Protein Alignment CG4467 and CG8774

DIOPT Version :10

• Sequence 1: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Sequence 2: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Alignment Length: 1010
• Identity: 258/1010 - (25%)
• Similarity: 434/1010 - (42%)
• Gaps: 174/1010 - (17%)

  Fly   138 LPTSVRPLRYMVTIHPNLTTLDVKGQVTIDLHVEKETNFIVLHIQDLNVTEKAIVTPGPKGYALK 202
            |||::.|..|.:..||:|.|.:..||..|.:.|.:.||.|:||...|::|...::....:.:.|:
  Fly    68 LPTNLVPTHYELYWHPDLETGNFTGQQRISIKVVEATNQIILHSYLLDITSVYVLNREVEKFELE 132

  Fly   203 IVKVLEFPPRQQLYIEVKERLKKKSNYTLNLRWYSKLNPEPEGFYVDQYESSNGVERLLAATVFR 267
                   ..||.|.|.:.|.|...::.||.:.:..::..:..|.|...|.:..|..|.::.|.|.
  Fly   133 -------EERQFLIITLTEELAVDASITLGIIFGGQMKDKLVGLYSSTYLNEAGATRTISTTKFE 190

  Fly   268 PNGARRAFPCFDEPHVRAPFRISVFRDRFHIGLSNSIVHTTEDVGFYMGTGLLRDDFIETPPLPA 332
            |..||:||||||||.::|.|.|:|             ||
  Fly   191 PTYARQAFPCFDEPAMKATFAITV-------------VH-------------------------- 216

  Fly   333 DAVAWVVSDFQRESLQPSAAYIPTTPAPPGSGVGGKKSAQLNNYTQLKGKNPPVRNITALTHSLN 397
                            ||.:|...      |.:...:|..|.:||:             .....:
  Fly   217 ----------------PSGSYHAV------SNMQQTESNYLGDYTE-------------AIFETS 246

  Fly   398 VNLTPRQNLTVVQPTTTTAWPVNLNGNGKPSNLTSLSQSTGSSIKRAPSYTFYAPRDLLIRSSFI 462
            |:::......:|....:.:..|..||.|:..::.:                 ||....:.:..|.
  Fly   247 VSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQA-----------------YATSHQINKVEFA 294

  Fly   463 LHTSRDVLEYLQTWLDISYPLTKVDFVALPSLDRNMISSLGLVTLK-TSFLTDPSSITSEQYQFS 526
            |...:.|.||...:..:.|||||:|..|:|......:...||||.: |:.|.|||..::...|..
  Fly   295 LEFGQAVTEYYIQYYKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSI 359

  Fly   527 ALRIAEAMVRQFFGGITSRKVLKDVWLWEGL---IQYLGIHALAPLQETWPLREMYLLKMATAAL 588
            |..:|..:..|:||.:.:.|...|:||.||.   :||.|::|:.|   .|.:.|.:.:......|
  Fly   360 AGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHP---DWGMLEQFQIVALQPVL 421

  Fly   589 DIDAIQGWDSIMNGTSHDGNNEEFF----VQKTAAIFSMLHTAIGEDRFRGCLGSFLKVNRFRTA 649
            ..||......|:............|    .:|..::..||.|.:|.::|...:.::|..::|...
  Fly   422 LYDAKLSSHPIVQKVESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQFNNT 486

  Fly   650 EPTDLWT----ICTKKANGSKNIKDMMTLWTHQPGFPLLTVTKMGN-SISISQRPF--RPAEFLA 707
            ...|..|    :.|     ..:||.:|..||.|.|:|:|.|:|:.: |..::|:.|  .||.:..
  Fly   487 VTDDFLTEVEAVVT-----DLDIKKLMLTWTEQMGYPVLNVSKVADGSFKVTQQRFLSNPASYEE 546

  Fly   708 IHDDSYDGNNYNKTTLNATDMPSTVATTTQGSKHKVAPHMKWIFPVTYVTDINNVSETLWMQNVD 772
            ...||..|                               .||..|:|:..|..:.:..::..:||
  Fly   547 APSDSAYG-------------------------------YKWSVPITWFADDGSENSFIYDYDVD 580

  Fly   773 -VTFNVPENVKWIKVNAIQNGYYRVVYNDDNWASLIEELAANPNRFTSEDRLGMLSDAFTLCHAN 836
             |...||..|:|||:|..|.|||||.|.:..||.||::|..:|.||...||..:|:|||.|..||
  Fly   581 SVGIAVPSEVQWIKLNVNQTGYYRVNYEESLWALLIQQLTTSPARFEIADRGHLLNDAFALADAN 645

  Fly   837 LLPCEITMNMIQYLPSETHYGPMALALRHLEKWRRILKYSECFLMLSEFIKMKISTVMEKVGWSD 901
            .|..:|.::|..||..|..:.|..:|...|....|.|.:||.::....:.:..|:.|.|:|||:.
  Fly   646 QLSYKIPLDMTAYLAQERDFVPWYVASNKLRSLHRSLMFSEGYVSYLTYARSLIAGVYEEVGWTV 710

  Fly   902 DGD--VATRLLRPEVLLASVLWEDIDSITKAKNMLNQYLYYNGTAIPPNLREVV-YTGSILSGEY 963
            |.|  :..| ||..:|.|:......|.:.:|....:.:|....|...|:|||:| |.|...|...
  Fly   711 DADNHLKNR-LRVSILTAACALGVPDCLQQASERFSTFLENPTTRPSPDLREIVYYYGMQQSTSQ 774

  Fly   964 IYWQHCWERFVNLQRTSETFV-ERMQLLRALGRTKDA-WLQNRLL---SHVTMLPTEEVVQVLKA 1023
            ..|...::.||     :||.. |:::|:..|...::: :|.:.|.   |..:::.:::....::.
  Fly   775 SSWDQLFQLFV-----AETDASEKLKLMYGLSGVRNSQYLFDFLAQASSDESIVRSQDYFTCVQY 834

  Fly  1024 IAGTPTGGAMACRFLQAKWFELEKRLGPGTISFAKVISAITQYGATKFDYDELKSLVHRFGR--- 1085
            ||..|.|..:...|.:.:|.:|..|.|....:|.::|:.||...|:....:|::   |.|.:
  Fly   835 IAANPVGEPVVWEFYREQWPQLTTRFGLNNRNFGRLIAQITANFASSVKLEEVQ---HFFSKYPE 896

  Fly  1086 -GHGMSVLNMTLSSVASNVEWVARSQTSLYKWVEG 1119
             |.|.:.....:.::..|:||::|::..:..|:.|
  Fly   897 SGAGANSRLEAVETIKYNIEWLSRNEADITDWLSG 931

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4467	NP_001036747.1	GluZincin	145..677	CDD:472708	126/543 (23%)
		ERAP1_C	783..1078	CDD:463368	92/302 (30%)
CG8774	NP_650274.2	M1_APN-Q_like	75..513	CDD:341064	126/543 (23%)
		ERAP1_C	592..912	CDD:463368	96/328 (29%)