Protein Alignment CG4467 and Aopep

DIOPT Version :10

• Sequence 1: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Sequence 2: XP_008769651.1
• Gene: Aopep / 290963
• RGDID: 1309592
• Length: 886
• Species: Rattus norvegicus
• Alignment Length: 845
• Identity: 166/845 - (19%)
• Similarity: 272/845 - (32%)
• Gaps: 260/845 - (30%)

  Fly     9 GNMSKRDY--------KVATTDGIELEPLGGEKCDKDKDKDKEKQTNGVTFGGESSGGRQTRTGV 65
            |:..|..|        |.|..|...||.:....||..| ......|..:...       .:|..:
  Rat    20 GSCGKTTYASGCFLFGKPAICDSELLEEIRSLSCDSAK-LPTANYTMDINLD-------PSRDDL 76

  Fly    66 AVCSQRRALLVAGIVL------GSLLLTAIIIAYAGPQNDCSCGSKTVSGYETDEENNTQPFNPI 124
            .:.:....|||...||      ||.:|...|:.:.|..|.|.  .::.|..||.:..:.:.:  |
  Rat    77 PLMANTSHLLVKHYVLDLDVDFGSRVLEGNIVLFFGDGNRCK--KQSSSSQETFQMESEEAY--I 137

  Fly   125 ATNGEPFPWLEKMLPTSVRPL---RYMVTI-------------HPN------------------- 154
            ....||. .:.||...:..|.   |.....             |.|
  Rat   138 LRTAEPC-HVPKMDSNTFSPKMGHREFAVFGKSDQDAFDNDGNHDNKEHDSESSSSKYCCDTGNH 201

  Fly   155 -----LTTLDVKGQVTIDLHVEKETNFIVLHIQDLNVTEKA-IVTPGPKGYALKIVKVLEFPP-- 211
                 |..||     ..||.|.|.....|..:.||....|| .:|..|:....:||:.|...|
  Rat   202 GREDFLLVLD-----CCDLSVLKVEEVDVAAVPDLEKFTKAPNLTAAPEKRRCEIVRDLVALPAD 261

  Fly   212 --RQQLYIEVK--------ERLKKKSNYTLNLR----------------WYSKLNPEPEGFYVDQ 250
              |:||....:        |.|.....::|.:|                ||   ..:|||..|..
  Rat   262 AWREQLDCYTRCSQAPGCGELLFDSDKWSLQIRKKGVPTAADFPHAIRIWY---KTKPEGQSVTW 323

  Fly   251 YESSNGVERLLAATVFRPNGARRAFPCFDEPHVRAPFRISVFRDRFHIGLSNSIVHTTEDVGFYM 315
            ....:|  |....|:..|...|..||| .||    |..:|.::.......|..::.:.|...
  Rat   324 TSDQDG--RPCVYTMGSPINNRALFPC-QEP----PVAMSTWQATVRAAASFVVLMSGEKSA--- 378

  Fly   316 GTGLLRDDFIETPPLPADAVAWVVSDFQRESLQPSAAYIPTTPAPPGS---GVGGKKSAQLNNYT 377
                      :..||....::|              .|..|.|.|..:   .||        .:|
  Rat   379 ----------KPTPLREGYMSW--------------HYYVTMPMPASTFTIAVG--------CWT 411

  Fly   378 QLKGKNPPVRNITALTHSLNVNLTPRQNLTVVQPTTTTAWPVNLN---GN-----GKPSNLTSLS 434
            ::|.|..|:.::|  .|:|.:.                  |.:.:   ||     ..|....|.|
  Rat   412 EMKPKTSPLDDLT--EHTLPLR------------------PSDADFRYGNTCSHMEYPCRFQSAS 456

  Fly   435 QSTGSSIKRAPSYTFYAPRDL----------LIRSSFILHTSRDVLEYLQTWLDISYPLTKVDFV 489
            .:|.:.|    .|..:||..|          ||.|  .|..:..||.        ::|.:::|.:
  Rat   457 AATQNII----PYRVFAPVCLEGACREALLWLIPS--CLSAAHSVLG--------THPFSRLDIL 507

  Fly   490 ALPSLDRNMISSLGLVTLKTSFLTDPSSITSEQYQFSALRIAEAMVRQFFGGITSRKVLKDVWLW 554
            .:|:    ...|||:.:....||:. |::|...: ....|:...:...:||.....:...:.||.
  Rat   508 IVPT----NFPSLGMASPHIIFLSQ-STLTGTSH-LCGTRLCHEIAHAWFGLAIGARDWTEEWLS 566

  Fly   555 EGLIQYLGIHALAPLQETWPLREMYLLKMATAALDIDAIQGWDSIMNG-------------TSH- 605
            ||...:|.....|..|:. |..|....:...|.|....:|  |.:.|.             |.|
  Rat   567 EGFATHLEDIFWAEAQQL-PPHEALEQQELRACLRWHRLQ--DELQNSPEGMQVLRPNKEKTGHV 628

  Fly   606 ---------DG-NNEEFFVQ----KTAAIFSMLHTAIGEDRFRGCLGSFLKVNRFRTAEPTDLWT 656
                     :| |.|:.|:|    |...:...|...:||:.:...|..|:.:...:.....|...
  Rat   629 SASGASVVKNGLNPEKGFMQVHYLKGYFLLRFLARTLGEETYFPFLRKFVHLFHGQLILSQDFLQ 693

  Fly   657 ICTKKANGSK----NIKDMMTLWTHQPGFPLL--------------TVTKMGNSIS----ISQRP 699
            :..:....:|    ::::::..|...||.|..              .|.::|:.::    :::||
  Rat   694 MLLESIPENKRFGLSVENIVGDWLECPGIPKALQEERKAKDCSPSRLVRQVGSEVAKWIRVNRRP 758

  Fly   700  699
              Rat   759  758

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4467	NP_001036747.1	GluZincin	145..677	CDD:472708	125/653 (19%)
		ERAP1_C	783..1078	CDD:463368
Aopep	XP_008769651.1	GluZincin	<308..704	CDD:472708	95/483 (20%)
		Leuk-A4-hydro_C	773..885	CDD:462686