Protein Alignment fzo and DRP4C

DIOPT Version :10

• Sequence 1: NP_732840.1
• Gene: fzo / 42745
• FlyBaseID: FBgn0011596
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_176252.1
• Gene: DRP4C / 842345
• AraportID: AT1G60500
• Length: 669
• Species: Arabidopsis thaliana
• Alignment Length: 706
• Identity: 131/706 - (18%)
• Similarity: 245/706 - (34%)
• Gaps: 216/706 - (30%)

  Fly     3 ESDSGESTSSVSSFISSSSSSRLSEFVDAKTELQDIYHDLSNYLSNFLTILEETVLLKDRQMLEH 67
            :|.|.:...||.:.|.||.:.|:...:|....|::            |.::.|.:         |
plant    21 KSRSNKDVVSVEAPIISSYNDRIRPLLDTVDRLRN------------LNVMREGI---------H 64

  Fly    68 LCAFSSRVEAIAKVLSRDRMKVAFFGRTSNGKSAVINALLHEKILPSAMGHTT--SCFCQVQANG 130
            |                  ..:...|..|:|||:|:.:|.... ||...|..|  ....::|.:.
plant    65 L------------------PTIVVVGDQSSGKSSVLESLAGIS-LPRGQGICTRVPLVMRLQRSS 110

  Fly   131 SNETE------HVKVEQEDEHM--ELSALSQLASAHSPGALKPSTLLQVNMAKNRCSILDYDVVL 187
            |.|.|      ...|..::||:  .:.|.:.:.:....|.......|.|..|...      |:.:
plant   111 SPEPEIWLEYNDKVVPTDEEHIAEAIRAATDVIAGSGKGVSDAPLTLHVKKAGVP------DLTM 169

  Fly   188 MDTPGV----------DVTAQLDDCLDSYCMDADVFIL-VLNAESTVS-------RVERQFFK-- 232
            :|.||:          ::..|:...:..|....:..|| ||:|  ||.       |:.|:..|
plant   170 VDLPGITRVPVNGQPENIYEQISGMIMEYIEPQESIILNVLSA--TVDFTTCESIRMSRKVDKTG 232

  Fly   233 ----------DVA-----SKLSRPNLFI------LNNR-----WDKASSLE-------------- 257
                      |:|     .|::..::.|      :.||     :::|...|
plant   233 QRTLAVVTKADMAPEGLLQKVTADDVSIVLGYVCVRNRIGEETYEEARMQEELLFRTHPVLSLID 297

  Fly   258 ------PEMEQK---VKDQHMERCVNLLVDELGVYSTAQEAWERIYHVSALEALHIRNGQ----I 309
                  |.:.||   ::...:.||:..:|.::.     |:....:..::.|..:....|:    :
plant   298 EDIVGIPVLAQKLMLIQSSMIARCLPKIVSKIN-----QKLDTAVLELNKLPMVMASTGEALMAL 357

  Fly   310 TNPSGQTQQRYQEFLRFENDFS--------NCLA-VSALKTKFGPHLLSAQKILNQLKSTLICPF 365
            .:..|..::.....| .:.|||        :|.| ::.:.::|...|        |.|...:..|
plant   358 MDIIGSAKESLLRIL-VQGDFSEYPDDQNMHCTARLADMLSQFSDSL--------QAKPKEVAEF 413

  Fly   366 IEKVSRLIDENK--------ERRANLNAEIEDWLILMQEDREALQYCFEELTEMTQRVGRCVLND 422
            :....:::||.|        .|.|        :|.::.:..:.:|   ::..|...::.     |
plant   414 LMDEIKILDECKCVGLPNFIPRSA--------FLAILSQHVDGIQ---DKPVEFINKIW-----D 462

  Fly   423 QIKTLIPSSVLSFSQPFHPEFPAQIGQYQRSLCAHLDKLLEDRVLQCLSIPLQRKILDI------ 481
            .|:.::.|.....|..| |:..:.|.:..|:|   :.|:.|..|.:.:.|....|:.|.
plant   463 YIEDVLSSVTAKRSDNF-PQIQSSIKRAGRNL---ISKIKEQSVNRVMEIVEMEKLTDYTCNPEY 523

  Fly   482 -----------EKEIGLPIA-ENSCDWQLIYGLDCQ--SYMSDFQPDL---RFRFSLGFTALW-- 527
                       |..|...:. ||..|:..:.|....  |::..:...|   .|...:..|:.|
plant   524 MTSWTQKTSAQESFIDAVVKNENIPDYFSVTGFGNVKISHLRKYHAHLLIPAFDMKMRITSYWKI 588

  Fly   528 --HRLEGNLPLHASPFRIQKLQNGHKK----CSPLPPLVNGNHWQMLES--LVKSK 575
              .|:..||.|:.. ..::.|.|...:    ...:.|...|...:|||.  ||.||
plant   589 VLRRIVDNLALYLQ-LSVKSLVNTRFQKEIVAEMVDPRDGGGVEKMLEESPLVASK 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzo	NP_732840.1	DLP_2	87..334	CDD:206739	61/337 (18%)
		Fzo_mitofusin	566..716	CDD:461432	7/12 (58%)
DRP4C	NP_176252.1	DLP_1	63..323	CDD:206738	54/295 (18%)
		Dynamin_M	248..529	CDD:460033	50/314 (16%)
		GED	567..664	CDD:128597	19/78 (24%)