Protein Alignment CG4467 and CG6071

DIOPT Version :10

• Sequence 1: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Sequence 2: NP_648488.1
• Gene: CG6071 / 39308
• FlyBaseID: FBgn0036186
• Length: 962
• Species: Drosophila melanogaster
• Alignment Length: 1091
• Identity: 223/1091 - (20%)
• Similarity: 396/1091 - (36%)
• Gaps: 281/1091 - (25%)

  Fly   136 KMLPTSVRPLRYMVTIHPNLTTLDVKGQ----VTIDLHVEKETNFIVLHIQDLNVTEKAIVT--- 193
            |:..:.|:||||.:||...|.:.|.:.|    |:||:...:.|.  |:::..||:|.....|
  Fly    16 KLAESFVKPLRYNLTILTRLGSEDEQNQFEGIVSIDIEATQPTR--VIYLNSLNITISRQRTWIY 78

  Fly   194 ---PGPKGYALKIVKVLEFPPRQQLYIEVKERLKKKSNYTLNLRWYSKLNPEPE-GFYVDQYESS 254
               .|.|..||:|.::::.....::.||:.  |:....||||:.:...|:...: |::...|:.:
  Fly    79 RWASGRKIGALQIKRIIKKTSLIKIVIELP--LRSGEIYTLNMLFSGNLDRSQQYGYFAGYYDKT 141

  Fly   255 NGVERLLAATVFRPNGARRAFPCFDEPHVRAPFRISVFRDRFHIGLSNSIVHTTEDVGFYMGTGL 319
            ..|  ..:||...|:.|...|||||:|..|.|:.|::..||.::.|||  :...|:..:......
  Fly   142 PRV--FYSATRLEPDYAHTVFPCFDDPRFRTPYNITLVHDRKYVALSN--MPPVEEKPYKEIENY 202

  Fly   320 LRDDFIETPPLPADAVAWVVSDFQRESLQPSAAYIPTTPAPPGSGVGGKKSAQLNNYTQLKGKN- 383
            :...|:.:|||....|.|.:...::....|:||                            |:|
  Fly   203 VSTTFMGSPPLATQQVMWTLHQLEKVYSGPAAA----------------------------GENI 239

  Fly   384 -----PPVRNITALTHSLNVNLTPRQNLTVVQPTTTTAWPVNLNGNGKPSNLTSLSQSTGSSIKR 443
                 |.:....|....:..||..:.......|.     |...:..||..::.
  Fly   240 TVWSRPHLAEKLAKVPEMTPNLFSKYETLFAYPL-----PKGADWGGKVDHVV------------ 287

  Fly   444 APSYT-FYAPRDLLIRSSFILHTSRDVLEYLQTWLDISYPLTKVDFVALPSLDRNMISSLGLVTL 507
            .|.|| .|:.:.:::....|:.:.::.||.||..|
  Fly   288 LPRYTEMYSGQGIMVYGEDIVDSGQNGLESLQETL------------------------------ 322

  Fly   508 KTSFLTDPSSITSEQYQFSALRIAEAMVRQFFGGITSRKVLKDVWLWEGLIQYLGIHALAPLQET 572
                                   ||.:.||:.|.:.:.:...:.::..|:..||.:..:|..:|.
  Fly   323 -----------------------AELVARQWNGLLVNLEDSDEEYVRNGINYYLSVQVMAMDKEA 364

  Fly   573 WPLREMYLLKMATAALDIDAIQGWDSIMNGTSHDGNNEEFFVQKTAAIFSMLHTAIGEDRFRGCL 637
            :  ...:|.|.....|..|::....||.......| :::...:|...:..||..|:|:..|...|
  Fly   365 Y--NTTHLSKTRLDVLYHDSLAKVKSIATDVKESG-HQKLRKKKMCLLIHMLKVALGDKLFLKGL 426

