Protein Alignment fzo and dnm1b

DIOPT Version :9

• Sequence 1: NP_732840.1
• Gene: fzo / 42745
• FlyBaseID: FBgn0011596
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: XP_005165639.1
• Gene: dnm1b / 100333543
• ZFINID: ZDB-GENE-100920-3
• Length: 859
• Species: Danio rerio
• Alignment Length: 854
• Identity: 156/854 - (18%)
• Similarity: 278/854 - (32%)
• Gaps: 328/854 - (38%)

  Fly    53 LEETVLLKDRQMLEHLCAFSSRVEAIAKVLSRDRMKVAFFGRTSNGKSAVINALLHEKILPSAMG 117
            :|:.:.|.:|..    .|||    ||.:..:.|..::|..|..|.|||:|:...:.:..||...|
Zfish     6 MEDLIPLVNRMQ----DAFS----AIGQNANLDLPQIAVVGGQSAGKSSVLENFVGKDFLPRGSG 62

  Fly   118 HTT---------SCFCQ----VQANGSNETEHVKVEQEDEHMELSALSQLASAHSPGALKPSTLL 169
            ..|         :|..:    :...|...|:..:|.||.| .|...::......||        :
Zfish    63 IVTRRPLVLQLINCPTEYAEFLHCKGKKFTDFDEVRQEIE-AETDRITGQNKGISP--------V 118

  Fly   170 QVNMAKNRCSILDYDVVLMDTPGV----------DVTAQLDDCLDSYCMDADVFILVLNAESTVS 224
            .:|:.....::|  ::.|:|.||:          |:.||:.|.|..:....:..:|.::..::
Zfish   119 PINLRVYSPNVL--NLTLVDLPGMTKVPVGDQPADIEAQIRDMLMQFVTKENCLLLAVSPANS-- 179

  Fly   225 RVERQFFKDVASKLSRPNLFILNNRWDKASSLEPEMEQKVKDQHMERCVNLL--VDELGVYSTAQ 287
                                      |.|:|...::.::|..|.| |.:.::  :|.:...:.|:
Zfish   180 --------------------------DLANSDALKIAKEVDPQGM-RTIGVITKLDLMDEGTDAR 217

  Fly   288 EAWERIYHVSALEALHIRNGQITNPSGQTQQRYQEFLRFENDFSNCLAVSA-------------L 339
            |..|.       :.|.:|.|.|     ....|.|:.:..:.|.:  .|:||             |
Zfish   218 EILEN-------KLLPLRRGYI-----GVVNRSQKDIDGKKDIT--AAMSAERKFFLTHPSYRHL 268

  Fly   340 KTKFG-PHLLSA--QKILNQLKSTLICPFIEKVSRLIDENKERRANLNAEIEDWLILMQED--RE 399
            ..:.| |:|..|  |::.|.::.||        ..|.::.:.:..::..|:|::.....:|  |:
Zfish   269 ADRMGTPYLQKALNQQLTNHIRDTL--------PGLRNKLQSQLLSIEKEVEEYKHFRPDDPSRK 325

  Fly   400 ALQYCFEELTEMTQRVG----RCV--LNDQIKTLIPSSVLSFSQPFHPEFPAQIGQYQRSLCAHL 458
            .     :.|.:|.|:..    :|:  ..||:.|:..|.....::.||..||.::
Zfish   326 T-----KALLQMVQQFAVDFEKCIEGSGDQVDTVELSGGARINRIFHERFPFEL----------- 374

  Fly   459 DKLLEDRVLQCLSIPLQRKILDIEKEIGLPIAENSCDWQLIYGLDCQSYMSDFQPDLRFR----- 518
                         :.::....::.|||...|..       |:|:    ....|.||:.|.
Zfish   375 -------------VKMEFDEKELRKEISYAIKN-------IHGI----RTGLFTPDMAFETIVKR 415

  Fly   519 ------------FSLGFTALWHRLEGNLPLHASPFRIQKLQNGHKKCSPLPPL------------ 559
                        ..|..|.|                :..::...||.:..|.|
Zfish   416 QIAKIKEPCQKCVDLVITEL----------------VNTVRQCTKKLAQYPMLREEMERIVTQHI 464

  Fly   560 ---------------------VNGNH--------WQMLESLVKSKGSLGTVLLSAMAIRSFNWPI 595
                                 :|.||        .|...|.:..|.:.|. ....|.||. .|..
Zfish   465 RDRESRTKNQVMLLIDIELAYMNTNHEDFIGFANAQQRSSQMNKKKAAGN-QDEIMVIRK-GWLT 527

  Fly   596 VLILGGLVGSFYIY------EYAAWTTAAQ------------------ERSFKSQ---------- 626
            :..:|.:.|....|      |..:|....:                  |:||.|.
Zfish   528 INNIGIMKGGAKEYWFVMTAENLSWYKDDEEKEKKYMLPLDNLKLRDIEKSFMSSKHVFALFNTE 592

  Fly   627 ----YARLLQQRLRSDVQQTV--------------------------------SGF----ELQLR 651
                |....|..|.||.|:.|                                .||    :.||.
Zfish   593 QRNVYKDYRQLELASDTQEEVDSWKASFLRAGVYPERITDKEKQSDTSDESSSDGFMHSMDPQLE 657

  Fly   652 QHLATVRN---CWEAQSNETLNDLNVRTAELTKQIQSMEVLQLSLKKFRD--KGQLLAS--RLGD 709
            :.:.|:||   .:.|..|:|:.||..:|           ::.|.:...:|  ..:|||:  ..||
Zfish   658 RQVETIRNLVDSYMAIVNKTVRDLMPKT-----------IMHLMINNTKDFIHAELLANLYSCGD 711

  Fly   710 FQETYLTKS 718
             |.|.:.:|
Zfish   712 -QNTLMEES 719

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzo	NP_732840.1	DLP_2	87..334	CDD:206739	51/271 (19%)
		Fzo_mitofusin	572..716	CDD:282633	44/224 (20%)
dnm1b	XP_005165639.1	DYNc	6..245	CDD:197491	59/298 (20%)
		CrfC	78..745	CDD:223771	135/774 (17%)
		Dynamin_M	217..502	CDD:279383	59/362 (16%)
		PH_dynamin	519..629	CDD:269958	20/110 (18%)
		GED	658..746	CDD:280391	19/74 (26%)
		WWbp	<714..837	CDD:304964	2/6 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0699
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900