Protein Alignment Irk1 and kcnj9

DIOPT Version :10

• Sequence 1: NP_001262861.1
• Gene: Irk1 / 42742
• FlyBaseID: FBgn0265042
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: XP_009297143.1
• Gene: kcnj9 / 100334285
• ZFINID: ZDB-GENE-081104-42
• Length: 503
• Species: Danio rerio
• Alignment Length: 472
• Identity: 194/472 - (41%)
• Similarity: 282/472 - (59%)
• Gaps: 65/472 - (13%)

  Fly   112 QIRRSIKAVSESPGPLTRYRQTRFSSRRVRKRVVFKHGECNVVQGNVAKRRRRYLQDIFTTLVDA 176
            |.|:.|:.|.:..|   |:...|  |:|.|:|.|.|:|.|||..||: :...|||.||||||||.
Zfish    82 QHRKKIQVVGQERG---RFGWAR--SKRKRQRYVEKNGRCNVQHGNM-RETYRYLTDIFTTLVDL 140

  Fly   177 QWRWTLLVFAASFVFSWAFFGFIWWIIAYAHNDLEYTNLKNQSPDLVANITHTVCVTQVSNMMSA 241
            .||.:||||..::..:|.|||.||::|||...||::  |:::|        .|.||..|:..:||
Zfish   141 NWRCSLLVFVMAYAVTWLFFGAIWYLIAYCRGDLDH--LEDES--------WTPCVNNVNGFISA 195

  Fly   242 FLYSVETQTTIGYGNRYVTEECPEAIFTMCIQCITGVFIQAFMVGIVFAKLSRPKKRAQTLLFSR 306
            ||:|:||:||||||.|.:|::||.....:.:|.|.|..:.|||||.:|.|:|:|.|||:||:|||
Zfish   196 FLFSIETETTIGYGYRVITDQCPVGTMLLLLQAILGSMVNAFMVGCMFVKISQPNKRAETLVFSR 260

  Fly   307 NAVICHRDGVPCLMFRVGDMRKSHIIEAHVRAQIIRKKVTKEGEVLPFYQQELHIGADGGEDRLM 371
            ||||..||...||||||||:|.|||:.|::||::|:.|.|:|||.:|..|.::.:|.:.|:|||.
Zfish   261 NAVISLRDDKLCLMFRVGDLRSSHIVGANMRAKLIKSKQTQEGEFIPLDQTDISVGFETGDDRLF 325

  Fly   372 FIWPTTIVHKIDRNSPLYMLSASDMLKERFEVVVMLEGVIESTGMTTQARSSYLPSEVLWGHRFV 436
            .:.|..|.|:||..||.:.:|.:.:.||.||:||:|||::|:||||.|||||||..||:|||||.
Zfish   326 LVSPLVISHEIDVRSPFWDMSQNQLEKEDFEIVVILEGMVEATGMTCQARSSYLAEEVMWGHRFS 390

  Fly   437 NVVSFRKETGEYEVDYTLFNNTYDVDTPLCSAKQLDELKSEYSKSAKCVNAPFADRTLSASLFQR 501
            .::...:  |.::|||..|::|::||||.|||::|                ..|...|.|.|:..
Zfish   391 PMMCLAE--GFFDVDYGAFHHTFEVDTPSCSAREL----------------ALAAARLDAHLYWS 437

  Fly   502 IASAASVD-----HLDPASDESLDSGRLQIRSHSIPNGVLASELEPLNNNKHGASFTMGGLTITT 561
            |:|....:     :|...:.:|.||..::                    .:.|.:||:||:|.|
Zfish   438 ISSRLDEEKWEGPNLTEQTGKSTDSESVR--------------------EEQGPTFTVGGVTNT- 481

  Fly   562 TAPSIPNLSSINEKTNS 578
                 .:.|.:.|:..|
Zfish   482 -----QDQSVVGEQNGS 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk1	NP_001262861.1	IRK	145..295	CDD:460023	70/149 (47%)
		IRK_C	302..476	CDD:465439	88/173 (51%)
kcnj9	XP_009297143.1	IRK	110..249	CDD:460023	70/149 (47%)
		IRK_C	256..419	CDD:465439	84/164 (51%)