Protein Alignment fzo and eat-3

DIOPT Version :9

• Sequence 1: NP_732840.1
• Gene: fzo / 42745
• FlyBaseID: FBgn0011596
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_495986.3
• Gene: eat-3 / 174476
• WormBaseID: WBGene00001134
• Length: 964
• Species: Caenorhabditis elegans
• Alignment Length: 842
• Identity: 149/842 - (17%)
• Similarity: 286/842 - (33%)
• Gaps: 230/842 - (27%)

  Fly    13 VSSFISSSSSSR-----LSEFVDAKTELQDIYHDL----SNYLSNFLTILEETVLLKDRQMLEHL 68
            ::|.:|:.||.:     ..:.|.|:..:|.:..::    |.|......:.:|..:||.|.:|...
 Worm   186 LASLMSAFSSKKDEPEEKKDNVSAEERIQKLQEEMLKTQSQYQRELERLEKENKVLKQRLLLSDD 250

  Fly    69 CAF-------SSRVEAIAKVL------------SRDRMKVAFFGRTSNGKSAVINALLHEKILPS 114
            .|.       .|.::..::||            |.:..:|...|..|.||::|:..:...:|.|.
 Worm   251 KAAIRLKRLKRSLIDMYSEVLDLLNEYDSSYNTSDNLPRVVVVGDQSAGKTSVLEMVAQARIFPR 315

  Fly   115 AMGHTTSCFCQVQANGSNETEHV-KVEQEDEHMELSALSQLASAHSPGALKPSTLLQVNMAKNRC 178
            ..|...: ...|:...|....|| :........:|:..:.|..      |:..|  :|.|   |.
 Worm   316 GSGEMMT-RAPVKVTLSEGPYHVAQFRDSSREFDLTKETDLQQ------LRNET--EVRM---RN 368

  Fly   179 SILDYD------------------VVLMDTPGVDVTAQLDDCLDSYCMDADVFILVLNAESTVSR 225
            |:.|..                  :||:|.|||..|...|              :....:..:.|
 Worm   369 SVRDGKTVSNEVISLTVKGPNLPRMVLVDLPGVISTVTAD--------------MARETKDDIIR 419

  Fly   226 VERQFFKDVASKLSRPNLFIL-----------NNRWDKASSLEPEMEQKVKDQHMERCVNLLVDE 279
            :.:       :.:..||..||           :|..|..||::|..::.:.   :...|::....
 Worm   420 MSK-------AHMENPNAIILCIQDGSVDAERSNVTDLVSSIDPSGKRTIL---VLTKVDMAEKN 474

  Fly   280 LGVYSTAQEAWE-RIYHVSALEALHIRNGQITNPSGQTQQRYQEFLRFENDF---SNCLAVSALK 340
            |......::..| :::.:.||....:..|:     |.:.....|..::|.:|   |..|....||
 Worm   475 LANPDRIKKILEGKLFPMKALGYFGVVTGR-----GNSSDSIDEIRKYEENFFSTSQLLRDGVLK 534

  Fly   341 TKFGPHLLSAQKILNQLKSTLICPFIEKVSRLIDENKERRANLNAEIED-WLILMQEDREALQ-- 402
                |..::.:.:...:.........:.:....|..:..:.||.||.:: :|.:.|.:|:.|.
 Worm   535 ----PSQMTTRNMSLAVSDCFWRMVRDSIESQTDAFRAAKFNLEAEWKNHFLRIRQLNRDELYDK 595

  Fly   403 ---YCFEELTEMTQRVG----RCVLNDQI----------KTLIPSSVLSFSQPFHPEFPAQIGQY 450
               ...:|:..:: .:|    ..:|.|::          :.|:|:...|.|..|:.....::..:
 Worm   596 ARGEILDEIVNLS-LIGVEEWEKLLQDKLWSGISSHVFDQILMPAYASSSSGSFNTTVDIKLKHF 659

  Fly   451 ------QRSLCAHLDKLLEDRVLQCLSIPLQRK----ILDIEKEIGLPIAENSCDWQLIYGLD-- 503
                  |:|:....|.|.|....|.......:|    :.|..||..:..|      .|.:|.|
 Worm   660 ADKQLAQKSIETGWDTLKEVFFRQINQDARTKKDHDPVFDALKEAVIEEA------MLTHGWDDK 718

  Fly   504 CQSYMSDFQPDLRFRFSLGFTALW-------HR-------------LEGNLPLHASPFRIQK--L 546
            ...|:...|.:.....::.....|       |:             .:...|..||.:.:.|  .
 Worm   719 AMDYLRVIQLNAMEDRAVQDKRSWDAACNFLHKAASERLAAVKKQLTDDRGPGWASKWLMWKTPT 783

  Fly   547 QNGHKKCSPLPPLVNGNHWQMLESLVKSKGSL---------------GTVLLSAMAIRSFNWPIV 596
            .:.|..|     ::....:.:|.:..:.|.:|               |.:.:...:||. .|.:|
 Worm   784 ADNHYSC-----VIQDELYSILGADPEHKQALTDDDITVIRRNIETKGVLEVPTESIRK-QWKLV 842

  Fly   597 L---ILGGLVGSFYIYEYAAWTTAAQERSFKSQYARLLQQRLRS---DVQQTVSGFELQ------ 649
            .   .|..::.|              .:...|.|....|..:..   |.|..|..:.:|
 Worm   843 FKKHFLERIINS--------------SKDCLSMYQMYRQGMIEGQDIDCQTIVLFYRIQKMVNLT 893

  Fly   650 ---LRQHLA-TVRNCWEAQSNETLND-----------LNVRTAELTKQIQSMEVLQLSLKKF 696
               |||.:. |.....|.:..|.|:|           |..|..:|.::||.:..:|..|::|
 Worm   894 CNALRQQITNTEHRRLEKEIKEVLDDWSQEPDIKKKYLTGRRVDLAEEIQQVRRIQEKLEEF 955

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzo	NP_732840.1	DLP_2	87..334	CDD:206739	51/280 (18%)
		Fzo_mitofusin	572..716	CDD:282633	32/167 (19%)
eat-3	NP_495986.3	Smc	<186..>278	CDD:224117	18/91 (20%)
		DLP_1	286..560	CDD:206738	55/318 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0699
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900