Protein Alignment CG4467 and Psa

DIOPT Version :10

• Sequence 1: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Sequence 2: NP_728614.1
• Gene: Psa / 38175
• FlyBaseID: FBgn0261243
• Length: 1075
• Species: Drosophila melanogaster
• Alignment Length: 1081
• Identity: 250/1081 - (23%)
• Similarity: 437/1081 - (40%)
• Gaps: 206/1081 - (19%)

  Fly    67 VCSQRRALLV---AGIVLGSLLLTAIIIAYAGPQNDCSCGSKTVSGYET---DEENNTQPFNPIA 125
            :|||.||:|.   |.::.|.            .::...|..:.:....|   .:|...:....:|
  Fly   159 LCSQYRAILAHTSADVIPGQ------------DRHHPGCNYQQIRRAHTQLLSKEQQLEQERKMA 211

  Fly   126 TNGEPFPWLEKMLPTSVRPLRYMVTIHPNLTTLDVKGQVTIDLHVEKETNFIVLHIQDLNVTEKA 190
            ...:    .|: |||:|.|..|.:.:.|||......|:..:.::|::.|..|.|:..|:.:....
  Fly   212 QKAK----FER-LPTNVVPRHYELLLQPNLKEFTFTGKTVVQVNVKEPTTQITLNALDIVLDSVE 271

  Fly   191 IVTPGPKGYALKIVKVLEFPPRQQLYIEVKERLKKKSNYTLNLRWYSKLNPEPEGFYVDQYESSN 255
            :.....|   ||..|::.....:...:|..:.:..::...|::.:..:||.:.:|||..:|...|
  Fly   272 LHFECSK---LKPEKIVYSAENETATLEFAQEIPAETQGVLHMSFTGELNDKMKGFYRSKYFGPN 333

  Fly   256 GVERLLAATVFRPNGARRAFPCFDEPHVRAPFRISVFRDRFHIGLSNSIVHTTEDVGFYMGTGLL 320
            |.||....|.|....|||.|||:|||.::|.|.|::...:..:.|||..| ..||   .:..||.
  Fly   334 GEERFAGVTQFEATDARRCFPCWDEPAIKATFDITLVVPKDRVALSNMPV-IKED---SLPDGLR 394

  Fly   321 RDDFIETPPLPADAVAWVVSDFQRESLQPSAAYIPTTPAPPGSGVGGKKSAQLNNYTQLKGKNPP 385
            |..|..||.:....||.||.:                                  |..::||:..
  Fly   395 RVRFDRTPIMSTYLVAVVVGE----------------------------------YDYVEGKSDD 425

  Fly   386 ---VRNITALTHSLNVNLTPRQNLTVVQPTTTTAWPVNLNGNGKPSNLTSLSQSTGSSIKRAPSY 447
               ||..|                           ||.....|
  Fly   426 GVLVRVFT---------------------------PVGKREQG---------------------- 441

  Fly   448 TFYAPRDLLIRSSFILHTSRDVLEYLQTWLDISYPLTKVDFVALPSLDRNMISSLGLVTLKTSF- 511
                        :|.|..:..||.|.:.:.:|:|||.|:|.:|:.......:.:.||||.:.:|
  Fly   442 ------------TFALEVATKVLPYYKDYFNIAYPLPKMDLIAISDFSAGAMENWGLVTYRETFV 494

  Fly   512 LTDPSSITSEQYQFSALRIAEAMVRQFFGGITSRKVLKDVWLWEG---LIQYLGIHALAPLQETW 573
            |.||.:.:..:.|..||.:...:..|:||.:.:.:....:||.||   .:::|.:|.|.|..:.|
  Fly   495 LVDPKNTSLMRKQSIALTVGHEIAHQWFGNLVTMEWWTHLWLNEGYASFVEFLCVHHLFPEYDIW 559

