Protein Alignment Irk1 and Kcnj15

DIOPT Version :10

• Sequence 1: NP_001262861.1
• Gene: Irk1 / 42742
• FlyBaseID: FBgn0265042
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_001034146.1
• Gene: Kcnj15 / 16516
• MGIID: 1310000
• Length: 402
• Species: Mus musculus
• Alignment Length: 363
• Identity: 135/363 - (37%)
• Similarity: 208/363 - (57%)
• Gaps: 18/363 - (4%)

  Fly   141 RKRVVFKHGECNVVQGNVAKRRRRYLQDIFTTLVDAQWRWTLLVFAASFVFSWAFFGFIWWIIAY 205
            |.||:.|.|..||....|......||||::||::|.:||:.|.:|||:||.:|..||.:::.||:
Mouse    53 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVVYYAIAF 117

  Fly   206 AHNDLEYTNLKNQSPDLVANITHTVCVTQVSNMMSAFLYSVETQTTIGYGNRYVTEECPEAIFTM 270
            .|.||:...         :|..||.|:.:|.::..|||:|:|:|||||||.|.:|||||.|||.:
Mouse   118 IHGDLQLGE---------SNSNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLL 173

  Fly   271 CIQCITGVFIQAFMVGIVFAKLSRPKKRAQTLLFSRNAVICHRDGVPCLMFRVGDMRKSHIIEAH 335
            ..|.:....|:.|:.|...||::||||||:|:.||..|||..::|..||:.:|.:||||.:|:..
Mouse   174 VAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVISKQNGKLCLVIQVANMRKSLLIQCQ 238

  Fly   336 VRAQIIRKKVTKEGEVLPFYQQELHIGADGGEDRLMFIWPTTIVHKIDRNSPLYMLSASDMLKER 400
            :..::::..||||||.:...|..:....|...:....|.|.|..|.:|..|||..|:..::.::.
Mouse   239 LSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKE 303

  Fly   401 FEVVVMLEGVIESTGMTTQARSSYLPSEVLWGHRFVNVVSFRKETGEYEVDYTLFNNTYDVD--T 463
            ||:||:|...:|||....|:|:||:|.|:.||..||.|||..| .|:|..|::.|.......  |
Mouse   304 FELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSK-NGKYVADFSQFEQIRKSPDCT 367

  Fly   464 PLCSAKQLDELKSEYSKSAKCVNAPFADRTLSASLFQR 501
            ..|:..:..:|:.:|.:..:      .:|.|.:.|.|:
Mouse   368 FYCADSEKQKLEEQYRQEDQ------RERELRSLLLQQ 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk1	NP_001262861.1	IRK	145..295	CDD:460023	60/149 (40%)
		IRK_C	302..476	CDD:465439	60/175 (34%)
Kcnj15	NP_001034146.1	IRK	57..198	CDD:460023	60/149 (40%)
		IRK_C	205..376	CDD:465439	59/171 (35%)