Protein Alignment cnc and Nfe2l2

DIOPT Version :9

• Sequence 1: NP_001262864.1
• Gene: cnc / 42743
• FlyBaseID: FBgn0262975
• Length: 1430
• Species: Drosophila melanogaster
• Sequence 2: XP_006234458.1
• Gene: Nfe2l2 / 83619
• RGDID: 620360
• Length: 604
• Species: Rattus norvegicus
• Alignment Length: 986
• Identity: 205/986 - (20%)
• Similarity: 325/986 - (32%)
• Gaps: 433/986 - (43%)

  Fly   342 EEESEIAEVLYKQDVDLGFSLDQEAIINASYASGNSAATNVKSKPEDETKSSDPSISESSGFKDT 406
            :::.::.::|::||:|||.|.:               ..:...:.:|.
  Rat    14 QQDMDLIDILWRQDIDLGVSRE---------------VFDFSQRQKDY----------------- 46

  Fly   407 DVNAENEASAASVDDIEKLKAL-----EELQQDKDKNNENQLEDITNEWNGIPFTIDNETGEYIR 466
                          ::||.|.|     |:||::::|....||:            :|.||||::.
  Rat    47 --------------ELEKQKKLEKERQEQLQKEQEKAFFAQLQ------------LDEETGEFLP 85

  Fly   467 L-PLDELLNDVLKLSEFPLQDDLSNDPVASTSQAAAAFNENQAQRIVSETGEDLLSGEGISSKQN 530
            : |...:..|.        ...:|...||...:..|.:.|: ..::::|| ...:....:||...
  Rat    86 IQPAQHIQTDT--------SGSVSYSQVAHIPKQDALYFED-CMQLLAET-FPFVDDHEVSSPTF 140

  Fly   531 RNEAKNKDNDPEKADGDSFSVSD-FEELQNSVGSPLFDLDEDAKKELDEMLQSAVPSYHHPHPHH 594
            ::.|.   :.|...:...|:..| .:.|.:|:.:.:.|| ...:::::::.|...
  Rat   141 QSLAL---DIPSHVESSVFTTPDQAQSLDSSLETAMTDL-SSIQQDMEQVWQELF---------- 191

  Fly   595 GHPHAHPHSHHHASMHHAHAHHAAAAAAAHQRAVQQANYGGGVGVGVGVGVGVGSGTGSAFQRQP 659
                                                                             
  Rat   192 ----------------------------------------------------------------- 191

  Fly   660 AAGGFHHGHHQGRMPRLNRSVSMERLQDFATYFSPIPSMVGGVSDMSPYPHHY---PGYSYQASP 721
                        .:|.| :.::.|..|...|  :.:||....:::|....|.|   |....:.
  Rat   192 ------------SIPEL-QCLNTENKQQAET--TTVPSPEATLTEMDSNYHFYSSIPSLEKEV-- 239

  Fly   722 SNGAPGTPGQHGQYGSGANATLQPPPPPPPPHHAAMLHHPNAALGDICPTGQPHYGHNLGSAVTS 786
                                                         |.|   .||:.|....:.:|
  Rat   240 ---------------------------------------------DSC---SPHFLHGFEDSFSS 256

  Fly   787 SMHLTNSSHEADGAAAAAAAYKVEHDLMYYGNTSSDINQTDGFINSIFTDEDLHLMDMNESFCRM 851
            .:...::|.                      ..|.|.|.|   :|:.|.||..
  Rat   257 ILSTDDASQ----------------------LNSLDSNPT---LNTDFGDEFY------------ 284

  Fly   852 VDNSTSNNSSVLGLPSSGHVSNGSGSSAQLGAGNPHGNQANGASGGVGSMSGSAVGAGATGMTAD 916
                    |:.|..||.|                             |||..|   |..:...::
  Rat   285 --------SAFLAEPSGG-----------------------------GSMPSS---AAISQSLSE 309

  Fly   917 LLASGGAGAQGGADRLDASSDSAVSSMGSERVPSLSDGEWGEGSDSAQDYHQGKYGGPYDFSYNN 981
            ||.       |..:..|.|...|.:...:|.....:|.:.|                   .|.|
  Rat   310 LLG-------GPIEGCDLSLCKAFNQKHTEGTVEFNDSDSG-------------------ISLN- 347

  Fly   982 NSRLSTATRQPPVAQKKHQLYGKRDPHKQTPSALPPTAPPAAATAVQSQSIKYEYDAGYASSGMA 1046
                ::.:|..|....:..:||  ||            ||                 |::.|.|.
  Rat   348 ----TSPSRASPEHSVESSIYG--DP------------PP-----------------GFSDSEME 377

  Fly  1047 SGGISEPGAMGPALSKDYHHHQPYGMGASGSAFSGDYTVRP-SPRTSQDLV----QLNHT--YSL 1104
            ... |.||::           :..|..|..:..||| ||:| ||.......    |..:|  ..:
  Rat   378 ELD-SAPGSV-----------KQNGPKAQPTHSSGD-TVQPLSPAQGHSAAVHESQCENTTKKEV 429

  Fly  1105 PQGSGSLPRPQARDKKPLVATKTASKGASAGNSSSVGGNSSNLEEEHLTRDEKRARSLNIPISVP 1169
            |...|....|..:||                       :||.| |.||||||.||::|:||..|.
  Rat   430 PVSPGHQKVPFTKDK-----------------------HSSRL-EAHLTRDELRAKALHIPFPVE 470

  Fly  1170 DIINLPMDEFNERLSKYDLSENQLSLIRDIRRRGKNKVAAQNCRKRKLDQILTLEDEVNAVVKRK 1234
            .|||||:|:|||.:||...:|.||:|||||||||||||||||||||||:.|:.||
  Rat   471 KIINLPVDDFNEMMSKEQFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELE---------- 525

  Fly  1235 TQLNQDRDHLESERKR--------------ISNKFAMLHRHVFQYLRDPEGNPCSPADYSLQQAA 1285
                ||..||:.||::              :..|.:.|:..||..|||.:|.|.||::|||||..
  Rat   526 ----QDLGHLKDEREKLLREKGENDRNLHLLKRKLSTLYLEVFSMLRDEDGKPYSPSEYSLQQTR 586

  Fly  1286 DGSVYLLPREK 1296
            ||:|:|:|:.|
  Rat   587 DGNVFLVPKSK 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cnc	NP_001262864.1	bZIP_CNC	1192..1259	CDD:269846	35/80 (44%)
		coiled coil	1193..1255	CDD:269846	33/75 (44%)
Nfe2l2	XP_006234458.1	bZIP_NFE2-like	493..560	CDD:269868	35/80 (44%)
		coiled coil	494..556	CDD:269868	33/75 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I6996
eggNOG	1	0.900	-	-		E1_KOG3863
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1095280at2759
OrthoFinder	1	1.000	-	-		FOG0002254
OrthoInspector	1	1.000	-	-		otm45530
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24411
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.880