  Fly   574 PLREMYLLKMATAALDIDAIQGWDSIMNGTSHDGNNEEFF----VQKTAAIFSMLHTAIGEDRFR 634
               ..::..|.|.||::|:::....|.....|....:|.|    ..|.|::..|||..||||.||
  Fly   560 ---TQFVTDMYTRALELDSLKNSHPIEVPVGHPSEIDEIFDEISYNKGASVIRMLHDYIGEDTFR 621

  Fly   635 GCLGSFLKVNRFRTAEPTDLWTICTKKANGSKNIKDMMTLWTHQPGFPLLTVTKMGNSISISQRP 699
            ..:..:|..:::......|||....:.:  |||:.|:||.||...|||:::|.  ....|.:||.
  Fly   622 KGMNLYLTRHQYGNTCTEDLWAALQEAS--SKNVSDVMTSWTQHKGFPVVSVE--SEQTSKNQRL 682

  Fly   700 FR--PAEFLAIHDDSYDGNNYNKTTLNATDMPSTVATTTQGSKHKVAPHMKWIFPVTYVTDIN-- 760
            .|  ..:|.|      ||:..::..|                         |:.|::..|..|
  Fly   683 LRLKQCKFTA------DGSQADENCL-------------------------WVVPISVSTSKNPT 716

  Fly   761 NVSETLWM--QNVDVTFNVPENVKWIKVNAIQNGYYRVVYNDDNWASLIEEL--AANPNRFTSED 821
            .:::|..:  .:::||.:..:...|||:|....||||..|:.:    ::|:|  |.........|
  Fly   717 GIAKTFLLDKSSMEVTLDNVDEDDWIKINPGTVGYYRTRYSQE----MLEQLMPAVEKMELPPLD 777

  Fly   822 RLGMLSDAFTLCHANLLPCEITMNMIQYLPSETHYGPMALALRHLEKWRRILKYSECFLMLSEFI 886
            |||::.|.|.:..|........:.::....:||:|.........|.....::.:::.......|.
  Fly   778 RLGLIDDMFAMVQAGHASTADVLALVDSYRNETNYTVWTAITNSLTNLHILISHTDLMEDFHRFG 842

  Fly   887 KMKISTVMEKVGWS--DDGDVATRLLRPEVLLASVLWEDIDSITKAKNMLNQYLYYNGT-AIPPN 948
            :.....|..::||.  |..:....|||..||...|.:...|:|.:||....:::  ||| .:|.:
  Fly   843 RNLYEPVAYRLGWEPRDGENHLDTLLRSLVLTRLVSFRSSDTIEEAKIRFRRHV--NGTELLPAD 905

  Fly   949 LREVVYTGSILSGEYIYWQHCWERFVNLQRTSETFVERMQLLRALGRTKDAWLQNRLLSHV--TM 1011
            ||...|...:..|:    :..:...::|.|.::...|:.::.||||...|..|..|::...  :.
  Fly   906 LRTTCYKAVLQDGD----EKIFNEMLDLYRATDLHEEQDRISRALGCCGDLKLLRRVIDFAMSSE 966

  Fly  1012 LPTEEVVQVLKAIAGTPTGGAMACRFLQAKWFELEKRLGPGTISFAKVISAITQYGATKFDYDEL 1076
            :..::.|.|:.|:|..|.|..||..|.:....:|.:|...|.:     :|.:.:|....|..:|.
  Fly   967 VRAQDSVFVIVAVAINPKGRDMAWEFFKENNKQLLERYQGGFL-----LSRLIKYLIENFASEER 1026

  Fly  1077 KSLVHRFGRGHGMSVLNMTLS----SVASNVEWVARSQTSL 1113
            ...|..|.:.:.:.....|:|    ::..|..|:.|.:..|
  Fly  1027 AKEVEEFLQVNQIPGCERTVSQAVETIRLNAAWLQRDREQL 1067

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4467	NP_001036747.1	GluZincin	145..677	CDD:472708	131/542 (24%)
		ERAP1_C	783..1078	CDD:463368	72/301 (24%)
Psa	NP_728614.1	M1_APN-Q_like	227..662	CDD:341064	131/541 (24%)
		ERAP1_C	741..1055	CDD:463368	76/328 (23%)