Protein Alignment fzo and dnm2a

DIOPT Version :10

• Sequence 1: NP_732840.1
• Gene: fzo / 42745
• FlyBaseID: FBgn0011596
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: XP_068073278.1
• Gene: dnm2a / 559334
• ZFINID: ZDB-GENE-050913-84
• Length: 903
• Species: Danio rerio
• Alignment Length: 800
• Identity: 154/800 - (19%)
• Similarity: 285/800 - (35%)
• Gaps: 245/800 - (30%)

  Fly    70 AFSSRVEAIAKVLSRDRMKVAFFGRTSNGKSAVINALLHEKILPSAMGHTT--SCFCQVQANGSN 132
            ||||    |.:..:.|..::|..|..|.|||:|:...:....||...|..|  ....|:..|.:.
Zfish    19 AFSS----IGQSCNLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLVNNKAE 79

  Fly   133 ETE--HVK----VEQEDEHMELSALSQLASAHSPGALKPSTLLQVNMAKNRCSILDYDVVLMDTP 191
            ..|  |.|    |:.::...|:.|.:...:..:.| :.|   :.:|:.....::|  ::.|:|.|
Zfish    80 YAEFLHCKGRKFVDFDEVRQEIEAETDRITGSNKG-ISP---IPINLRVYSPNVL--NLTLIDLP 138

  Fly   192 GVDVTAQLDDCLDSYCMDADVFILVLNAESTVSRVERQFFKDVASKLSRPNLFIL---NNRWDKA 253
            |:...|..|...|                     :|.|....:...::|.:..||   ....|.|
Zfish   139 GMTKVAVGDQPPD---------------------IEHQIRDMIMQFITRESCLILAVTPANMDLA 182

  Fly   254 SSLEPEMEQKVKDQHMERCVNLL--VDELGVYSTAQEAWERIYHVSALEALHIRNGQITNPSGQT 316
            :|...::.::|..|.: |.:.::  :|.:...:.|::..|.       :.|.:|.|.|     ..
Zfish   183 NSDALKVAKEVDPQGL-RTIGVITKLDLMDEGTDARDILEN-------KLLPLRRGYI-----GV 234

  Fly   317 QQRYQEFLRFENDFSNCLAVSA-----------LKTKFG-PHLLSA--QKILNQLKSTLICPFIE 367
            ..|.|:.:....|....||...           :..:.| |||..|  |::.|.::.||  |.:.
Zfish   235 VNRSQKDIDGRKDIRAALAAERKFFLSHPSYRHMAERMGTPHLQKALNQQLTNHIRDTL--PGLR 297

  Fly   368 KVSRLIDENKERRANLNAEIEDWLILMQED--REALQYCFEELTEMTQRVG----RCV--LNDQI 424
              |:|    :.:..:|..|:|::.....:|  |:.     :.|.:|.|:.|    :|:  ..||:
Zfish   298 --SKL----QSQLLSLEKEVEEYKNFRPDDPTRKT-----KALLQMVQQFGVDFEKCIEGSGDQV 351

  Fly   425 KTLIPSSVLSFSQPFHPEFPAQI-------GQYQRSLCAHLDK---------------------- 460
            .|...|.....::.||..||.::       .:.:|.: :|..|
Zfish   352 DTAELSGGARINRIFHERFPFELVKIVFDEKELRREI-SHAIKNVHGVRTGLFTPDLAFEAIVKK 415

  Fly   461 ---LLEDRVLQCLSIPLQRKI-----------------LDIEKEIGLPI--AENSCDWQLIYGLD 503
               .|::..|:|:.:.:|..|                 .:.|:.:...:  .|.....|::..:|
Zfish   416 QIIKLKEPCLKCIDLVIQELINTFRQCTNKLSSYPRLREETERIVTTYVREREGKTKDQVLLLID 480

  Fly   504 CQ-SYMSDFQPDLRFRFSLGFTAL-WHRL-EGNLPLHASPFRIQKLQNGHKKCSPLPPLVNGNHW 565
            .: ||::....|.     :||..| ..|| :|.:|.:::....|:  |...|...:|..:.|...
Zfish   481 TELSYINTNHEDF-----IGFANLDLRRLDDGTIPGYSNNSAQQR--NIVNKKRAIPNQLGGLRE 538

  Fly   566 QMLESLVKSKGSLGTVLLSAMAIRSFNWPIVLILGGLVGSFY-------------IYEYAAWTTA 617
            ...|.::: ||.| |:.:|.|...|..:..||....|  |:|             .:......|.
Zfish   539 GEAEKVIR-KGWL-TLNISIMKGGSKEYWFVLTAESL--SWYKDEEINKNVHLTCFFNICKHITE 599

  Fly   618 AQ---------------ERSFKSQ--------------YARLLQQRLRSDVQQTVSGFEL----- 648
            .:               |:.|.|.              |..|.|..|..|.|:.:..::.
Zfish   600 KEKKYMLPLDNLKLRDVEKGFMSTKHIFAIFNTEQRNVYKDLRQIELACDSQEDMDSWKASFLRA 664

  Fly   649 ------------------------QLRQHLATVRNCWEAQ---SNETLNDLNVRTAELTKQIQSM 686
                                    ||.:.:.|:||..::.   .|:|:.||..:|
Zfish   665 GVYPEKDQVESEEAAPADSFSMDPQLERQVETIRNLVDSYIGIVNKTIRDLMPKT---------- 719

  Fly   687 EVLQLSLKKFRD--KGQLLA 704
             ::.|.:...:|  ..:|||
Zfish   720 -IMHLMINSAKDFIHSELLA 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzo	NP_732840.1	DLP_2	87..334	CDD:206739	51/259 (20%)
		Fzo_mitofusin	566..716	CDD:461432	37/214 (17%)
dnm2a	XP_068073278.1	DYNc	6..245	CDD:197491	56/269 (21%)
		Dynamin_M	215..498	CDD:460033	58/313 (19%)
		PH_dynamin	544..670	CDD:269958	22/129 (17%)
		GED	690..780	CDD:460495	13/59 (22%)
		PHA03247	<782..900	CDD:223021