back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment unk and Unk

DIOPT Version :9

Sequence 1:	NP_001303430.1	Gene:	unk / 42738	FlyBaseID:	FBgn0004395	Length:	673	Species:	Drosophila melanogaster
Sequence 2:	NP_766157.1	Gene:	Unk / 217331	MGIID:	2442456	Length:	810	Species:	Mus musculus

Alignment Length:	817	Identity:	326/817 - (39%)
Similarity:	426/817 - (52%)	Gaps:	199/817 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLSSQQEKPNHYTYLKEFRVEQCQSFLQHKCNQHRPFVCFNWHFQNQRRRRPVRKRDGTFNYSAD 74
            :|.:|.|||.|||||||||.|||..|:||||.||||:.||:|||.||||||.:|:||||||||.|
Mouse    23 VLQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPD 87

  Fly    75 NYCTKYDETTGICPEGDECPYLHRTAGDTERRYHLRYYKTCMCVHDTDSRGYCVKNGLHCAFAHG 139
            .|||||||.||:||||||||:||||.||||||||||||||.:|:|:|||:|.|.|||||||||||
Mouse    88 VYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHG 152

  Fly   140 MQDQRPPVYDIKEL---ETLQNAESTLD------STNALNALDKERNLMNEDPKWQDTNYVLANY 195
            ..|.|.|||||:||   |.|||.::|::      |..|.:....|: :::|:|:||:|.|||.||
Mouse   153 PHDLRSPVYDIRELQAMEALQNGQTTVEGSIEGQSAGAASHAMIEK-ILSEEPRWQETAYVLGNY 216

  Fly   196 KTEPCKRPPRLCRQGYACPQYHNSKDKRRSPRKYKYRSTPCPNVKHGEEWGEPGNCEAGDNCQYC 260
            ||||||:||||||||||||.||||||:||||||:||||:||||||||:|||:||.||.||.||||
Mouse   217 KTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDACQYC 281

  Fly   261 HTRTEQQFHPEIYKSTKCNDVQQAGYCPRSVFCAFAHVEPCSIDEKTRDHT-----------VYL 314
            ||||||||||||||||||||:||||.|||..||||||:||..:.:..:..:           :|:
Mouse   282 HTRTEQQFHPEIYKSTKCNDMQQAGSCPRGPFCAFAHIEPPPLSDDVQPSSAVSSPTQPGPVLYM 346

  Fly   315 NELISNAYPDLKAQDAFQRVDNLLNIDGNSTNKMLVDAL---ENTTNFSKFLSFSRPLDSRSACS 376
            .....::.|                :..:|.:...:.||   .:.......|..|.|..||.|.:
Mouse   347 PSAAGDSVP----------------VSPSSPHAPDLSALLCRNSGLGSPSHLCSSPPGPSRKASN 395

  Fly   377 MDD---PRENSLS---------------------------ASLANTSLLTRSS------------ 399
            ::.   |.|:||:                           |.|...||..||.
Mouse   396 LEGLVFPGESSLAPGSYKKAPGFEREDQVGAEYLKNFKCQAKLKPHSLEPRSQEQPLLQPKQDVL 460

  Fly   400 --APINIPNTTLSNSINDFNSGSFAVNIPS------------SSLTYSPTN-------HANLFNV 443
              .|:..|   |::||:...:.|.|...||            ::|.:.||:       .:.|.::
Mouse   461 GILPVGSP---LTSSISSSITSSLAATPPSPAGTNSTPGMNANALPFYPTSDTVESVIESALDDL 522

  Fly   444 DAFNYGGSNKLSNSLSATQNDSSLFFPSRI--------------ISPGFGDGLSI-----SPSVR 489
            |...:|.:     :|..|.::|::..||.:              |....|...|.     ||.|.
Mouse   523 DLNEFGVA-----ALEKTFDNSAVPHPSSVTIGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVS 582

  Fly   490 IS-------------ELNTIRDDINSSSVGNSLFENTLNT------AKNAFSLQS----LQSQNN 531
            :|             ..||.   :.:|:...||..|.:|:      |..:||..:    |.....
Mouse   583 LSSHFLQQPQGHLSQSENTF---LGTSASHGSLGLNGMNSSIWEHFASGSFSPGTSPAFLSGPGA 644

  Fly   532 SDLGRITNELLTKNAQIHKLNGRFEDMACKLKIAELHRDKAKQEAQEWKERYDLAQIQLNLPAEL 596
            ::|.|:..||       .:.||..:......|.|:...|..|:||:|..||...|..:..|..|.
Mouse   645 AELARLRQEL-------DEANGTIKQWEESWKQAKQACDAWKKEAEEAGERASAAGAECELAREQ 702

  Fly   597 RD---------------------------------LSIQKLKQLQSKLRTDLEEVDKVLYLENAK 628
            ||                                 ||:..|..:|.:||..||:|||.::...:.
Mouse   703 RDALELRVKKLQEELERLHTVPEAQTLPAAPDLEALSLSTLYSIQKQLRVHLEQVDKAVFHMQSV 767

  Fly   629 KCMKCEENNRTVTLEPCNHLSICNTCAESVTECPYCQ 665
            ||:||:|..|.|.  ||.|..:|..|||. :|||.||
Mouse   768 KCLKCQEQTRAVL--PCQHAVLCELCAEG-SECPVCQ 801

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.