Protein Alignment hh and grd-9

DIOPT Version :10

• Sequence 1: NP_001034065.1
• Gene: hh / 42737
• FlyBaseID: FBgn0004644
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_504535.2
• Gene: grd-9 / 191663
• WormBaseID: WBGene00001698
• Length: 588
• Species: Caenorhabditis elegans
• Alignment Length: 293
• Identity: 54/293 - (18%)
• Similarity: 89/293 - (30%)
• Gaps: 96/293 - (32%)

  Fly    90 GLGRHRARNLY--------------------PLVLKQTIPNLSEYTNSASGPLEGVIRRDSPKFK 134
            |:..:|:||.|                    .:..|.:..:.||....|........|:...|.|
 Worm   253 GVNNYRSRNSYGTNNRKHGRNGKKGKSSKMCKMCRKLSEEDESEEKEMACDLCSKSRRKGKKKGK 317

  Fly   135 DLVPNYNRDILFRDEEGTGADRLMSKRCKEKLNVLAYSVMNEWPGIRLLVTESWDEDYHHGQESL 199
            .|            .:|....|..|.:..|..:....|:..|..|     ||::..|..:|.:..
 Worm   318 SL------------RDGMVGGRRKSSKSSEDSDDHDDSMEGEGGG-----TENFTNDDENGADDY 365

  Fly   200 HYEGRAVTIATS-------------DRDQSKYGMLARL-----------------AVEAGFDWVS 234
            ..:|.:.||..:             .:.|:|   |.|:                 |.|.|.|
 Worm   366 EDDGESTTIKPNAVSQPTILDFVERSKQQNK---LMRIPVYRGKKLEAESNGTSGAYEDGDD--- 424

  Fly   235 YVSRRHIYCSVKSDSSISSHVHG---------------CFTPESTALLESGVRKPLGELSIGDRV 284
              :..|.....:..|..||::..               .:.|:.|..|::....|.|.:...
 Worm   425 --NGEHNREEEEESSQYSSNIRDMEQPTKYSSKPNVKYSYPPKDTLPLQTCFHNPSGYVCCN--- 484

  Fly   285 LSMTANGQAVYSEV---ILFMDRNLEQMQNFVQ 314
            |.:....::.|.||   ..|...||:.:.|.||
 Worm   485 LELNNVVESTYKEVRELPNFNPCNLQLIANKVQ 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hh	NP_001034065.1	HH_signal	85..243	CDD:460055	36/202 (18%)
		Hint	254..465	CDD:460051	15/79 (19%)
grd-9	NP_504535.2	Ground-like	479..561	CDD:461200	11/42 (26%)