Protein Alignment fzo and dnm1l

DIOPT Version :9

• Sequence 1: NP_732840.1
• Gene: fzo / 42745
• FlyBaseID: FBgn0011596
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: XP_005163105.1
• Gene: dnm1l / 393896
• ZFINID: ZDB-GENE-040426-1556
• Length: 727
• Species: Danio rerio
• Alignment Length: 852
• Identity: 142/852 - (16%)
• Similarity: 281/852 - (32%)
• Gaps: 327/852 - (38%)

  Fly    65 LEHLCAFSSRVEAIAKVLSRDRM---KVAFFGRTSNGKSAVINALLHEKILPSAMG--------- 117
            :|.|....::::.:...:..|.:   ::|..|..|:|||:|:.:|:...:||...|
Zfish     1 MEALIPVINKLQDVFNTVGADIIQLPQIAVVGTQSSGKSSVLESLVGRDLLPRGTGIVTRRPLIL 65

  Fly   118 ----------------------------------------HTT----SCFCQVQANGSNETEHVK 138
                                                    ||.    :.|.:::....||||.|.
Zfish    66 QLVHVDPEDRRKTSEENEPNTWKNGRLYKGVDGEEWGKFLHTKNKIYTDFDEIRQEIENETERVS 130

  Fly   139 -----VEQEDEHMELSALSQLASAHSPGALKPSTLLQVNMAKNRCSILDYDVVLMDTPGV----- 193
                 :..|..|:::         .||..:                    ::.|:|.||:
Zfish   131 GNNKGISDEPIHLKI---------FSPHVV--------------------NLTLVDLPGITKVPV 166

  Fly   194 -----DVTAQLDDCLDSYCMDADVFILVLNAEST------VSRVERQFFKDVASKLSRPNLFILN 247
                 |:..|:.:.:..|..:.:..||.:.|.:|      ..:|.|:...|     .|..|.::.
Zfish   167 GDQPKDIELQIRELILKYISNPNSIILAVTAANTDMATSEALKVAREVDPD-----GRRTLAVVT 226

  Fly   248 NRWDKASSLEPEMEQKVKDQHMERCVNLLVDELGVYSTAQEAWERIYHVSALEALHIRN-----G 307
                |...::...:  ..|..|.|.:.:.:..:||.:.:|              |.|.|     .
Zfish   227 ----KLDLMDAGTD--AMDVLMGRVIPVKLGLIGVVNRSQ--------------LDINNKKSVAD 271

  Fly   308 QITNPSGQTQQRYQEFLRFENDFSNCLAVSALKTKFGPHLLSAQKILNQLKSTLICPFIEKVSRL 372
            .|.:..|..|::|                .:|..:.|...|:  :.||:|       .:..:...
Zfish   272 SIRDEHGFLQKKY----------------PSLANRNGTKYLA--RTLNRL-------LMHHIRDC 311

  Fly   373 IDENKERRANLNAEIEDWL-------------ILMQEDREALQYC--------FEELTEMTQRVG 416
            :.|.|.|...|:|:.:..|             :|....:.|.:||        :.|..|:.....
Zfish   312 LPELKTRINVLSAQYQSLLSSYGEPVEDMSATLLQLITKFATEYCNTIEGTAKYIETAELCGGAR 376

  Fly   417 RCVLNDQI--KTL-------------IPSSVLSFSQP----FHPEFPAQIGQYQRSLCAHLDKLL 462
            .|.:..:.  :||             :.:::.:.:.|    |.||...::      |.....|.|
Zfish   377 ICYIFHETFGRTLESVDPLGGLTTIDVLTAIRNATGPRPALFVPEVSFEL------LVKRQVKRL 435

  Fly   463 EDRVLQCLSI---PLQR-----------------KILDIEKEI-------GLPIAENSCDWQLIY 500
            |:..|:|:.:   .:||                 |:.|...|:       .||:..     ::::
Zfish   436 EEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTSLLRKRLPVTN-----EMVH 495

  Fly   501 GLDC--QSYMSDFQPDLRFRFSLGFTALWHRLEGNL---------PLHASPFRIQKLQN-GHKKC 553
            .|..  .:|::...||  |..:.|.      :..|:         .|..|..|.:.|:. |.:..
Zfish   496 NLVAIELAYINTKHPD--FADACGL------MNNNIEEQRRNRMRELPTSVPRDKSLKGPGGQSM 552

  Fly   554 SPL---------PPLVNG---------NHWQ-MLESLVKSKGSLGTVLLSAM--------AIRSF 591
            ||.         |.:..|         ..|: ||:...:.:|...|.|.|::        |:...
Zfish   553 SPTDQPSAEGDGPKMAGGAQAEQEGGTGTWRGMLKKGDEGQGEEKTKLQSSIPASPQKGHAVNLL 617

  Fly   592 NWPIVLILGGLVGSFYIYEYAAWTTAAQ-------ERSFKSQYARLLQQRLRSDVQQTVSGFELQ 649
            :.|:.:              |...:|.:       ||..|| |..::::.::..|.:.|..|
Zfish   618 DVPVPV--------------ARKLSAREQRDCEVIERLIKS-YFLIVRKNIQDSVPKAVMHF--- 664

  Fly   650 LRQHLATVRNCWEAQ------SNETLNDLNVRTAELTKQIQSMEVLQLSLKKFRDKGQLLASRLG 708
            |..|   |::..:::      ....|:||...:.::.::......:   ||..:...|::|
Zfish   665 LVNH---VKDSLQSELVGQLYKPALLDDLLTESEDMAQRRNEAADM---LKALQKASQVIA---- 719

  Fly   709 DFQETYL 715
            :.:||:|
Zfish   720 EIRETHL 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzo	NP_732840.1	DLP_2	87..334	CDD:206739	53/328 (16%)
		Fzo_mitofusin	572..716	CDD:282633	29/165 (18%)
dnm1l	XP_005163105.1	DLP_1	23..313	CDD:206738	59/368 (16%)
		CrfC	99..720	CDD:223771	125/746 (17%)
		Dynamin_M	238..521	CDD:279383	57/340 (17%)
		GED	633..721	CDD:280391	18/101 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0699
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900