DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment unk and OXS2

DIOPT Version :9

Sequence 1:	NP_001303430.1	Gene:	unk / 42738	FlyBaseID:	FBgn0004395	Length:	673	Species:	Drosophila melanogaster
Sequence 2:	NP_565962.1	Gene:	OXS2 / 818790	AraportID:	AT2G41900	Length:	716	Species:	Arabidopsis thaliana

Alignment Length:	562	Identity:	116/562 - (20%)
Similarity:	184/562 - (32%)	Gaps:	206/562 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 DSTNALNALDKERNLMNEDPKWQDTNYVLANYKTEPCKRPPRLCRQGYA-----CPQYHNSKD-K 222
            |..|::.|.|:.|               :.::|..||.|       .|:     ||..|..:: :
plant   251 DIKNSIYATDEFR---------------MYSFKVRPCSR-------AYSHDWTECPFVHPGENAR 293

  Fly   223 RRSPRKYKYRSTPCPNVKHGEEWGEPGNCEAGDNCQYCHTRTEQQFHPEIYKSTKCNDVQQAGYC 287
            ||.|||:.|...|||:.:.|.       |..||.|:|.|...|...||..|::..|.|   ...|
plant   294 RRDPRKFHYSCVPCPDFRKGA-------CRRGDMCEYAHGVFECWLHPAQYRTRLCKD---GTGC 348

  Fly   288 PRSVFCAFAHVEPCSIDEKTRDHTVYLNELISNAYPDLKAQDAFQRVDNLLNIDGNSTNKMLVDA 352
            .|.| |.|||..               .||
plant   349 ARRV-CFFAHTP---------------EEL----------------------------------- 362

  Fly   353 LENTTNFSKFLSFSRPLDSRSACSMDDPRENSLSASLANTSLLTRSSAPINIPNTTLSNSINDFN 417
                          |||.:.:..::..||.|:..|  |..|||..|.:.:::.:....::..:..
plant   363 --------------RPLYASTGSAVPSPRSNADYA--AALSLLPGSPSGVSVMSPLSPSAAGNGM 411

  Fly   418 SGSF---------AVNIPSSSLTYS-----------PTNHANLFNVDAFNYGGSNKLSNSLSAT- 461
            |.|.         |:::|.|:|..|           ||:..|:. .|.......|:.||:||.:
plant   412 SHSNMAWPQPNVPALHLPGSNLQSSRLRSSLNARDIPTDEFNML-ADYEQQQLLNEYSNALSRSG 475

  Fly   462 -------QNDSSLFFPSRIISPGFGDGLSISPSVRISELNTIRDDINSSSVGNSLFENTLNTAK- 518
                   .|...||......||.|.|                      |::.:::|..|..:|.
plant   476 RMKSMPPSNLEDLFSAEGSSSPRFTD----------------------SALASAVFSPTHKSAVF 518

  Fly   519 NAFSLQSLQSQNNSDLGRITNELLTKNAQIHKL---NGR---------FEDMACKLK-IAELHRD 570
            |.|  |..|.|..|.|..|.....:..:..|.|   .||         ...|:.::. :|:.
plant   519 NQF--QQQQQQQQSMLSPINTSFSSPKSVDHSLFSGGGRMSPRNVVEPISPMSARVSMLAQC--- 578

  Fly   571 KAKQEAQEWKERYDLAQIQLNLPAELR-----------------------------DLSIQKLKQ 606
             .||:.|:.:::....|.:.....|||                             .:|.:.|.:
plant   579 -VKQQQQQQQQQQQQHQFRSLSSRELRTNSSPIVGSPVNNNTWSSKWGSSNGQPDWGMSSEALGK 642

  Fly   607 LQSKLRTDLEEVDKVLYLENAKKCMKCEENNRTVTLEPCNHL 648
            |:|....|.:|.| |.::::..|....|...:..|.....|:
plant   643 LRSSSSFDGDEPD-VSWVQSLVKETPAEAKEKAATSSSGEHV 683

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unk	NP_001303430.1	zf-CCCH	273..299	CDD:279036	10/25 (40%)
		FhaB	<311..548	CDD:225751	49/265 (18%)
		zf-C3HC4_3	626..671	CDD:290631	4/23 (17%)
OXS2	NP_565962.1	ANK	48..182	CDD:238125
		Ank_2	49..159	CDD:289560
		ANK repeat	74..123	CDD:293786
		ANK repeat	125..159	CDD:293786
		ZnF_C3H1	302..326	CDD:214632	10/30 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1595
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2630
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14493
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1211
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910