Protein Alignment fzo and Drp1

DIOPT Version :10

• Sequence 1: NP_732840.1
• Gene: fzo / 42745
• FlyBaseID: FBgn0011596
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: XP_061512097.1
• Gene: Drp1 / 1279863
• VectorBaseID: AGAMI1_004795
• Length: 732
• Species: Anopheles gambiae
• Alignment Length: 795
• Identity: 143/795 - (17%)
• Similarity: 270/795 - (33%)
• Gaps: 252/795 - (31%)

  Fly    65 LEHLCAFSSRVEAIAKVLSRDRM---KVAFFGRTSNGKSAVINALLHEKILPSAMGHTT--SCFC 124
            :|.|....::::.:...:..|.:   ::...|..|:|||:||.:|:....||...|..|  ....
Mosquito     1 MEALIPVVNKLQDVFNTVGSDAIQLPQIVVLGSQSSGKSSVIESLVGRTFLPRGTGIVTRRPLVL 65

  Fly   125 QVQANGSNETEH-------VKVEQEDE--HMELSALSQLASAHS---------PGALKPSTLLQV 171
            |:.....::.||       |.||:...  |::....:......|         .||.|......:
Mosquito    66 QLVYTPLDDREHRSAEHGTVAVEEWGRFLHIKNKVFTDFDEIRSEIENETDRMAGANKGICPEPI 130

  Fly   172 NMAKNRCSILDYDVVLMDTPGV----------DVTAQLDDCLDSYCMDADVFILVLNAESTVSRV 226
            |:......::  ::.|:|.||:          |:.||:.|.:..|..:.:..||.:.|.:|
Mosquito   131 NLKIYSTKVV--NLTLVDLPGITKVPVGDQPEDIEAQIKDLVLKYIENPNSIILAVTAANT---- 189

  Fly   227 ERQFFKDVASKLSRPNLFILNNRWDKASSLEPEMEQKV----KDQHMER--------CVNLLVDE 279
                  |:|:          :.....|..::|:..:.:    |...|:.        |..::..:
Mosquito   190 ------DMAT----------SEALKMAKDVDPDGRRTLAVLTKLDLMDAGTDAIDILCGRVIPVK 238

  Fly   280 LGVYSTAQEAWERIYHVSALEALHIRNGQITNPSGQTQQRYQEFLRFENDFSNCLAVSALKTKFG 344
            ||:......:.:.|.....::      .|:.:.:...|::|                ..|.|:.|
Mosquito   239 LGIIGVMNRSQQDIMDKKTID------DQLRDEAAYLQRKY----------------PTLATRNG 281

  Fly   345 -PHLLSAQKILNQLKSTLICPFIEKVSRLIDENKERRANLNAEIEDWLILMQED----------- 397
             |:|   .|.||:|       .:..:...:.:.|.|...:.::.:..|....||
Mosquito   282 TPYL---AKTLNRL-------LMHHIRDCLPDLKTRVNVMASQFQSLLNSYGEDVTDKSQCLLQI 336

  Fly   398 --REALQYCFE--------ELTEMTQRVGRCVLNDQI--KTL-------------IPSSVLSFSQ 437
              :.|..||..        |.||:......|.:..:.  |||             |.:::.:.:.
Mosquito   337 ITKFASAYCSTIEGTSRNIETTELCGGARICYIFHETFGKTLDSIHPLTGLTKMDILTAIRNATG 401

  Fly   438 P----FHPEFPAQIGQYQRSLCAHLDKLLEDRVLQCLSI------------------------PL 474
            |    |.||...::      |.....:.|||..|:|:.:                        .|
Mosquito   402 PRPALFVPEVSFEL------LVKRQIRRLEDPSLRCVELIHEEMQRIIQHCGTEVQQEMLRFPKL 460

  Fly   475 QRKILDIEKEI---GLP----IAENSCDWQLIYGLDCQSYMSDFQPDLRFRFSLGFT---ALW-- 527
            ..||:|:..::   .||    :.||....:|.|   ..:...||..|.....||..|   ..|
Mosquito   461 HEKIVDVVTQLLRRRLPTTNCMVENLVQIELAY---INTKHPDFHKDAALVPSLIKTDSQDQWAI 522

  Fly   528 HRLEGNLP-------------------------LHASPFRIQKLQNGHKKCSP-------LPPLV 560
            |: .||.|                         ......:.|:.|..|....|       |||
Mosquito   523 HQ-TGNPPSRRPGSNRQLALVDKTGMLNLNHDAQQQQQQQQQQQQQNHVSEQPGGWLGSILPP-- 584

  Fly   561 NGNHWQMLESLVKSKGS-LGTVLLS---AMAIRSFNWPIVLILGGLVGSFYIYEYAAWTTAAQ-- 619
                  .:|:::.:.|| .|....|   ...:.|...|:.|:....:.    :.....|...|
Mosquito   585 ------NMEAMIGAPGSESGNSTASNTPTHGVLSPTKPVNLLPDVPMN----HSSRKLTDKEQKD 639

  Fly   620 ----ERSFKSQYARLLQQRLRSDVQQTVSGFEL-----QLRQHLATVRNCWEAQS-NETLND--- 671
                ||..|| |..::::.::..|.:.:..|.:     .|:..|.|  :.:::.| ||.||:
Mosquito   640 CDVIERLIKS-YFYIVRKSIQDSVPKAIMHFLVNFVKDNLQSELVT--HLYKSDSANELLNESDH 701

  Fly   672 LNVRTAELTKQIQSM 686
            :::|..|.:..::::
Mosquito   702 ISIRRKEASDMLKAL 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzo	NP_732840.1	DLP_2	87..334	CDD:206739	50/291 (17%)
		Fzo_mitofusin	566..716	CDD:461432	27/140 (19%)
Drp1	XP_061512097.1	None