Protein Alignment CG4467 and CG2111

DIOPT Version :10

• Sequence 1: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Sequence 2: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Alignment Length: 990
• Identity: 219/990 - (22%)
• Similarity: 385/990 - (38%)
• Gaps: 220/990 - (22%)

  Fly   138 LPTSVRPLRYMVTIHPNLTTLD-----VKGQVTIDLHVEKETNFIVLHIQDLNVTEKAIVTPGPK 197
            ||..:.||.|.|.|   :|.::     ..|.|.|||..|:.|..|||:..||.:.::..||...|
  Fly    26 LPKWLVPLSYRVDI---VTRINQPYQPFGGTVVIDLRSERSTKRIVLNAHDLAIGKRRAVTLSDK 87

  Fly   198 -GYALKIVKVLEFPPRQQLYIEVKERLKKKSNYTLNLRWYSKLNPEPEGFYVDQYESSN-GVERL 260
             |.::.:..:.......:|.:.:|..||....|::.:.:.|.|..:..|||...|...| .:.:.
  Fly    88 NGNSVPVSSIQMDIKLSRLTVSLKRPLKVNVTYSMRVAFTSVLRNDNTGFYSSNYVDHNTTLTQW 152

  Fly   261 LAATVFRPNGARRAFPCFDEPHVRAPFRISVFRDRFHIGLSNSIVHTTEDVGFYMGTGLLRD--- 322
            ||||.|.||.||.||||||:|..|.||:|::.....:..|||..|..|      :....|:|
  Fly   153 LAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQRT------IRHASLKDYVW 211

  Fly   323 -DFIETPPLPADAVAWVVSDFQRESLQPSAAYIPTTPAPPGSGVGGKKSAQLNNYTQLKGKNPPV 386
             .|:|:.|:....||:::|.|.|                ||             :|..:..:.|:
  Fly   212 TQFVESHPMQTYLVAFMISKFDR----------------PG-------------FTSSERSDCPI 247

  Fly   387 RNITALTHSLNVNLTPRQNLTVVQPTTTTAWPVNLNGNGKPSNLTSLSQSTGSSIKRAPSYTFYA 451
                                        :.|       .:|.   :|||:..:::..||..:||
  Fly   248 ----------------------------STW-------ARPD---ALSQTEFANMVVAPLLSFY- 273

  Fly   452 PRDLLIRSSFILHTSRDVLEYLQTWLDISYPLTKVDFVALPSLDRNMISSLGLVTL-KTSFLTDP 515
             .||                     .:.:|...|:|.||||........:.||... :.|.|.|.
  Fly   274 -EDL---------------------FNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDS 316

  Fly   516 SSITSEQYQFSALRIAEAMVRQFFGGITSRKVLKDVWLWEGLIQYL---GIHALAPLQETWPLRE 577
            ...:.:..|..|..:|..:|.|:||.:.|.....::||......||   |:|:|.|   .|..:|
  Fly   317 QRSSIDDQQGVARAVAMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRP---EWDYQE 378

  Fly   578 MYLLKMATAALDIDAIQGWDSIMNGTSHDGN----NEEFFVQKTAAIFSMLHTAIGEDRFRGCLG 638
            .:.|::..:.||.||....|.:......:.:    ..|...:|.|.:|.|||..:||:.:...|.
  Fly   379 RHALQLYLSVLDYDAHVNTDLVTASVPDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALR 443

  Fly   639 SFLKVNRFRTAEPTDLWTICTKKA--NG----SKNIKDMMTLWTHQPGFPLLTVTKMGNSISISQ 697
            .:|.|...|||..:|.|.:...:.  ||    ..||..:|..|..|||:||:|||:
  Fly   444 RYLVVYANRTATSSDFWDLLQLQVDRNGRLGKGLNITRIMKCWLGQPGYPLVTVTR--------- 499

  Fly   698 RPFRPAEFLAIHDDSYDGNNYNKTTLNATDMPSTVATTTQGSKHKVAPHMKWIFPVTYV------ 756
                               ||:..|...:.....:   |...:::.|.:..|..|::|.
  Fly   500 -------------------NYDHRTAIVSQQRFFI---TPQFRNRWARNPCWWVPLSYTCPSCQH 542

  Fly   757 TDI--------------NNVSETLWMQNVDVTFNVPENVKWIKVNAIQNGYYRVVYNDDNWASLI 807
            ::|              ::.|.|:.::.::.     |...||..|......:||.|:..|| .|:
  Fly   543 SEIISFSRWLTCPTSKPSSKSNTVLLEKLEA-----EPTDWILFNVQHTAPFRVNYDLRNW-QLL 601

  Fly   808 EELAANPNRFT---SEDRLGMLSDAFTLCHANLLPCEITMNMIQYLPSETHYGPMALALRHLEKW 869
            .:..|:||:|.   ..:|..::.|.|:|..:..:..::.:.::.||..|..:..........|:.
  Fly   602 NKTLADPNKFRLIHRVNRAQLVDDLFSLAWSGDIEYDMALGILGYLEHEDEFVVWVATEISFERI 666

  Fly   870 RRILKYSECFLMLSEFIKMKISTVMEKVGWSD----DGDVATRLLRPEVLLASVLWEDIDSITKA 930
            ..:.|.:..:|:...::::.:....::|..||    .|::..   ||.::..:..:|....::.|
  Fly   667 NNVAKSNPNYLIFKTYMRLLLERQFKRVISSDLTSSSGNMTH---RPVIIRLACEYELPACVSLA 728

  Fly   931 KNMLNQYLYYNGTAIPPNLREVVYTGSILSG--------EYIYWQHCWERFVNLQRTSETFVERM 987
            :....:.....|..:....||.|...::..|        |.:|            :.|....|:.
  Fly   729 RREFMKGTPEKGGWMTIRERETVVCTAVKFGTEGDRDMVESMY------------KRSNFAAEKE 781

  Fly   988 QLLRALGRTKDAWLQNRLL---SHVTMLPTEEVVQVLKAIAGTPTGGAMACRFLQAKWFELEKRL 1049
            .||.||..:::.:...|:|   ...:.:..:...:..||:.....|..:|.:::......:....
  Fly   782 SLLTALACSRNVFALQRVLIWTFESSGVRKQNARRTFKAVVSNSMGYRLAKKYVSVNMQNIRNYC 846

  Fly  1050 GPGTISFAKVISAIT 1064
            ...|   .||::.:|
  Fly   847 SNST---DKVVNLMT 858

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4467	NP_001036747.1	GluZincin	145..677	CDD:472708	142/556 (26%)
		ERAP1_C	783..1078	CDD:463368	54/300 (18%)
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	141/555 (25%)
		ERAP1_C	578..897	CDD:463368	54/300 (18%)