Protein Alignment Irk1 and kcnj1a.3

DIOPT Version :10

• Sequence 1: NP_001262861.1
• Gene: Irk1 / 42742
• FlyBaseID: FBgn0265042
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_001038641.1
• Gene: kcnj1a.3 / 569137
• ZFINID: ZDB-GENE-050420-256
• Length: 368
• Species: Danio rerio
• Alignment Length: 339
• Identity: 134/339 - (39%)
• Similarity: 206/339 - (60%)
• Gaps: 12/339 - (3%)

  Fly   130 YRQTRFSSRRVRKRVVFKHGECNVVQGNVAKRRR-RYLQDIFTTLVDAQWRWTLLVFAASFVFSW 193
            ::..|...|..:.|:|.|.|.||:...||..|.| .|::|.:||.|:.:||:.:|.|.|||..||
Zfish     9 FKDYRLKQRIRKNRLVTKDGRCNIEFDNVMHRNRFAYVRDFWTTFVETRWRFIILYFVASFTLSW 73

  Fly   194 AFFGFIWWIIAYAHNDLEYTNLKNQSPDLVANITHTVCVTQVSNMMSAFLYSVETQTTIGYGNRY 258
            ..||.||:.:|.::.||.:   :|..||      ||.||..|.:|..||::|:|||.|:.|||.|
Zfish    74 FIFGLIWYWLARSNGDLLW---QNPPPD------HTPCVYSVYDMTYAFIFSLETQNTVIYGNVY 129

  Fly   259 VTEECPEAIFTMCIQCITGVFIQAFMVGIVFAKLSRPKKRAQTLLFSRNAVICHRDGVPCLMFRV 323
            ||::||..:..:.||.|.|:.|..|..|||..|::.|||||:|:.||.:||||.:.|..||..||
Zfish   130 VTDQCPAGVALIIIQTIIGILISIFWCGIVITKITLPKKRAKTITFSESAVICPKKGTLCLQIRV 194

  Fly   324 GDMRKSHIIEAHVRAQIIRKKVTKEGEVLPFYQQELHIGADGGEDRLMFIWPTTIVHKIDRNSPL 388
            .::||:.:|.:.:..:::|..|| .||.:...|..:....|.|:|.|.|:.|.|:.|.||::||.
Zfish   195 ANLRKTLMIGSQIYGKLLRTTVT-GGETVILDQVNIDFMVDAGKDNLFFVCPLTLYHIIDKSSPF 258

  Fly   389 YMLSASDMLKERFEVVVMLEGVIESTGMTTQARSSYLPSEVLWGHRFVNVVSFRKETGEYEVDYT 453
            :.::...:.::.||:||.|:|:.|:|..:.|.|:||:|.|::||:.|:.::| |.|.|.|:||::
Zfish   259 FDMAVDTLHQQDFELVVFLDGMAETTSSSCQVRTSYIPQEIMWGYDFLPIIS-RSEEGRYQVDFS 322

  Fly   454 LFNNTYDVDTPLCS 467
            .|.....|.|..||
Zfish   323 NFAKVVPVPTAHCS 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk1	NP_001262861.1	IRK	145..295	CDD:460023	64/150 (43%)
		IRK_C	302..476	CDD:465439	61/166 (37%)
kcnj1a.3	NP_001038641.1	IRK	24..166	CDD:460023	64/150 (43%)
		IRK_C	173..342	CDD:465439	61/166 (37%)