Protein Alignment CG4467 and LOC3290884

DIOPT Version :10

• Sequence 1: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Sequence 2: XP_061503389.1
• Gene: LOC3290884 / 3290884
• VectorBaseID: AGAMI1_007830
• Length: 956
• Species: Anopheles gambiae
• Alignment Length: 1063
• Identity: 220/1063 - (20%)
• Similarity: 397/1063 - (37%)
• Gaps: 230/1063 - (21%)

  Fly   123 PIATNGEPFPWLEK-------------MLPTSVRPLRYMVTIHPNLTTLD---VKGQVTIDLHVE 171
            |:.....|...:||             :||....|:.|.:.:  ::|..|   ..|.|.|.....
Mosquito    14 PLILASAPVEIVEKVSTSRDAHDDSRYLLPKVSEPINYNLFL--DITNYDFYSYNGTVEITFRYT 76

  Fly   172 KETNFIVLHIQDLNVTEKAIVTPGPKGYALKIVKVLEFPPRQQLYIEVKERLKKKSNYTLNLRWY 236
            .:.|...|:...|.:..::|...||.|..:.:..|:.....:|:|...::||:....|.:.:.:.
Mosquito    77 GDQNHFYLNSDGLVIATESIKVTGPDGTDVPVANVIYMEEFEQIYFGFRDRLQTGEQYKIAISFL 141

  Fly   237 SKLNPEPEGFYVDQYESSNGVERLLAATVFRPNGARRAFPCFDEPHVRAPFRISVFRDRFHIGLS 301
            :.:..|.:|.|...|::.| ..|.||.|.|....||..|||:|||..:|.|.:.:.....:..||
Mosquito   142 NNIGTELKGLYRSSYKAGN-TTRYLATTHFESTYARSVFPCYDEPSYKATFNVKIRHRSEYRALS 205

  Fly   302 NSIVHTTEDVGFYMGTGLLRDDFIETPPLPADAVAWVVSDFQRESLQPSAAYIPTTPAPPGSGVG 366
            |.....:..||.|..|     .|..||.:....:|:|:|||:
Mosquito   206 NMPAINSVTVGDYTET-----TFDTTPLMSTYLLAFVISDFK----------------------- 242

  Fly   367 GKKSAQLNNYTQLKGKNPPVRNITALTHSLNVNLTPRQNLTVVQPTTTTAWPVNLNGNGKPSNLT 431
                                    .|:|
Mosquito   243 ------------------------TLSH------------------------------------- 246

  Fly   432 SLSQSTGSSIKRAPSYTFYAPRDLLIRSSFILHTSRDVLEYLQTWLDISYPLTKVDFVALPSLDR 496
                       .:..:..:|....:..:.:.|....:.|..|:.:....|.|.|||.:|:|....
Mosquito   247 -----------ESDRFRVFAAESKVAHTGYALEFLGNSLRTLENFFGRQYQLPKVDLIAIPDFAM 300

  Fly   497 NMISSLGLVTLKTSFLTDPSSITSEQ-YQFSALRIAEAMVRQFFGGITSRKVLKDVWLWEGLIQY 560
            ..:.:.||:|.:..:|.....:|:.: .|..|..|...:...:||...:.:....:||.||..:|
Mosquito   301 GAMENWGLITFREQYLIYEEGVTTARTKQNIADLITHELTHMWFGNEVTPEWWTYLWLSEGFARY 365

  Fly   561 LGIHALAPLQETWPLREMYLLKMATAALDIDAIQGWDSIMN--GTSHDGNNEEF---FVQKTAAI 620
            ...:..:.|:.||.|.:.:::....:||..|.... :.:|:  .|:....|:.|   ...|:|::
Mosquito   366 FEYYITSQLEPTWNLWQQFIVNNVHSALSQDCNSN-NRMMSYYATNPAVLNDLFDYVVYAKSASV 429

