Protein Alignment CG4467 and Lta4h

DIOPT Version :10

• Sequence 1: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Sequence 2: NP_032543.2
• Gene: Lta4h / 16993
• MGIID: 96836
• Length: 611
• Species: Mus musculus
• Alignment Length: 702
• Identity: 115/702 - (16%)
• Similarity: 212/702 - (30%)
• Gaps: 264/702 - (37%)

  Fly   157 TLDVKGQVTIDLHVEKETNFIVLHIQDLNVTEKAIVTPGPKGYALKIVKVLEFPPRQQLYIEVKE 221
            |||.|     ||.:||    :|::.|::..|...  :.|.||..::|...:.....|::.||:..
Mouse    54 TLDTK-----DLTIEK----VVINGQEVKYTLGE--SQGYKGSPMEISLPIALSKNQEIVIEISF 107

  Fly   222 RLKKKSNYTLNLRWYSKLNPEPEGFYVDQYESSNGVERLLAATVFRPNGARRAFPCFDEPHVRAP 286
            ....||:   .|:|   |.|          |.::|.:.....:..:....|...||.|.|.|:..
Mouse   108 ETSPKSS---ALQW---LTP----------EQTSGKQHPYLFSQCQAIHCRAILPCQDTPSVKLT 156

  Fly   287 FRISVFRDRFHIGLSNSIVHTTEDVGFYMGTGLLRDD--------------FIETPPLPADAVAW 337
            :...|...:..:.|.::|                ||.              |.:..|:|...:|.
Mouse   157 YTAEVSVPKELVALMSAI----------------RDGEAPDPEDPSRKIYRFNQRVPIPCYLIAL 205

  Fly   338 VVSDFQRESLQPSAAYIPTTPAPPGSGVGGKKSAQLNNYTQLKGKNPPVRNITALTHSLNVNLTP 402
            |                          ||..:|.|:...|.:..:...|..
Mouse   206 V--------------------------VGALESRQIGPRTLVWSEKEQVEK-------------- 230

  Fly   403 RQNLTVVQPTTTTAWPVNLNGNGKPSNLTSLSQSTGSSIKRAPSYTFYAPRDLLIRSSFILHTSR 467
                             :.|...:..::..:::..|...       .:...|||:
Mouse   231 -----------------SANEFSETESMLKIAEDLGGPY-------VWGQYDLLV---------- 261

  Fly   468 DVLEYLQTWLDISYPLTKVDFVALPSLDRNMISSLGLVTLKTSFLTDPSSITSEQYQFSALRIAE 532
                     |..|:|...::...|                  :|:| |:.:..::...:.  ||.
Mouse   262 ---------LPPSFPYGGMENPCL------------------TFVT-PTLLAGDKSLSNV--IAH 296

  Fly   533 AMVRQFFGGITSRKVLKDVWLWEGLIQYLGIHALAPLQETWPLREMYLLKMATAALDIDAIQGWD 597
            .:...:.|.:.:.|.....||.||...||..|....|             .........|:.||.
Mouse   297 EISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRL-------------FGEKFRHFHALGGWG 348

  Fly   598 SIMNGTSHDGNNEEF--------------------FVQKTAAIFSMLHTAIGEDRFRGCLGSFLK 642
            .:.|.....|.:..|                    :.:..|.:|.:.....|.:.|.|.|.:::|
Mouse   349 ELQNTIKTFGESHPFTKLVVDLKDVDPDVAYSSIPYEKGFALLFYLEQLLGGPEVFLGFLKAYVK 413

  Fly   643 VNRFRTAEPTDLWTICTKKANGSKNIKDMMTL--------WTHQPGFPLLTVTKMGNSISISQRP 699
            ...:::. .||.|     |:....:.||.:.|        |.:.||.|                |
Mouse   414 KFSYQSV-TTDDW-----KSFLYSHFKDKVDLLNQVDWNTWLYAPGLP----------------P 456

  Fly   700 FRPAEFLAIHDDSYDGNNYNKTTLNA-------------TDMPS-TVATTTQGSKHKVAPHMKWI 750
            .:|              ||:.|..||             .|:.| ::|.....|.|::...:..:
Mouse   457 VKP--------------NYDVTLTNACIALSQRWVTAKEEDLSSFSIADLKDLSSHQLNEFLAQV 507

  Fly   751 -----FPVTYVTDINNVSETLWMQNVDVTFNVPENVKWIKVNAIQNGYYRVV 797
                 .|:.::..:..|.....:.|.::.|      :|::: .||:.:...:
Mouse   508 LQKAPLPLGHIKRMQEVYNFNAINNSEIRF------RWLRL-CIQSKWEEAI 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4467	NP_001036747.1	GluZincin	145..677	CDD:472708	93/561 (17%)
		ERAP1_C	783..1078	CDD:463368	3/15 (20%)
Lta4h	NP_032543.2	leuko_A4_hydro	6..608	CDD:274120	115/702 (16%)