| Sequence 1: | NP_001262864.1 | Gene: | cnc / 42743 | FlyBaseID: | FBgn0262975 | Length: | 1430 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001129495.1 | Gene: | NFE2 / 4778 | HGNCID: | 7780 | Length: | 373 | Species: | Homo sapiens |
| Alignment Length: | 381 | Identity: | 121/381 - (31%) |
|---|---|---|---|
| Similarity: | 179/381 - (46%) | Gaps: | 60/381 - (15%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 947 RVPSLSDGEWGEGSDSAQDYH-----QGKYGGPYDFSYNNNSRLSTATRQPPVAQKKHQLYGKRD 1006
Fly 1007 PHKQTPSALPPTAPPAAATAVQSQSIKYEYDAGYAS-----SGMASGGISEPGAM-------GPA 1059
Fly 1060 LSKDYHHHQPYGMGASGSAFSGDYT---------VRPSPRTSQ--DLVQLNHTYSLPQGSGSLPR 1113
Fly 1114 PQARDKKPLVATKT-----ASKGASAGNSSSVGGNSSNLEEEHLTRDEKRARSLNIPISVPDIIN 1173
Fly 1174 LPMDEFNERLSKYDLSENQLSLIRDIRRRGKNKVAAQNCRKRKLDQILTLEDEVNAVVKRKTQLN 1238
Fly 1239 QDRDHLESERKRISNKFAMLHRHVFQYLRDPEGNPCSPADYSLQQAADGSVYLLPR 1294 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| cnc | NP_001262864.1 | bZIP_CNC | 1192..1259 | CDD:269846 | 30/66 (45%) |
| coiled coil | 1193..1255 | CDD:269846 | 29/61 (48%) | ||
| NFE2 | NP_001129495.1 | Transactivation domain | 1..206 | 46/212 (22%) | |
| Required for interaction with MAPK8. /evidence=ECO:0000250 | 1..83 | 17/75 (23%) | |||
| PXY motif 1 | 61..65 | 2/3 (67%) | |||
| PXY motif 2 | 79..83 | 1/3 (33%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 127..150 | 5/30 (17%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 205..226 | 4/28 (14%) | |||
| bZIP_NFE2-like | 263..330 | CDD:269868 | 30/66 (45%) | ||
| coiled coil | 264..326 | CDD:269868 | 29/61 (48%) | ||
| Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978 | 268..287 | 18/18 (100%) | |||
| Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978 | 291..298 | 3/6 (50%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 97 | 1.000 | Domainoid score | I7244 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S7370 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1095280at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0002254 | |
| OrthoInspector | 1 | 1.000 | - | - | otm41414 | |
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR24411 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R4312 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 9 | 8.960 | |||||