Protein Alignment fzo and Dnm1

DIOPT Version :9

• Sequence 1: NP_732840.1
• Gene: fzo / 42745
• FlyBaseID: FBgn0011596
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: XP_006497725.1
• Gene: Dnm1 / 13429
• MGIID: 107384
• Length: 914
• Species: Mus musculus
• Alignment Length: 610
• Identity: 116/610 - (19%)
• Similarity: 205/610 - (33%)
• Gaps: 201/610 - (32%)

  Fly     7 GESTSSVSSFISSSSSSRLSEFVDAKTELQDIYHDLSNYLSNFLTILEETVLLKDRQMLEHLCAF 71
            |.|.......|..|::..:|  ||.|.    :.|.||..|.:.:..|..|:......:.:|
Mouse     2 GFSPERRDEIIQCSAAGEVS--VDPKI----LQHFLSRCLVSSVLSLCSTLGPPAHPLSQH---- 56

  Fly    72 SSRVE-------------AIAKVLSRDRMKVAFFGRTSNGKSAVINALLHEKILPSAMGHTTSCF 123
            ||||.             ::...||. |..::...|...|      |......||...|..|...
Mouse    57 SSRVAGQSICCLWPCLEFSVGAGLSH-RTSLSIPTRHPGG------AKDERDFLPRGSGIVTRRP 114

  Fly   124 CQVQANGSN----ETEHVK----VEQEDEHMELSALSQLASAHSPGALKPSTLLQVNMAKNRCSI 180
            ..:|...|.    |..|.|    .:.|:..:|:.|.:...:..:.| :.|   :.:|:......:
Mouse   115 LVLQLVNSTTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKG-ISP---VPINLRVYSPHV 175

  Fly   181 LDYDVVLMDTPGV----------DVTAQLDDCLDSYCMDADVFILVLNAESTVSRVERQFFKDVA 235
            |  ::.|:|.||:          |:..|:.|.|..:....:..||.::..::
Mouse   176 L--NLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANS------------- 225

  Fly   236 SKLSRPNLFILNNRWDKASSLEPEMEQKVKDQHMERCVNLL--VDELGVYSTAQEAWERIYHVSA 298
                           |.|:|...::.::| |...:|.:.::  :|.:...:.|::..|.
Mouse   226 ---------------DLANSDALKIAKEV-DPQGQRTIGVITKLDLMDEGTDARDVLEN------ 268

  Fly   299 LEALHIRNGQITNPSGQTQQRYQEFLRFENDFSNCLAVSA-----------LKTKFG-PHLLSAQ 351
             :.|.:|.|.|     ....|.|:.:..:.|.:..||...           |..:.| |:|   |
Mouse   269 -KLLPLRRGYI-----GVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYL---Q 324

  Fly   352 KILNQ----------------LKSTLICPFIEKVSRLIDENKERRANLNAEIEDWLILMQEDREA 400
            |:|||                |:|.|:     .:.:.:||.|..|.:..|.....|:.|.:
Mouse   325 KVLNQQLTNHIRDTLPGLRNKLQSQLL-----SIEKEVDEYKNFRPDDPARKTKALLQMVQ---- 380

  Fly   401 LQYC--FEELTEMTQRVGRCVLNDQIKTLIPSSVLSFSQPFHPEFPAQIGQYQRSLCAHLDKLLE 463
             |:.  ||:..|.:        .|||.|...|.....::.||..||.::
Mouse   381 -QFAVDFEKRIEGS--------GDQIDTYELSGGARINRIFHERFPFEL---------------- 420

  Fly   464 DRVLQCLSIPLQRKILDIEKEIGLPIAENSCDWQLIYGLDCQSYMSDFQPDLRFRFSLGFTALWH 528
                    :.::....::.:||...|..       |:|:    ....|.|||.|..::
Mouse   421 --------VKMEFDEKELRREISYAIKN-------IHGI----RTGLFTPDLAFEATV------- 459

  Fly   529 RLEGNLPLHASPFRIQKLQNGHKKC 553
                       ..::|||:....||
Mouse   460 -----------KKQVQKLKEPSIKC 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzo	NP_732840.1	DLP_2	87..334	CDD:206739	45/266 (17%)
		Fzo_mitofusin	572..716	CDD:282633
Dnm1	XP_006497725.1	DLP_1	100..340	CDD:206738	53/289 (18%)
		Dynamin_M	262..548	CDD:366427	58/298 (19%)
		PH_dynamin	566..675	CDD:269958
		GED	702..791	CDD:366984
		PHA03247	<793..910	CDD:223021

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0699
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900