Protein Alignment CG4467 and Y42A5A.1

DIOPT Version :10

• Sequence 1: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Sequence 2: NP_505820.1
• Gene: Y42A5A.1 / 179536
• WormBaseID: WBGene00012776
• Length: 1045
• Species: Caenorhabditis elegans
• Alignment Length: 1054
• Identity: 199/1054 - (18%)
• Similarity: 365/1054 - (34%)
• Gaps: 275/1054 - (26%)

  Fly    26 LEPLGGEKCDKDKDKDKEKQ---TNGVTFGGESSGGRQTRTGVAV-----------CSQRRALLV 76
            :.|...|:|.:....:..:.   ::.||    :|....:.|.||.           ||.|.  |.
 Worm    16 ISPFALEECRQGTSSEPGRMRPFSDAVT----ASASTTSTTAVATTVTSEQRQQSCCSARP--LA 74

  Fly    77 AGIVLGSLLLTAIIIAYAGPQNDCSCGSKT----VSGYETDEENNTQPFNPIATNGEPF------ 131
            .|:|..|:....|......|.......|::    .|...|..:.::..| ||.||....
 Worm    75 IGVVAVSMSFALIYFFMIVPLTSSILPSQSSPILPSDISTIYQKSSTDF-PIFTNSTELITTTED 138

  Fly   132 PWLEKMLPTSVR--------PLRYMVTI------HPNLT----TLDVKGQVTID----------L 168
            |....:..|:.|        ||.|.|.:      .|.::    ...|||.|.:.          |
 Worm   139 PLYVHINNTNHRLQIPQIHIPLLYEVELKLFVPWRPTISFGSDNFSVKGHVRVHFTSGGGSRILL 203

  Fly   169 HVEKETNFIVLHIQDL--------NVTEKAIVTPGPKGYALKIVKVLEFPPRQQLYIEVKERLKK 225
            |.:.:.     ||.|.        |:|.|.:    .:.|:            |.|.:.::..:..
 Worm   204 HSDSKQ-----HIGDCVVRDELNRNITVKLV----GRQYS------------QILDLNLETDMIH 247

  Fly   226 KSNYTLNLRWYSKLNPE-PEGFYVDQYESSNGVERLLAATVFRPNGARRAFPCFDEPHVRAPFRI 289
            ..||||::.:.|.:|.. ..|.:...|...|.. |.:.||..:.:.||..|||.|.|.::|.|..
 Worm   248 GMNYTLDVAFKSAINLNLAYGLFAAPYTFENET-RYVVATQLQISEARTVFPCIDVPDMKAQFDT 311

  Fly   290 SVFRDRFHIGLSNSIVHTTEDVGFYMGTGLLRDDFIETPPLPADAVAWVVSDFQRESLQPSAAYI 354
            .:........::|.:.::|:..|.:..|     .|..|||:.....|:.|||:         .|:
 Worm   312 VIIHPTGTTSIANMMENSTKVDGEWTTT-----TFHRTPPMSTYLFAFSVSDY---------PYL 362

  Fly   355 PTTPAPPGSGVGGKKSAQLNNYTQLKGKNPPVRNITALTHSLNVNLTPRQNLTVVQPTTTTAWPV 419
            .|
 Worm   363 ET--------------------------------------------------------------- 364

  Fly   420 NLNGNGKPSNLTSLSQSTGSSIKRAPSYTFYAPRDLLIRSSFILHTSRDVLEYLQTWLDISYPLT 484
             .:|.|..|.:                   |.....|:.:..|..:...||::.:.:..|.|||.
 Worm   365 -FSGRGVRSRV-------------------YCDPTKLVDAQLITKSIGPVLDFYEDYFGIPYPLE 409