  Fly   638 GSFLKVNRFRTAEPTDLWTICTKKANGSK------NIKDMMTLWTHQPGFPLLTVTKMGNSISIS 696
            ..|.|.....:|...:||....:.|..|.      ::..:|..|..|||||||||.:
  Fly   427 QEFFKRYANSSASSKELWEEFQRGARRSHQLPTGVSLPTVMESWMKQPGFPLLTVQR-------- 483

  Fly   697 QRPFRPAEFLAIHDDSYDGNNYNKTTLNATDMPSTVATTTQGSKHKV----APHMKWIFPVTYVT 757
                         ||:                 ..:.|.||...::.    :.:..|..||.|:.
  Fly   484 -------------DDA-----------------KQIVTITQSRYYQKYLDNSSNDCWWVPVAYIV 518

  Fly   758 DINNVSETLWM------QNVDVTFNVPENVKWIKVNAIQNGYYRVVYNDDNWASLIEELAANPNR 816
            ....:.:..|:      :::....::.....|:.:|.......||.|:..|...:.|.|..:..:
  Fly   519 RNLTLPQVEWLGCQKNSRDILELSHIANPEDWLLINVDAAVPLRVFYDSYNLQLISEALRQDFTQ 583

  Fly   817 FTSEDRLGMLSDAFTLCHANLLPCEITMNMIQYLPSETHYGPMALALRHLEKWRRILKYSECF-- 879
            .....|:.::.||.:|..:..||..:|:|:|.||.:||.......||.:|||.:.|::.:..|
  Fly   584 IPELSRIQLVDDALSLSWSGRLPYNVTLNVISYLSNETSVLVWETALLNLEKLQSIMRMTTGFRI 648

  Fly   880 --LMLSEFIKMKISTVM-----------------------EKVGWSDDGDV-------------- 905
              |.:.:.|:....|.:                       |..|.::..|.
  Fly   649 FKLYMQKLIEPAFKTTLNSLSTKARTGSEIPINTKSPVTTESSGTTESPDTTESPDTAESPDTTE 713

  Fly   906 -ATRLLRPEVLLASVLWEDIDSITKAKNMLNQYLY-------------------------YNGTA 944
             :.....|:...:|...|..|: ||:...|:..||                         .:.::
  Fly   714 SSNTTESPDTTESSDTTESPDT-TKSDLSLSAILYRLACQFEIKECLTDAQQRFQAAMDQKSSSS 777

  Fly   945 IPPNLREVVYTGSILSGEYIYWQHCWERFVNLQRTSETFVERMQLLRALGRTKDAWLQNRLLSHV 1009
            ||..:||:|....|.:|..::|....:.|..    ||...||..||.:|..|.:.|...:|||..
  Fly   778 IPEEIREIVLCRGIRNGLEVHWIMVRDMFFE----SENDKERSILLNSLSCTTEYWAMQKLLSWA 838

  Fly  1010 ---TMLPTEEVVQVLKAIAGTPTGGAMACRF--------LQAKWFELEKRLGPGTISFAKVISAI 1063
               ..:|......:|.|:..:|.|..:..:|        |::|..:|             :::..
  Fly   839 LDSKKVPRTMTASLLSAVLRSPLGYYVGKQFLIDHSKEILRSKDVKL-------------ILTPF 890

  Fly  1064 TQYGATKFDYDELKSLVHRFGRGHGMSVLNMTLSSVASNVEWVARSQTSLY 1114
            ....:||.::..|...:||......:|.|:.||.|....|.|    :.:||
  Fly   891 INAMSTKAEFSALNDHLHRNLPSSMVSGLSSTLESGLDRVNW----RNNLY 937

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4467	NP_001036747.1	GluZincin	145..677	CDD:472708	114/555 (21%)
		ERAP1_C	783..1078	CDD:463368	76/372 (20%)
CG6071	NP_648488.1	GluZincin	25..472	CDD:472708	114/555 (21%)
		ERAP1_C	550..930	CDD:463368	83/397 (21%)
		SSP160	691..>749	CDD:115579	11/58 (19%)