Protein Alignment unk and unkl

DIOPT Version :10

• Sequence 1: NP_001303430.1
• Gene: unk / 42738
• FlyBaseID: FBgn0004395
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_005164288.1
• Gene: unkl / 565405
• ZFINID: ZDB-GENE-131120-196
• Length: 818
• Species: Danio rerio
• Alignment Length: 868
• Identity: 331/868 - (38%)
• Similarity: 438/868 - (50%)
• Gaps: 275/868 - (31%)

  Fly    12 SSQQEKPNHYTYLKEFRVEQCQSFLQHKCNQHRPFVCFNWHFQNQRRRRPVRKRDGTFNYSADNY 76
            |.|.|||.|||||||||.|||..||||||.|||||.||:|||.|||||||:|:||||||||.|.|
Zfish    12 SPQTEKPTHYTYLKEFRTEQCPLFLQHKCTQHRPFTCFHWHFLNQRRRRPIRRRDGTFNYSPDVY 76

  Fly    77 CTKYDETTGICPEGDECPYLHRTAGDTERRYHLRYYKTCMCVHDTDSRGYCVKNGLHCAFAHGMQ 141
            ||||||||||||:||:|||||||.|||||:||||||||..|:|:||:||:|||||||||||||..
Zfish    77 CTKYDETTGICPDGDDCPYLHRTTGDTERKYHLRYYKTGTCIHETDARGHCVKNGLHCAFAHGPH 141

  Fly   142 DQRPPVYDIKEL---ETLQNAESTLDSTNALNALDK---------ERNLMNEDPKWQDTNYVLAN 194
            |.|||||||:|:   |.|||.:  |.|...:..|..         |:.| ||||:|||||:||||
Zfish   142 DLRPPVYDIREIQAQEALQNGQ--LGSGEGIPDLQPGVLASQAMIEKTL-NEDPRWQDTNFVLAN 203

  Fly   195 YKTEPCKRPPRLCRQGYACPQYHNSKDKRRSPRKYKYRSTPCPNVKHGEEWGEPGNCEAGDNCQY 259
            |||:.|.:||||||||||||.||||:|:||:|||:||||||||:||||:|||||..||:||:|||
Zfish   204 YKTDQCTKPPRLCRQGYACPHYHNSRDRRRNPRKFKYRSTPCPSVKHGDEWGEPSKCESGDSCQY 268

  Fly   260 CHTRTEQQFHPEIYKSTKCNDVQQAGYCPRSVFCAFAHVEPCSIDEKTRDHTVYLNELIS----- 319
            ||:||||||||||||||||||::|.|||||..||||||||.....|:|      ::.|:|
Zfish   269 CHSRTEQQFHPEIYKSTKCNDMRQTGYCPRGPFCAFAHVERIPSTEET------MSTLLSAMQSG 327

  Fly   320 ------NAYPDLKAQDAFQRVDNLLNIDGNS---------------------------------- 344
                  :.||:....:.....:::.:...|:
Zfish   328 SQSKLGSQYPECPVSEWSNNTNSITSSASNNGQSGNVSCSNSPTVTPSSGSNSSLSPIGPIGRPK 392

  Fly   345 --TNKMLVDALENTT--------NFSKFLSFSRPLDSRSACS---------MDDPRE-------- 382
              ||..|..  |:||        |:.|...|.|...:::..|         ||..::
Zfish   393 CFTNGSLCS--ESTTSSVSSPTSNYPKAPGFEREDQAKNLKSQSGENNQKLMDQDKQAHGSVFSV 455

  Fly   383 ---------NSLSASLANTSLLTRSSAPINIPNTTLSN-------------------------SI 413
                     :|:::||| :|:.:.||:|     ||||.                         :.
Zfish   456 VNPLASSITSSITSSLA-SSIGSDSSSP-----TTLSTMNAKATPFYPGSNTVESVIGSALDLNF 514

  Fly   414 NDFN------------------------SGSFAVNIP-----------SSSLTYSPTNHANLFNV 443
            :|.|                        .||..||||           ||||:.||.:..
Zfish   515 SDINVASLDKELEDQDNNGLALTSQRLLGGSAPVNIPGSLARSSSLHSSSSLSASPLSSL----- 574

  Fly   444 DAFNYGGSNKLSNSL--------------------------SATQNDSSLFFPSRIISPGFGDGL 482
                   |..||.||                          ::|||...|        .|...|:
Zfish   575 -------SQSLSQSLLSGMASQQSQTQPPPVKTEHGLLGTPTSTQNSLGL--------NGGAGGI 624

  Fly   483 ------SISPSVRISELNTIRDDINSSSVGNSLFENTLNTAKNAFSLQSLQSQNNSDLGRITNEL 541
                  |.|||              .|.|.:||..||:.:             :::|:||:..||
Zfish   625 WDFMSGSFSPS--------------PSPVFSSLTSNTVGS-------------SSADIGRLLREL 662

  Fly   542 LTKNAQI---------------------HKLNGRFEDMACKLKIAELHRDKAKQEAQEWKERYDL 585
            .....:|                     |:...:.:....:.::||..|:.|:::.:|.:..:|.
Zfish   663 DEAKRKIKQWEEAWHQVKQACEAWQKDAHEAKEQAKSAEAERQLAEQKREDAERKLKELQGDFDA 727

  Fly   586 AQIQLNLP-----AELRDLSIQKLKQLQSKLRTDLEEVDKVLYLENAKKCMKCEENNRTVTLEPC 645
            .....|.|     .||..|.:.||:.:||:||:||:.::.|:|...:|||:.|::::|::.|:||
Zfish   728 LCRSPNTPLLRSYGELEQLPLPKLRSIQSQLRSDLDLIEGVIYQLQSKKCIVCQKHDRSIVLQPC 792

  Fly   646 NHLSICNTCAESVTECPYCQVPV 668
            .|..:|..||....|||||:..:
Zfish   793 QHYVLCQNCASGKKECPYCKTKI 815

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unk	NP_001303430.1	zf_CCCH_5	21..56	CDD:375810	27/34 (79%)
		zf-CCCH	273..299	CDD:459885	20/25 (80%)
		COG4372	484..>621	CDD:443500	35/162 (22%)
		RING-HC_UNK-like	628..665	CDD:438276	16/36 (44%)
unkl	XP_005164288.1	zf_CCCH_5	21..56	CDD:375810	27/34 (79%)
		zf-CCCH	282..308	CDD:459885	20/25 (80%)
		COG4913	<649..>728	CDD:443941	13/91 (14%)
		RING-HC_UNKL	775..818	CDD:438428	17/41 (41%)