Protein Alignment fzo and Opa1

DIOPT Version :10

• Sequence 1: NP_732840.1
• Gene: fzo / 42745
• FlyBaseID: FBgn0011596
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: XP_061511920.1
• Gene: Opa1 / 1270645
• VectorBaseID: AGAMI1_007037
• Length: 997
• Species: Anopheles gambiae
• Alignment Length: 710
• Identity: 125/710 - (17%)
• Similarity: 239/710 - (33%)
• Gaps: 213/710 - (30%)

  Fly    32 KTELQDIY----HDLSNYLSNFLTILEETVLLKDRQMLEHLCAFSSRVEAIAKVLSRDRMKVAFF 92
            |..|.|:|    .:||.|.:::.|             .:||                  .:|...
Mosquito   298 KKSLIDMYSEVLDELSGYDTSYTT-------------ADHL------------------PRVVVV 331

  Fly    93 GRTSNGKSAVINALLHEKILPSAMGHTTSCFCQVQANGSNETEHV-KVEQEDEHMELSALSQLAS 156
            |..|:||::|:.::...:|.|...|...: ...|:...|....|| :....:...:|:..|.||.
Mosquito   332 GDQSSGKTSVLESIAQARIFPRGSGEMMT-RAPVKVTLSEGPYHVAQFRDSEREYDLTKESDLAE 395

  Fly   157 AHSPGALKPSTLLQVNMAKNRCSILDYDV-------------VLMDTPGV----------DVTAQ 198
                  |:....:::..:......:..||             ||:|.||:          |...|
Mosquito   396 ------LRRDVEIRMRNSVRGGKTVSMDVISMTVKGPGLQRMVLVDLPGIISTQTVDMAPDTRDQ 454

  Fly   199 LDDCLDSYCMDADVFILVLNAESTVSRVERQFFKDVASK---LSRPNLFILNNRWDKASSL-EPE 259
            :....:.|..:.:..||.:...|.  ..||....|:.|:   |.:..:|:| .:.|.|..| :|.
Mosquito   455 IKHMTEHYMSNPNAIILCIQDGSV--DAERSNVTDLVSQCDPLGKRTIFVL-TKVDLAEDLADPN 516

  Fly   260 MEQKVKDQHMERCVNLLVDELGVYSTAQEAWERIYHVSALEALHIRNGQ-ITNPSGQTQQRYQE- 322
            ..:|:..                        .:::.:.||....:..|: ..:.|.:|.:.|:|
Mosquito   517 RIRKILS------------------------GKLFPMKALGYFAVVTGRGRKDDSIETIREYEEK 557

  Fly   323 FLRFENDFSNCLAVSALKTKFGPHLLSAQKILNQLKSTLICPFIEKVSRLIDENKERRANLNAEI 387
            |.:....|.:.:.:|...|.....|..|.:....::.|        :.:..|..|..|.||..|
Mosquito   558 FFKNSKLFQSGVTMSHQVTTRNLSLAVADRFWKMVRET--------IEQQADAFKATRFNLETE- 613

  Fly   388 EDWLILMQEDREALQYCFEELTEMTQRVGRCVLNDQIKTLIPSSVLSFSQPFHPEFPAQIGQYQR 452
              |           :..|..|.|.    ||..|.::.|..:...|::.||       ....:::.
Mosquito   614 --W-----------KNNFPRLRES----GRDELFEKAKGEVLDEVVNLSQ-------VSAKKWEE 654

  Fly   453 SLCAHLDKLLEDRVLQCLSIPLQRK--------ILDIE----KEIGLPIAENSCDWQLIYGLDCQ 505
            .:.:.|.:.|...|.:.:.:|..:.        ::||:    .|..||.......|:.:
Mosquito   655 LMNSKLWEKLSSYVFENIYLPAAQSGSQNSFNTMVDIKLRQWAEQALPAKSVEAGWEAL------ 713

  Fly   506 SYMSDFQPDLRFRFSLGFTALWHRLE--GNLPLHASPFRIQKLQNGHKKCSPLPPLVNGNHWQML 568
              ..:||               |.:|  ...|.|...:       .:.|.:.:...:..:.|:
Mosquito   714 --QKEFQ---------------HLMEVARRTPDHDDLY-------DNLKSAVIDEAIRRHSWE-- 752

  Fly   569 ESLVKSKGSLGTVLLSAMAIRSFN----WPIVL----------------ILGGLVGSFYIYEYAA 613
               .|:...|..:.|:.:..||.:    |...:                .:|.:.|.....::..
Mosquito   753 ---DKAIDMLRVIQLNTLEDRSVHDKQEWDQAVRFFEASVKDKLQATETTIGEMFGPSTSQKWLH 814

  Fly   614 WTTAAQERSFKSQYARLLQQRLRSDVQQ--TVSGFEL-QLRQHLAT---------VRNCW 661
            |.::.:|::.:.|....|.:.|.||.:.  |:|..|| .:|::|..         :|..|
Mosquito   815 WRSSTEEQNKRRQVKSELDKILDSDSKHSPTLSYDELTTVRKNLQRGNVEVETDYIRETW 874

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzo	NP_732840.1	DLP_2	87..334	CDD:206739	52/276 (19%)
		Fzo_mitofusin	566..716	CDD:461432	23/128 (18%)
Opa1	XP_061511920.1	None