  Fly   621 FSMLHTAIGEDRFRGCLGSFLKVNRFRTAEPTDLWTICTK--KANGSKNIKDMMTLWTHQPGFPL 683
            ..|:...||.|.||..|..:|:...:.|..|..|:|...|  ..:...:::.:...|.:.||:|:
Mosquito   430 IRMIQNVIGFDTFRQSLNDYLRSRSYLTTRPQYLYTSIEKFRTVDLPASVEVIFESWANTPGYPV 494

  Fly   684 LTVT--KMGNSISISQRPFRPAEFLAIHDDSYDGNNYNKTTLNATDMPSTVATTTQGSKHKVAPH 746
            :||:  :...:::.||:.|.                          ||:.:.|..|        :
Mosquito   495 VTVSIDRTTRTLTASQKRFW--------------------------MPNEIDTPPQ--------N 525

  Fly   747 MKWIFPVTY------VTDINNVSETLWM--QNVDVTFNVPENVKWIKVNAIQNGYYRVVYNDDNW 803
            |.:..||.|      .||..:.:.|.|:  |:...|..:...|:|:.||..|.|||||.|:|::|
Mosquito   526 MLFYIPVNYGSNVPTSTDFEDTTPTFWLTPQDPTATVTLEAGVEWVVVNKQQTGYYRVNYDDESW 590

  Fly   804 ASLIEELAANPNRFTSE----DRLGMLSDAFTLCHANLLPCEITMNMIQYLPSETHYGPMALALR 864
            ..|||.|  |.::|..:    :|..::.|...|..|..:..::.::::|||..||.|.|.|.|..
Mosquito   591 HKLIEVL--NSDQFEDQLPVINRAQLVDDVANLARAGEVGYDVALSLMQYLERETEYIPWATAYN 653

  Fly   865 HLEKWRRILKYSECFLMLSEFIKMKISTVMEKVGWSDDGDVATRLLRPEVLLASVLWEDIDSITK 929
            .|....|:....|.:.....|::.....:.|.:..:...|..:||.|...:..:........:..
Mosquito   654 ALLYLDRMFSSHEEYSRFETFLRTITGCMYENILLTGPMDQISRLHRGNTVYLACYSGVKKCLDD 718

  Fly   930 AKNMLNQYLYYNGTAIPPNLREVV------YTGSILSGEYIYWQHCWERFVNLQRTSETFVERMQ 988
            |..:.|:.:..:...||..::..|      |..:.|:.:    ...:|::|    ||....|.:.
Mosquito   719 AHALANKAVQDSSFTIPEEVQASVFCALHKYPSATLNAQ----TDLFEKYV----TSANSPEDLD 775

  Fly   989 LLRALGRTKDAWLQNRLLSHVTMLPTEEVVQ-VLKAIA----GTP-TGGAMACRFL--------- 1038
            ::            ||.|:.|.....|.::: .|..:|    |.| |.|..:..:|
Mosquito   776 MI------------NRFLASVGCARNETIMEYYLTLLAYNYPGLPVTAGQRSQIYLGLINGSPGT 828

  Fly  1039 -QAKWFELEKRLGPGTISFAKVISAITQYG---ATKFDYDELKSLVHRFGRGH-----GMSVLNM 1094
             ||....|.:.....|.....|....|:.|   .|:..::.||::|..:  .|     ..:..:.
Mosquito   829 RQAALQYLYEHFSTVTYLLTSVTPIFTELGNRINTRLQHEVLKNIVDEY--RHMLTTAAKAAADA 891

  Fly  1095 TLSSVASNVEWVARSQTSLYKWV 1117
            .|.....|:.|:.:...|:..|:
Mosquito   892 ALVKAEQNIRWIEKHAESITSWL 914

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4467	NP_001036747.1	GluZincin	145..677	CDD:472708	109/542 (20%)
		ERAP1_C	783..1078	CDD:463368	73/323 (23%)
LOC3290884	XP_061503389.1	None