Protein Alignment fzo and rdcA

DIOPT Version :10

• Sequence 1: NP_732840.1
• Gene: fzo / 42745
• FlyBaseID: FBgn0011596
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_418533.1
• Gene: rdcA / 948620
• ECOCYCID: EG11210
• Length: 742
• Species: Escherichia coli
• Alignment Length: 735
• Identity: 126/735 - (17%)
• Similarity: 254/735 - (34%)
• Gaps: 256/735 - (34%)

  Fly    82 LSRDRMKVAFFGRTSNGKSAVINALLHEKILPSA-----------------------MGHTTSCF 123
            :||..|.:|..|....|||..|||::..::||:.                       ..|.....
E. coli    65 ISRLEMVLAIVGTMKAGKSTTINAIVGTEVLPNRNRPMTALPTLIRHTPGQKEPVLHFSHVAPID 129

  Fly   124 CQVQ--------ANGSNETEHVKVEQEDEHM-------------------------ELSALSQLA 155
            |.:|        .:..:.|:.::::::...:                         .|:.|.:||
E. coli   130 CLIQQLQQRLRDCDIKHLTDVLEIDKDMRALMQRIENGVAFEKYYLGAQPIFHCLKSLNDLVRLA 194

  Fly   156 SA-------HSPGALKPSTLLQVNMAKNRCSILDY--DVVLMDTPGVDVTAQ--LDDCLDSYCMD 209
            .|       .:..|::...:::|... :...:..|  .:.|:||||.:...|  |...|:.....
E. coli   195 KALDVDFPFSAYAAIEHIPVIEVEFV-HLAGLESYPGQLTLLDTPGPNEAGQPHLQKMLNQQLAR 258

  Fly   210 ADVFILVLNAESTVSRVERQFFKDVASKLSRPNLFILNNRWDKASSLEPEMEQ---KVKDQHMER 271
            |...:.||:.....|..:.:..:.:.:......|::|.|::|:......:.:|   .:....|:.
E. coli   259 ASAVLAVLDYTQLKSISDEEVREAILAVGQSVPLYVLVNKFDQQDRNSDDADQVRALISGTLMKG 323

  Fly   272 CVNLLVDELGVYSTAQEAWERIYHVSAL------EALH--IRNGQITNPSGQTQQRY-------- 320
            |:           |.|:    |:.||::      .|.:  ..||::..|.   |||:
E. coli   324 CI-----------TPQQ----IFPVSSMWGYLANRARYELANNGKLPPPE---QQRWVEDFAHAA 370

  Fly   321 ------------QEFLRFEND-------------------FSNCLAVSALKTKFGPHLLSAQKIL 354
                        .|.:|...|                   ::|. ::.||::       :|.|:|
E. coli   371 LGRRWRHADLADLEHIRHAADQLWEDSLFAQPIQALLHAAYANA-SLYALRS-------AAHKLL 427

  Fly   355 NQLKS------------TLICPFIEKVSRLIDENKE----RRANLNAEIEDWLIL--------MQ 395
            |..:.            .:.|..:.:....|:|:.:    .:|.::.||:..:.|        ::
E. coli   428 NYAQQAREYLDFRAHGLNVACEQLRQNIHQIEESLQLLQLNQAQVSGEIKHEIELALTSANHFLR 492

  Fly   396 EDREALQY----CFEELTEMTQRV-GRCVLNDQIKTLIPSSVLSFSQPFHPEFPAQIGQYQRSLC 455
            :.::||:.    .|::.:|....: .||      :||:.::..:.|:    :|..:..:.:.:||
E. coli   493 QQQDALKVQLAALFQDDSEPLSEIRTRC------ETLLQTAQNTISR----DFTLRFAELESTLC 547

  Fly   456 AHLDKLLEDRVLQCLSIPLQRKILDIEKEIGLPIAENSCDWQLIYGLDCQSYMSDFQPDLRFRFS 520
                     |||..:..|       ||:::.:.::|                 |.|:|...|...
E. coli   548 ---------RVLTDVIRP-------IEQQVKMELSE-----------------SGFRPGFHFPVF 579

  Fly   521 LG----------FTALWHRLEGNLPLHASPFRIQKLQNGHKKCSPLPPLVNGNHWQMLESLVKSK 575
            .|          |:.:..|.|..   .....|:..::....:....|....||.....|::..|
E. coli   580 HGVVPHFNTRQLFSEVISRQEAT---DEQSTRLGVVRETFSRWLNQPDWGRGNEKSPTETVDYS- 640

  Fly   576 GSLGTVLLSAMA--IRSFNWPIVLILGGLVG-------SFYIYEYAAWTTAAQERSFKS------ 625
                 ||..|::  :..:...:..:|...|.       :.:..|:|:..|..|.|..:|
E. coli   641 -----VLQRALSAEVDLYCQQMAKVLAEQVDESVTAGMNTFFAEFASCLTELQTRLRESLALRQQ 700

  Fly   626 --QYARLLQQRLRSDVQQTV 643
              ...||:||:|    ||||
E. coli   701 NESVVRLMQQQL----QQTV 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzo	NP_732840.1	DLP_2	87..334	CDD:206739	58/363 (16%)
		Fzo_mitofusin	566..716	CDD:461432	22/95 (23%)
rdcA	NP_418533.1	PRK09866	1..741	CDD:182123	126/735 (17%)