Protein Alignment Irk1 and kcnj10a

DIOPT Version :10

• Sequence 1: NP_001262861.1
• Gene: Irk1 / 42742
• FlyBaseID: FBgn0265042
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: XP_003198936.1
• Gene: kcnj10a / 100538267
• ZFINID: ZDB-GENE-130726-1
• Length: 425
• Species: Danio rerio
• Alignment Length: 381
• Identity: 139/381 - (36%)
• Similarity: 204/381 - (53%)
• Gaps: 53/381 - (13%)

  Fly    89 GGESSGSGTQLSRKESILGSFHRQIRRSIKAVSESPGPLTRYRQTRFSSRRVRKRVVFKHGECNV 153
            ||.|:|:|                           |..|.|           |:||:.|.|..||
Zfish    36 GGTSTGNG---------------------------PAALRR-----------RRRVLSKDGRSNV 62

  Fly   154 VQGNVAKRRRRYLQDIFTTLVDAQWRWTLLVFAASFVFSWAFFGFIWWIIAYAHNDLEYTNLKNQ 218
            ...:|:.|...||:|::||.:|.|||:.|.:|:|:|..:|..||.:|:::|..|.||    |:..
Zfish    63 RIEHVSGRGTLYLRDLWTTFLDMQWRYKLFLFSATFAGTWFVFGVLWYLVALVHGDL----LEFD 123

  Fly   219 SPDLVANITHTVCVTQVSNMMSAFLYSVETQTTIGYGNRYVTEECPEAIFTMCIQCITGVFIQAF 283
            .|.     .||.||.||..:..|||:|:|:|||||||.|.:|||||.||..:.:|.:..:.::.|
Zfish   124 PPS-----NHTPCVMQVQTLTGAFLFSLESQTTIGYGFRCITEECPLAIILLIVQLVITMVMEIF 183

  Fly   284 MVGIVFAKLSRPKKRAQTLLFSRNAVICHRDGVPCLMFRVGDMRKSHIIEAHVRAQIIRKKVTKE 348
            :.|...||::|||||.:|:.||::||:.:.:|.||||.||.:||||.::...|..::::...|||
Zfish   184 ITGTFLAKVARPKKRGETVKFSQHAVVANHEGRPCLMIRVANMRKSLLLGCQVSGKLLQTSQTKE 248

  Fly   349 GEVLPFYQQELHIGADGGEDRLMFIWPTTIVHKIDRNSPLYMLSA-----SDMLKERFEVVVMLE 408
            ||.:...|:.:....|...|....|.|.|..|.||.||||...:|     :|.....||::|::.
Zfish   249 GETVRLDQRNVAFQVDTSSDSPFLILPLTFYHVIDDNSPLRAWAAKGGGWTDPELADFELLVIMS 313

  Fly   409 GVIESTGMTTQARSSYLPSEVLWGHRFVNVVSFRKETGEYEVDYTLFNNTYDVDTP 464
            ..:|.|..|.|.|:||||.|:|||:.|..|||. ..:|:|..|:..|:......||
Zfish   314 ATVEPTSATCQVRTSYLPDEILWGYEFPPVVSL-SPSGKYVADFAFFDKVAKTKTP 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk1	NP_001262861.1	IRK	145..295	CDD:460023	60/149 (40%)
		IRK_C	302..476	CDD:465439	62/168 (37%)
kcnj10a	XP_003198936.1	IRK	54..195	CDD:460023	60/149 (40%)
		IRK_C	202..368	CDD:465439	60/166 (36%)