Protein Alignment Irk1 and kcnj1a.6

DIOPT Version :10

• Sequence 1: NP_001262861.1
• Gene: Irk1 / 42742
• FlyBaseID: FBgn0265042
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_001038640.2
• Gene: kcnj1a.6 / 569052
• ZFINID: ZDB-GENE-050420-272
• Length: 370
• Species: Danio rerio
• Alignment Length: 341
• Identity: 140/341 - (41%)
• Similarity: 213/341 - (62%)
• Gaps: 14/341 - (4%)

  Fly   129 RYRQTRFSSRRVRK-RVVFKHGECNVVQGNVAKRRR-RYLQDIFTTLVDAQWRWTLLVFAASFVF 191
            |::..|. .||:|| |:|.|.|.||:..|||.::.. .|:.|.:||||:.:||:.:|.|.||:..
Zfish     8 RFKDYRL-ERRIRKNRLVTKDGRCNIELGNVMRKNGFTYVLDFWTTLVETRWRFIILYFVASYTL 71

  Fly   192 SWAFFGFIWWIIAYAHNDLEYTNLKNQSPDLVANITHTVCVTQVSNMMSAFLYSVETQTTIGYGN 256
            ||..||.:|:.:|.::.||.:   :|.|.|      ||.||..|:.|..|:|||:|||||||.||
Zfish    72 SWFIFGLLWYWLAKSNGDLLW---QNPSED------HTPCVHNVNGMTYAYLYSLETQTTIGCGN 127

  Fly   257 RYVTEECPEAIFTMCIQCITGVFIQAFMVGIVFAKLSRPKKRAQTLLFSRNAVICHRDGVPCLMF 321
            .|:|::||..:..:.||.:.||.|..|..|||..||:.|||||:|:.||::||||.:.|..||..
Zfish   128 IYITDQCPAGVALIIIQVVIGVLIGIFWCGIVMTKLTLPKKRAKTITFSKSAVICPKKGTLCLQI 192

  Fly   322 RVGDMRKSHIIEAHVRAQIIRKKVTKEGEVLPFYQQELHIGADGGEDRLMFIWPTTIVHKIDRNS 386
            ||.::||:.:|.:.:..:::|..|| |||.:...|..:....|.|:|.|.|:.|.|:.|.||::|
Zfish   193 RVANLRKTLMIGSQIYGKLLRTTVT-EGETVILDQVNIDFMVDAGKDNLFFVSPLTLCHIIDKSS 256

  Fly   387 PLYMLSASDMLKERFEVVVMLEGVIESTGMTTQARSSYLPSEVLWGHRFVNVVSFRKETGEYEVD 451
            |.:.::...:.::.||:||.|:|:.|||..:.|.|:||:|.|::||:.|:.::|..|| |.|.|:
Zfish   257 PFFDMAVDTLHQQDFELVVFLDGMAESTSSSCQVRTSYIPQEIMWGYDFLPIISRSKE-GRYRVE 320

  Fly   452 YTLFNNTYDVDTPLCS 467
            ::.|.....|.|..||
Zfish   321 FSNFAKVVPVPTAHCS 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk1	NP_001262861.1	IRK	145..295	CDD:460023	65/150 (43%)
		IRK_C	302..476	CDD:465439	62/166 (37%)
kcnj1a.6	NP_001038640.2	None