::.::|||.::...|.....||.:||.::.......|:.:|..:.||
  Fly   765 RVYYTDLYTNYTTYARKLLTPIVEKVTFTVAADHLENRLRIKVLSSACSLGHESSLQQAVTLFNQ 829

  Fly   937 YLYYNGTAIPPNLREVVYTGSILSGEYIYWQHCWERFVNLQRTSETFVERMQLLRALGRTKDAWL 1001
            :|....|...|::|:|||...:   :.:..:..|::...|........|:::|:..|...:..||
  Fly   830 WLASPETRPNPDIRDVVYYYGL---QQVNTEAAWDQVWKLYLDESDAQEKLKLMNCLTAVQVPWL 891

  Fly  1002 QNRLLSHV---TMLPTEEVVQVLKAIAGTPTGGAMACRFLQAKWFELEKRLGPGTISFAKVISAI 1063
            ..|.::..   :.:..::...:|..|:..|.|.::...:::..|.:|..|.|....:..::|..|
  Fly   892 LQRYINWAWDESNVRRQDYFTLLGYISTNPVGQSLVWDYVRENWEKLVDRFGINERTLGRLIPTI 956

  Fly  1064 TQYGATKFDYDELKSLVHRFGR-GHGMSVLNMTLSSVASNVEWVARSQTSLYKWV 1117
            |...:|:...:|::....::.. |.|.:.....|.:|.:|::|:|.::..:.:|:
  Fly   957 TARFSTETKLEEMQQFFAKYPEAGAGTAARQQALEAVKANIKWLAANKAQVGEWL 1011

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4467	NP_001036747.1	GluZincin	145..677	CDD:472708	132/542 (24%)
		ERAP1_C	783..1078	CDD:463368	76/297 (26%)
CG32473	NP_731787.1	M1_APN-Q_like	151..597	CDD:341064	132/542 (24%)
		ERAP1_C	676..995	CDD:463368	80/321 (25%)