Protein Alignment Irk1 and kcnj22 ( provisional)

DIOPT Version :10

• Sequence 1: NP_001262861.1
• Gene: Irk1 / 42742
• FlyBaseID: FBgn0265042
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: XP_031760630.1
• Gene: kcnj22 ( provisional) / 100125201
• XenbaseID: XB-GENE-5906252
• Length: 419
• Species: Xenopus tropicalis
• Alignment Length: 336
• Identity: 174/336 - (51%)
• Similarity: 237/336 - (70%)
• Gaps: 13/336 - (3%)

  Fly   138 RRVRKRVVFKHGECNVVQGNVAKRRRRYLQDIFTTLVDAQWRWTLLVFAASFVFSWAFFGFIWWI 202
            :|.|:|.|.|.|:|||..||| :...||..||||||||.:||:.||||...:..:|.|||||||:
 Frog    47 KRRRQRYVEKDGKCNVHHGNV-RETYRYFTDIFTTLVDLKWRFNLLVFTMVYTITWIFFGFIWWL 110

  Fly   203 IAYAHNDLEYTNLKNQSPDLVANITHTVCVTQVSNMMSAFLYSVETQTTIGYGNRYVTEECPEAI 267
            |||...||::          :.:.:.|.||.:::..:||||:|:||:||||||.|.:|::|||.|
 Frog   111 IAYIRGDLDH----------IEDSSWTPCVDKLNGFVSAFLFSIETETTIGYGYRVITDKCPEGI 165

  Fly   268 FTMCIQCITGVFIQAFMVGIVFAKLSRPKKRAQTLLFSRNAVICHRDGVPCLMFRVGDMRKSHII 332
            ..:.:|.|.|..:.|||||.:|.|:|:|||||:||:||..|||..|||..||||||||:|.|||:
 Frog   166 VLLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNQAVISVRDGKLCLMFRVGDLRNSHIV 230

  Fly   333 EAHVRAQIIRKKVTKEGEVLPFYQQELHIGADGGEDRLMFIWPTTIVHKIDRNSPLYMLSASDML 397
            ||.:||::|:.|.|||||.:|..|.::::|.|.|:|||..:.|..|.|:.:..||.:.:|...:.
 Frog   231 EASIRAKLIKSKQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIICHEFNEQSPFWEISKDQLE 295

  Fly   398 KERFEVVVMLEGVIESTGMTTQARSSYLPSEVLWGHRFVNVVSFRKETGEYEVDYTLFNNTYDVD 462
            ||.||:||:|||::|:||||.||||||:.:||||||||:.|::.  |.|.|||||..|:|||:..
 Frog   296 KEEFEIVVILEGMVEATGMTCQARSSYVENEVLWGHRFMPVLTL--EEGFYEVDYDTFHNTYETP 358

  Fly   463 TPLCSAKQLDE 473
            ||.||||:|.|
 Frog   359 TPSCSAKELAE 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk1	NP_001262861.1	IRK	145..295	CDD:460023	71/149 (48%)
		IRK_C	302..476	CDD:465439	94/172 (55%)
kcnj22 ( provisional)	XP_031760630.1	IRK	54..193	CDD:460023	71/149 (48%)
		IRK_C	200..369	CDD:465439	93/170 (55%)