Protein Alignment Irk1 and kcnj1

DIOPT Version :10

• Sequence 1: NP_001262861.1
• Gene: Irk1 / 42742
• FlyBaseID: FBgn0265042
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: XP_004916228.1
• Gene: kcnj1 / 100487609
• XenbaseID: XB-GENE-483960
• Length: 372
• Species: Xenopus tropicalis
• Alignment Length: 352
• Identity: 156/352 - (44%)
• Similarity: 227/352 - (64%)
• Gaps: 12/352 - (3%)

  Fly   138 RRVRKRVVFKHGECNVVQGNVAKRRR-RYLQDIFTTLVDAQWRWTLLVFAASFVFSWAFFGFIWW 201
            :|.|.|:|.|.|.||:..|||.::.| .:|.||:||::|.:||:.:.||.::|:.||..||.:|:
 Frog    17 QRRRSRLVSKDGRCNIEFGNVEEQSRVAFLADIWTTILDLKWRYKMTVFISAFLGSWFLFGLLWY 81

  Fly   202 IIAYAHNDLEYTNLKNQSPDLVANITHTVCVTQVSNMMSAFLYSVETQTTIGYGNRYVTEECPEA 266
            .:||.|.||         |:...::.||.||..::.:.|:||:|:|||.|||||.|.|||:|..|
 Frog    82 AVAYLHKDL---------PEFNPSVNHTPCVENINGLTSSFLFSLETQVTIGYGFRCVTEQCATA 137

  Fly   267 IFTMCIQCITGVFIQAFMVGIVFAKLSRPKKRAQTLLFSRNAVICHRDGVPCLMFRVGDMRKSHI 331
            ||.:.:|.|.||.|.:||.|.:.||:|||||||:|:.||:||||..|.|..||:.||.::|||.:
 Frog   138 IFLLVVQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANLRKSLL 202

  Fly   332 IEAHVRAQIIRKKVTKEGEVLPFYQQELHIGADGGEDRLMFIWPTTIVHKIDRNSPLYMLSASDM 396
            |.:|:..::::..||.|||.:...|..:....|.|.:.|.|:.|.||.|.||::||.:.:||..:
 Frog   203 IGSHIYGKLLKTTVTPEGETIILDQVNIEFTVDAGSENLFFVSPLTIYHIIDKDSPFFEMSAETL 267

  Fly   397 LKERFEVVVMLEGVIESTGMTTQARSSYLPSEVLWGHRFVNVVSFRKETGEYEVDYTLFNNTYDV 461
            |:..||:||.|:|.:|||..|.|.|:|::|.|||||:||..:||..|| |:|.||::.|:.|.:|
 Frog   268 LQHDFELVVFLDGTVESTSATCQVRTSFIPDEVLWGYRFAPLVSKTKE-GKYRVDFSNFSKTLEV 331

  Fly   462 DTPLCSAKQLDELKSEYSKSAKCVNAP 488
            :||.| |..|...|....||.|..:.|
 Frog   332 ETPHC-AFCLQNEKDAREKSKKGYDNP 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk1	NP_001262861.1	IRK	145..295	CDD:460023	66/150 (44%)
		IRK_C	302..476	CDD:465439	75/173 (43%)
kcnj1	XP_004916228.1	IRK	24..166	CDD:460023	66/150 (44%)
		IRK_C	173..345	CDD:465439	75/173 (43%)