Protein Alignment Irk1 and Irk3

DIOPT Version :10

• Sequence 1: NP_001262861.1
• Gene: Irk1 / 42742
• FlyBaseID: FBgn0265042
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: XP_061516592.1
• Gene: Irk3 / 3291594
• VectorBaseID: AGAMI1_006500
• Length: 395
• Species: Anopheles gambiae
• Alignment Length: 371
• Identity: 152/371 - (40%)
• Similarity: 218/371 - (58%)
• Gaps: 20/371 - (5%)

  Fly   143 RVVFKHGECNVVQGNVAKRRRRYLQDIFTTLVDAQWRWTLLVFAASFVFSWAFFGFIWWIIAYAH 207
            |||.|.||.||...|:.:|..|:::|:.||||:.|||:.|.||.||:|.||.||..:|:|::|||
Mosquito    30 RVVNKIGERNVRIYNLPQRSIRFVKDLVTTLVEEQWRYVLFVFVASYVGSWVFFAGLWYILSYAH 94

  Fly   208 NDLEYTNLKNQSP------DLVANITHTVCVTQVSNMMSAFLYSVETQTTIGYGNRYVTEECPEA 266
            .|     |...||      |.|     ..||...:|.:...|:|:|||.:.|||.:..||||||:
Mosquito    95 GD-----LIQDSPTGERLGDGV-----MPCVQGATNFIGFVLFSMETQISTGYGEKVPTEECPES 149

  Fly   267 IFTMCIQCITGVFIQAFMVGIVFAKLSRPKKRAQTLLFSRNAVICHRDGVPCLMFRVGDMRKSHI 331
            ...:.||.|.|:.|...::|:|:|||.||.::...:.|||.||||.|||..|.:||:.|.:..|.
Mosquito   150 FGLLTIQLIVGLLIDGAILGVVYAKLVRPPQKISEMKFSRRAVICQRDGQLCFVFRICDRKWQHA 214

  Fly   332 IEAHVRAQIIRKKVTKEGEVLPFYQQELHIGADGGEDRLMFIWPTTIVHKIDRNSPLYMLSASDM 396
            ||..|.|.::..:.|.|||.:...:..|.:..||   ||:.:||.|..|.|||:||||.:||:|:
Mosquito   215 IETKVTAVLLASRRTAEGEEIEKNESYLKLENDG---RLVLLWPVTACHVIDRDSPLYDVSAADL 276

  Fly   397 LKERFEVVVMLEGVIESTGMTTQARSSYLPSEVLWGHRFVNVVSFRKETGEYEVDYTLFNNTYDV 461
            |:.:.|:|:.:.|...:||...|||:||:|||:.|||||.::|.:......|.......:....|
Mosquito   277 LERKLEIVITITGGTMTTGQINQARTSYVPSEICWGHRFRDIVEYDARKQSYVAVNERMHEIEQV 341

  Fly   462 DTPLCSAKQLDELKSEYSKSAKCVNAPFADRTLSASLFQRIASAAS 507
            |||||||:|||.||....:..| .:.|.:.|..|:.:|:..|::.|
Mosquito   342 DTPLCSARQLDMLKKRLQRDVK-QDRPASARQESSIIFKDNANSDS 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk1	NP_001262861.1	IRK	145..295	CDD:460023	65/155 (42%)
		IRK_C	302..476	CDD:465439	75/173 (43%)
Irk3	XP_061516592.1	None