Protein Alignment unk and unk-1

DIOPT Version :9

• Sequence 1: NP_001303430.1
• Gene: unk / 42738
• FlyBaseID: FBgn0004395
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_001263959.1
• Gene: unk-1 / 181059
• WormBaseID: WBGene00016407
• Length: 706
• Species: Caenorhabditis elegans
• Alignment Length: 642
• Identity: 260/642 - (40%)
• Similarity: 346/642 - (53%)
• Gaps: 120/642 - (18%)

  Fly    15 QEKPNHYTYLKEFRVEQCQSFLQHKCNQHRPFVCFNWHFQNQRRRRPVRKRDGTFNYSADNYCTK 79
            ||||:|..||.|||||.|..|.||:|.|||||.||.|||.||||||||::.||:||||.|.||.|
 Worm    63 QEKPSHQHYLNEFRVEACPLFKQHQCQQHRPFTCFKWHFANQRRRRPVKRSDGSFNYSPDIYCDK 127

  Fly    80 YDETTGICPEGDECPYLHRTAGDTERRYHLRYYKTCMCVHDTDSRGYCVKNGLHCAFAHGMQDQR 144
            |||.|||||:|::|.:|||.:||.||:||||||||..|||.||:||.|||||.||||||...|.|
 Worm   128 YDENTGICPDGEDCIFLHRVSGDVERKYHLRYYKTAQCVHPTDARGQCVKNGAHCAFAHTANDIR 192

  Fly   145 PPVYDIKEL--ETLQNAESTLDSTNALNALDKERNLMNEDPKW----QDTNYVLANYKTEPCKRP 203
            ||::|..|:  .|:.:.|.. |.|          :.:.|||:|    ||  :||:.||||.|::|
 Worm   193 PPMFDQHEVGFSTVVDGEGR-DKT----------SFVIEDPQWHFAAQD--HVLSCYKTEQCRKP 244

  Fly   204 PRLCRQGYACPQYHNSKDKRRSPRKYKYRSTPCPNVKHGEEWGEPGNCEAGDNCQYCHTRTEQQF 268
            .||||||||||.||||||:||.|..|||||||||..|..:||.:|..||||||||||||||||||
 Worm   245 ARLCRQGYACPFYHNSKDRRRPPALYKYRSTPCPAAKTIDEWLDPDICEAGDNCQYCHTRTEQQF 309

  Fly   269 HPEIYKSTKCNDVQQAGYCPRSVFCAFAHVEPCSIDEKTRDHTVYLNELISNAYPDLKAQ----- 328
            ||||||||||||:.:.|||||:|||||||     .|.:...|.   |..:.:..|..|.|
 Worm   310 HPEIYKSTKCNDMLEHGYCPRAVFCAFAH-----HDSELHAHR---NPYVGSTQPSPKEQCSPSP 366

  Fly   329 DAF----QRVDNLLNIDGNSTNKMLVDAL-------ENTTNFSKFL-------------SFSRPL 369
            :.|    :|.::.:|....|.:.:|.:.:       ..|.:.|...             ||..|.
 Worm   367 NGFSIPTERFESPINGFSPSYSSVLKNRIPIAKQGYATTDSISSSYPKAPGYERSPIVGSFEMPP 431

  Fly   370 DSRSACSMDDPRENSLSASLANTSLLTRSSAPINIPNTTLSNSINDFNSGSFAVNIPSSSLTYSP 434
            ..|.     |.|..:.|.::.:..:|.|:         .:.|.:...:||:.|:. .:|||..|.
 Worm   432 IGRG-----DQRLRTHSLNMGHLDMLKRN---------MIINGMTSIDSGNPALT-STSSLCRSD 481

  Fly   435 TNHANLFNVDAFNYGGSNKLSNSLSATQNDSSLFFPSRIISPGFGDGLSISPSVRISEL----NT 495
            :.    |||.|         .||| .|.::.||..| ||...  |..|::...||.:.|    ||
 Worm   482 SG----FNVVA---------DNSL-PTLDELSLDLP-RIDES--GTQLNLFNEVRTASLDPYGNT 529

  Fly   496 I-----RDDINSSSVGNSLFENTLNTAKNAFSLQSLQSQNNSDLGRITNELLTKNAQIHKLNGRF 555
            .     :|.:::...|||...|        ||....|...|..:.:..||             .|
 Worm   530 TGFFGQQDQMSTDIFGNSFDPN--------FSQDYAQDDYNDYMKQPKNE-------------DF 573

  Fly   556 EDMACKLKIAELHRDKAKQEAQEWKERYDLAQIQLN-LPAELRDLSIQKLKQLQSKL 611
            ..::.|.:..|......:|:|..|:.|::...::.| |.||..:| :.:::|::.::
 Worm   574 NSLSDKCQYLEESLKHTRQQADMWRMRFEGEFMEKNRLLAERSNL-LGQIEQMKHQM 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unk	NP_001303430.1	zf-CCCH	273..299	CDD:279036	20/25 (80%)
		FhaB	<311..548	CDD:225751	59/274 (22%)
		zf-C3HC4_3	626..671	CDD:290631
unk-1	NP_001263959.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167496
Domainoid	1	1.000	70	1.000	Domainoid score	I6231
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D316647at33208
OrthoFinder	1	1.000	-	-		FOG0003517
OrthoInspector	1	1.000	-	-		oto19739
orthoMCL	1	0.900	-	-		OOG6_105234
Panther	1	1.100	-	-	LDO	PTHR14493
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1211
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.850