Protein Alignment hh and wrt-1

DIOPT Version :9

• Sequence 1: NP_001034065.1
• Gene: hh / 42737
• FlyBaseID: FBgn0004644
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_495579.3
• Gene: wrt-1 / 174223
• WormBaseID: WBGene00006947
• Length: 484
• Species: Caenorhabditis elegans
• Alignment Length: 352
• Identity: 84/352 - (23%)
• Similarity: 145/352 - (41%)
• Gaps: 92/352 - (26%)

  Fly   140 YNRDILFRDEEGTGADRLMSKRCKEKL----NVLAYSV----MNEWPGIRLLVTESWDEDYHHGQ 196
            |:...:.||...||.|.:.:.|   |:    ..:||.|    ||..|              :.|:
 Worm   152 YSGGEVLRDGRQTGFDAISNVR---KITSGDGTVAYEVTVTRMNCLP--------------NPGE 199

  Fly   197 ESLHYEGRAVTIATSDRDQSKYGMLARLAVEAGFDWVSYVSRRHIYC--------SVKSDSSIS- 252
            ||     ..|:. ...||      :.|:..:.|....|.|...||..        .|:|||.:|
 Worm   200 ES-----NEVSF-DIQRD------IGRILDKVGETAASGVQTNHIEADQRLSPSTDVQSDSYVSP 252

  Fly   253 --------------------------------SHVHGCFTPESTALLESGVRKPLGELSIGDRVL 285
                                            |.|..|||..|..:..:| .|.:.:||:||.|:
 Worm   253 TEADPQEPVEQFVQVGEQVVPVTSAGYYYPVASGVPACFTGNSKVMTPAG-EKSMADLSVGDMVM 316

  Fly   286 SMTANGQAVYSEVILFMDRNLEQMQNFVQLHTDGGAVLTVTPAHLVSVWQPESQKLTFVFADRIE 350
            :. ..|:..|:.|..::.|..:....|::|.|:.||::.:||.|.:......::::..|:|:.:.
 Worm   317 TY-EYGKMTYTRVASWLHRLPDTKAAFIKLTTEQGAIIDMTPQHFIYKANCVTEEMELVYAEDMT 380

  Fly   351 EKNQVLVRDVETGELRPQRVVKVGSVRSKGVVAPLTREGTIVVNSVAASCYAVINSQSLAHWGL- 414
            ..:.::|::.|  :|....:.:..:....||.||:|..|.::|:.|.|||:.|:.:.:|:|..|
 Worm   381 IGDCLMVKENE--KLVMTTISEKSTFYETGVYAPMTETGDLIVDDVYASCHNVVKANTLSHTFLN 443

  Fly   415 ------APMR-LLSTLE--AWLPAKEQ 432
                  ..|| :|.:||  ..|||..:
 Worm   444 FATSVQQKMRSVLGSLEETGHLPATSE 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hh	NP_001034065.1	HH_signal	99..243	CDD:279432	26/110 (24%)
		Hint	254..465	CDD:279426	52/189 (28%)
		Hint	258..400	CDD:238035	37/141 (26%)
wrt-1	NP_495579.3	Hint	290..428	CDD:238035	37/141 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1169356at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14084
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820