Protein Alignment CG4467 and LOC1273751

DIOPT Version :10

• Sequence 1: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Sequence 2: XP_003436384.2
• Gene: LOC1273751 / 1273751
• VectorBaseID: AGAMI1_009321
• Length: 1054
• Species: Anopheles gambiae
• Alignment Length: 1167
• Identity: 276/1167 - (23%)
• Similarity: 460/1167 - (39%)
• Gaps: 230/1167 - (19%)

  Fly    47 NGVT------FGGESSGGRQTRTGVAVCSQRRALLVAG---IVLGSLLLTAIII------AYAGP 96
            :|:|      |.|.:....|.|..:.:.|    ||.|.   .||...||||:::      |.||.
Mosquito    17 SGMTIRPTAHFAGSAPDREQRRRSIVILS----LLAACAFLFVLSLCLLTALVLVGRNLSADAGS 77

  Fly    97 QNDCSCGSKTV-------------------SGYETDEENNTQPFN-------------------P 123
            .:..:..|...                   :|.|..|..|...:|                   |
Mosquito    78 HSQLTVASDDKQHLFINNNHIDHDGDDGDDAGEEERERTNEPQYNRSTIFLPNSVFNTSAAPPPP 142

  Fly   124 IATNGEPFPW-------------LEKM---LPTSVRPLRYMVTIHPNLTTLDVKGQVTIDLHVEK 172
            :|.:....|.             .|::   ||..:||:.|.:.:.|:|......|:|.|:|:|.:
Mosquito   143 VAVSPGTGPTGRMNRVFKMGTQVAERLGFRLPRHIRPVHYELWLQPDLQRETFSGRVGIELNVSE 207

  Fly   173 ETNFIVLHIQDLNVTEKAIVTPGPKGYALKIVKVLEFPPRQQLYIEVKERLKKKSNYTLNLRWYS 237
            .||:||||.:.|::||..:.|.|.....:.|.:..|.|..:...||.:..:...: |.|::::..
Mosquito   208 STNYIVLHSKKLSITETVLRTLGTGPEEVTIARAYELPEHEYWVIETQGEIGAGA-YRLSVQFNG 271

  Fly   238 KLNPEPEGFYVDQY-ESSNGVERLLAATVFRPNGARRAFPCFDEPHVRAPFRISVFRDR--FHIG 299
            .|.....|||..:| :.:....|.:|.:.|.|..||:|||||||||::|.:.|.:....  .:..
Mosquito   272 SLADRIIGFYSSKYLDKTTNRTRTIATSKFEPTFARQAFPCFDEPHLKAEYTIHMVHPSGDGYAA 336

  Fly   300 LSNSIVHTTEDVGFYMGTGLLRDDFIETPPLPADAVAWVVSDFQRESLQPSAAYIPTTPAPPGSG 364
            |||  ::..|.|......||....|..:..:....|.::||||    |......:|.
Mosquito   337 LSN--MNVKETVADKPSAGLSTTTFERSVSMSTYLVVFIVSDF----LHQEVLIVPE-------- 387

  Fly   365 VGGKKSAQLNNYTQLKGKNPPVRNITALTHSLNVNLTPRQNLTVVQPTTTTAWPVNLNGNGKPSN 429
                           .|.:.|:|          |..||.|     |..|
Mosquito   388 ---------------HGSSFPLR----------VYATPFQ-----QENT---------------- 406

  Fly   430 LTSLSQSTGSSIKRAPSYTFYAPRDLLIRSSFILHTSRDVLEYLQTWLDISYPLTKVDFVALPSL 494
                                          ::.|.|:|.:::|...:..|:|||.|:|..|:|..
Mosquito   407 ------------------------------AYALATARTIIQYYVKYFGIAYPLPKLDMAAIPDF 441

  Fly   495 DRNMISSLGLVTLK-TSFLTDPSSITSEQYQFSALRIAEAMVRQFFGGITSRKVLKDVWLWEGL- 557
            ....:.:.||||.: ||.|.:..:.::...|..|..||..:...:||.:.:.|...::||.||.
Mosquito   442 VSGAMETWGLVTYRETSILYNSVTSSTANKQRVAGVIAHELAHMWFGNLVTMKWWNELWLNEGFA 506

