Protein Alignment Irk1 and kcnj15

DIOPT Version :10

• Sequence 1: NP_001262861.1
• Gene: Irk1 / 42742
• FlyBaseID: FBgn0265042
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: XP_004919636.1
• Gene: kcnj15 / 100486399
• XenbaseID: XB-GENE-5794036
• Length: 377
• Species: Xenopus tropicalis
• Alignment Length: 316
• Identity: 129/316 - (40%)
• Similarity: 190/316 - (60%)
• Gaps: 11/316 - (3%)

  Fly   141 RKRVVFKHGECNVVQGNVAKRRRRYLQDIFTTLVDAQWRWTLLVFAASFVFSWAFFGFIWWIIAY 205
            |.||:.|.|..||....|......||||::||::|.:||:.|.:|||:|..:|.|||.|::::|:
 Frog    34 RPRVISKSGHSNVKIDKVEGVFLLYLQDLWTTVIDMKWRYKLTLFAATFFLTWCFFGVIYFVVAF 98

  Fly   206 AHNDLEYTNLKNQSPDLVANITHTVCVTQVSNMMSAFLYSVETQTTIGYGNRYVTEECPEAIFTM 270
            .|.|:....|.|          ||.||..|.:...|||:|:|:|||||||.|::|||||.|||.:
 Frog    99 IHGDMNIEPLSN----------HTPCVMNVDSFTGAFLFSMESQTTIGYGFRFITEECPLAIFML 153

  Fly   271 CIQCITGVFIQAFMVGIVFAKLSRPKKRAQTLLFSRNAVICHRDGVPCLMFRVGDMRKSHIIEAH 335
            ..|.:....|:.|:.|...||::||||||:|:.||..|||...:|..||:.:|.:||||.:|:..
 Frog   154 VAQLVVTTLIEIFITGTFLAKIARPKKRAETIKFSNKAVITKHNGKLCLVVQVANMRKSLLIQCQ 218

  Fly   336 VRAQIIRKKVTKEGEVLPFYQQELHIGADGGEDRLMFIWPTTIVHKIDRNSPLYMLSASDMLKER 400
            :..:::....|||||.:...|..::...|...:....|.|.|..|.:|.||||..|:|.::..:.
 Frog   219 LYGKLLHSYETKEGEKILLQQVNMNFNVDSSSESPFLILPLTFYHVLDDNSPLKDLTADNIKTKD 283

  Fly   401 FEVVVMLEGVIESTGMTTQARSSYLPSEVLWGHRFVNVVSFRKETGEYEVDYTLFN 456
            ||:||:|...:|||....|:|:||||.|:.||:.||.|||...: |:|..|::.|:
 Frog   284 FELVVLLNATVESTSTVCQSRTSYLPDEIYWGYEFVPVVSLSPQ-GKYVADFSNFD 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk1	NP_001262861.1	IRK	145..295	CDD:460023	61/149 (41%)
		IRK_C	302..476	CDD:465439	58/155 (37%)
kcnj15	XP_004919636.1	IRK	38..178	CDD:460023	61/149 (41%)
		IRK_C	185..343	CDD:465439	58/155 (37%)