Protein Alignment Irk1 and kcnj1b

DIOPT Version :10

• Sequence 1: NP_001262861.1
• Gene: Irk1 / 42742
• FlyBaseID: FBgn0265042
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_001092204.1
• Gene: kcnj1b / 556608
• ZFINID: ZDB-GENE-070620-9
• Length: 375
• Species: Danio rerio
• Alignment Length: 332
• Identity: 129/332 - (38%)
• Similarity: 202/332 - (60%)
• Gaps: 16/332 - (4%)

  Fly   138 RRVRK-RVVFKHGECNVVQGNVAKRRR-RYLQDIFTTLVDAQWRWTLLVFAASFVFSWAFFGFIW 200
            |::|: |:|.|.|.||:..|....:.. .:|:|.:||.|:..|.:.:|:|||:|..||..||.:|
Zfish    16 RKIRRTRLVTKDGHCNIKFGTTEYQSHFAFLKDFWTTFVEIHWCFVILLFAAAFTGSWFVFGLLW 80

  Fly   201 WIIAYAHNDLEYTNLKNQSPDLVANITHTVCVTQVSNMMSAFLYSVETQTTIGYGNRYVTEECPE 265
            :.:|.::.||..:.             .|.|:..::::.:|||||:|||||||||.|.:|..||.
Zfish    81 YSLAKSNGDLSESQ-------------QTKCIENINSLTTAFLYSLETQTTIGYGGRALTGHCPG 132

  Fly   266 AIFTMCIQCITGVFIQAFMVGIVFAKLSRPKKRAQTLLFSRNAVICHRDGVPCLMFRVGDMRKSH 330
            .:..:.||.:.|..|..||.|::.||:|.||:||:|:.||..|||....|..||..||.::||:.
Zfish   133 TVALLIIQSLMGAIINCFMCGLILAKISLPKRRAKTVAFSETAVIRLWKGNLCLQIRVANLRKTL 197

  Fly   331 IIEAHVRAQIIRKKVTKEGEVLPFYQQELHIGADGGEDRLMFIWPTTIVHKIDRNSPLYMLSASD 395
            :|.:|:..:::|..:|.|||.:...|..:....|.|:|.|.|:.|.||.|.||::||...::|.:
Zfish   198 LIGSHIYGKLLRTTITPEGETIILDQVNVDFSVDAGKDNLFFVCPLTIYHVIDKSSPFADMAADN 262

  Fly   396 MLKERFEVVVMLEGVIESTGMTTQARSSYLPSEVLWGHRFVNVVSFRKETGEYEVDYTLFNNTYD 460
            :..:.||:||.|:|..|||.::.|.|:||||.|:.||:.|:.|:| |.:||:|.:|.:.|:.|..
Zfish   263 LQLQDFELVVFLDGTAESTSLSCQVRTSYLPREIKWGYVFLPVIS-RTKTGKYRIDLSNFSKTQQ 326

  Fly   461 VDTPLCS 467
            .|||.|:
Zfish   327 ADTPHCA 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk1	NP_001262861.1	IRK	145..295	CDD:460023	55/150 (37%)
		IRK_C	302..476	CDD:465439	66/166 (40%)
kcnj1b	NP_001092204.1	IRK	24..162	CDD:460023	55/150 (37%)
		IRK_C	171..338	CDD:465439	66/164 (40%)