  Fly   558 --IQYLGIHALAPLQETWPLREMYLLKMATAALDIDAIQGWDSIMNGTSHDGNNEEFF----VQK 616
              |:|.|:.|..|   .|.:.|.:::......|::||..|...|:....:.....|.|    ..|
Mosquito   507 SYIEYKGMDAAHP---DWGIEEQFIIDDLHGVLNLDATLGSHPIVMSVENPNQITEIFDTITYSK 568

  Fly   617 TAAIFSMLHTAIGEDRFRGCLGSFLKVNRFRTAEPTDLWTICTKKANGSKNIKDMMTLWTHQPGF 681
            .|::..||...:....|:..:..:|:...:..:...||.....:.. ...::..:|..:|.|.|.
Mosquito   569 GASVIRMLEDFVTPPVFQQGVKRYLEKLAYANSVSEDLMRELDELV-PDVSVTGVMDTFTRQKGL 632

  Fly   682 PLLTVTKMGNSISISQRPFRPAEFLAIHDDSYDGNNYNKTTLNATDMPSTVATTTQGSKHKVAPH 746
            |::||.:  |::   |...|...|||..|                      |..|:.|.:    .
Mosquito   633 PVVTVAE--NAL---QYVLRQQRFLADQD----------------------ANETEESPY----G 666

  Fly   747 MKWIFPVTYVTDINN----VSETLWMQN----VDVTFNVPENVKWIKVNAIQNGYYRVVYNDDNW 803
            .:|..|:||:...::    ....:|..|    .::..:.|....|||:|..|.|||||.|....|
Mosquito   667 YRWYIPITYLASTDDPATAAPRRIWFPNDASRPELVIDKPAGSSWIKLNYRQIGYYRVNYPIAMW 731

  Fly   804 ASLIEELAANPNRFTSEDRLGMLSDAFTLCHANLLPCEITMNMIQYLPSETHYGPMALALRHLEK 868
            ....|.|....|.||..||.|:|:|||.|..|:||.....:.:.:||..||.|.|.:.....|:.
Mosquito   732 QQFGEALRKEVNTFTIGDRTGLLNDAFALADASLLAYNHALELTRYLSGETEYVPWSAIASKLKN 796

  Fly   869 WRRILKYSECFLMLSEFIKMKISTVMEKVGWS--DDGDVATRLLRPEVLLASVLWEDIDSITKAK 931
            .|.:|...:.:..::.:.:..:...::.|||.  .:|...|.|||..:|..:..:.....:.:|.
Mosquito   797 IRNLLYNYQSYDDITTYTQTLVDAAVKSVGWDVPAEGGHMTNLLRTTILDLACSFGHPACLEEAS 861

  Fly   932 NMLNQYLYYNGTAIPPNLREVVYTGSILSGEYIY-WQHCWERFVNLQRTSETFVERMQLLRALGR 995
            .....:| .:|..|.|:||.||||..|.||..:. |....|||    |......|:.:|:.||..
Mosquito   862 KQFRGWL-NDGAVIHPDLRSVVYTYGIQSGVTVADWDKVLERF----RQENDANEKTKLMVALAS 921

  Fly   996 TKDAWLQNRLLS---HVTMLPTEEVVQVLKAIAGTPTGGAMACRFLQAKWFELEKRLGPGTISFA 1057
            ..|.....|.|.   ...::.|::.:..::.||....|...|...::..|..|..|.|.|..:..
Mosquito   922 YPDQRTMRRFLDLSWDTALVRTQDQLSCIQYIAANRAGEQAAWEHVRENWPRLVARFGIGERNLG 986

  Fly  1058 KVISAITQYGATKFDYDELKSLVHRFGR-GHGMSVLNMTLSSVASNVEWVARSQTSLYKWVE 1118
            ::|.::|....|:....||:....|:.. |.|.:.....|.::.:|:.|:.|::.::..|::
Mosquito   987 RMIPSVTGRFTTQARLTELEDFFARYPESGAGATARRQALENIQNNISWLERNEANVAAWLK 1048

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4467	NP_001036747.1	GluZincin	145..677	CDD:472708	125/542 (23%)
		ERAP1_C	783..1078	CDD:463368	87/300 (29%)
LOC1273751	XP_003436384.2	None