  Fly   485 KVDFVALPSLDRNMISSLGLVTLK--TSFLTDPSSITSEQYQFSALRIAEAMVRQFFGGITSRKV 547
            |:|.|.:|:|....:.:.||:|::  ....|:.....|:::....: :|..:..|:||.:.:.|.
 Worm   410 KLDVVIVPALSVTAMENWGLITIRQTNGLYTEGRFAISQKHDVQEI-VAHELAHQWFGNLVTMKW 473

  Fly   548 LKDVWLWEGLIQYLGIHALAPLQETWPLREMYLLKMATAALDIDAIQGWDSIMNGTSHDGNNEEF 612
            ..|:||.||....:.:.|:..|:.|....|....:....||..|.|   |||...:....:|.:.
 Worm   474 WNDLWLNEGFATLISVRAVDFLENTTWRYEDSSAESQCVALRADQI---DSISPVSGKKNSNFDS 535

  Fly   613 FVQ---------KTAAIFSMLHTAIGEDRFRGCLGSFLKVNRFRTAEPTDLWTICT----KKANG 664
            :::         |:|.|..|:...:.||.||..|..||....::.|:..||:.:..    ..|.|
 Worm   536 YMEIQGKAIIYKKSAIIIRMIERLVEEDIFRQGLKRFLNTFLYKNADHEDLFNVLVYVHDSSAGG 600

  Fly   665 -----SKNIKDMMTLWTHQPGFPLLTVT-KMGNSISISQRPFRPAEFLAIHDDSYDGNNYNKTTL 723
                 :.::.|:|..|..|..||::.|. |.|:.:::.|..:...
 Worm   601 HLRGQNFSLSDVMDTWIRQAHFPVIHVNRKEGSLVTLRQEKYEHV-------------------- 645

  Fly   724 NATDMPSTVATTTQGSKHKVAPHMKWIFPVTYVTDINNVSETLWMQNVDVTFNVPENVKWIKVNA 788
             ..|.|.               ...|..|:.|...::...:..|:  .|....|.:....:.|:.
 Worm   646 -PRDEPE---------------KQVWKIPIFYDDPVSGKHKVFWL--TDTQPKVFDMGGLLVVDP 692

  Fly   789 IQNGYYRVVYNDDNWASLIEELAANPNRFTSEDRLGMLSDAFTLCHANLLPCEITMNMIQYLPSE 853
            .|..|.|:.|:.:.::.:...|..:.....:..|..::.|...:.....|..::..|:..|:..|
 Worm   693 HQLTYMRLRYDMEMYSDITMALMDDFTMIPTNSRSRLIDDTLAMAENGQLTYKVPFNLTMYMSRE 757

  Fly   854 THYGPMALALRHLEKWRRILKYSECFLMLSEFIKMKISTVMEK-------VGWSDDGDV-ATRLL 910
            ..|.|......:|:.:...:...|.:.:..:::::.:....:|       |.:..:.|: .||.:
 Worm   758 IAYRPFQTFSAYLDFFLPRMYIHEGWSIYKKYLELVVGIPFDKFNAEGLDVSFDHNTDLFHTRQI 822

  Fly   911 ----------RPEVLLASVLWEDIDSITKAKNMLNQYLYYNGTAIPPNLREVVYTGSILSG---- 961
                      .|.|.:|...:.::......:|.|...:..|  .||..||..||:.:|..|
 Worm   823 VVFRACGIEYEPCVRMAKQRFAELRVNCSGENQLLSGMECN--KIPYYLRPHVYSAAINDGTQED 885

  Fly   962 -EYIYWQHCWERFV 974
             :::|.:...|.::
 Worm   886 FDFLYKKWMIEHYM 899

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4467	NP_001036747.1	GluZincin	145..677	CDD:472708	117/580 (20%)
		ERAP1_C	783..1078	CDD:463368	37/215 (17%)
Y42A5A.1	NP_505820.1	M1_APN-Q_like	160..618	CDD:341064	117/580 (20%)
		ERAP1_C	687..>939	CDD:463368	37/215 (17%)