Protein Alignment hh and dhh

DIOPT Version :9

• Sequence 1: NP_001034065.1
• Gene: hh / 42737
• FlyBaseID: FBgn0004644
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_001090638.1
• Gene: dhh / 100036603
• XenbaseID: XB-GENE-483465
• Length: 396
• Species: Xenopus tropicalis
• Alignment Length: 404
• Identity: 190/404 - (47%)
• Similarity: 254/404 - (62%)
• Gaps: 22/404 - (5%)

  Fly    64 LTSLVALLLIVLPMVFSPAHSCGPGRG-LGRHR-ARNLYPLVLKQTIPNLSEYTNSASGPLEGVI 126
            ||..|...|:::|:.     .|||||| :||.| .|.|.||..||.:||:.|.|..|||..||.|
 Frog     7 LTLAVCCWLLLVPVC-----CCGPGRGPVGRRRYMRKLVPLRYKQFVPNVPEKTLGASGKSEGKI 66

  Fly   127 RRDSPKFKDLVPNYNRDILFRDEEGTGADRLMSKRCKEKLNVLAYSVMNEWPGIRLLVTESWDED 191
            ||.|.:|.:||||||.||:|:|||.|||||||::|||:::|.||.||||.|||::|.|||.||||
 Frog    67 RRGSERFIELVPNYNPDIIFKDEENTGADRLMTERCKDRVNALAISVMNMWPGVKLRVTEGWDED 131

  Fly   192 YHHGQESLHYEGRAVTIATSDRDQSKYGMLARLAVEAGFDWVSYVSRRHIYCSVKSDSSISSHVH 256
            .||..:||||||||:.|.|||||:||||||||||||||||||.|.|:.||:.|||:|:|:.....
 Frog   132 GHHAHDSLHYEGRALDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHVSVKADNSLGVRSG 196

  Fly   257 GCFTPESTALLESGVRKPLGELSIGDRVLSMTANGQAVYSEVILFMDRNLEQMQNFVQLHTDG-G 320
            |||...:..::.||.:|.|.||.:||.|.:....||.:.|.|:||:.|:|.:...||.:..:| .
 Frog   197 GCFPGTAMVMMASGEKKSLSELQLGDTVFTTDETGQLIPSVVLLFLHRDLYKTATFVLIEAEGHT 261

  Fly   321 AVLTVTPAHLVSVWQPESQKLTFVFADRIEEKNQVLVRDVETGELRPQRVVKVGSVRSKGVVAPL 385
            :.|.|||.||:.:.:..|......||.|::..:.|.:. |...:|:|.:||:|......||.||:
 Frog   262 SKLLVTPNHLLFIKRSLSAGFLPTFAYRVQIGDLVQIY-VNGTQLQPSKVVRVSVEEQTGVYAPM 325

  Fly   386 TREGTIVVNSVAASCYAVINSQSLAHWGLAPMRLLSTLEAWLPAKEQLHSSPKVVSSAQQQNGIH 450
            |..||::|:.|..||||.:.|.:|||..|||:||...:.:.||             .....:|:|
 Frog   326 TEHGTLLVDGVLTSCYATVESHTLAHASLAPLRLFKGIASMLP-------------DLDLSDGVH 377

  Fly   451 WYANALYKVKDYVL 464
            ||.:.||.:..|||
 Frog   378 WYCHILYLLAKYVL 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hh	NP_001034065.1	HH_signal	99..243	CDD:279432	97/143 (68%)
		Hint	254..465	CDD:279426	73/212 (34%)
		Hint	258..400	CDD:238035	48/142 (34%)
dhh	NP_001090638.1	HH_signal	23..184	CDD:366456	107/160 (67%)
		Hint	187..391	CDD:366452	73/217 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	233	1.000	Domainoid score	I2340
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	354	1.000	Inparanoid score	I2196
OMA	1	1.010	-	-		QHG50028
OrthoDB	1	1.010	-	-		D1169356at2759
OrthoFinder	1	1.000	-	-		FOG0001612
OrthoInspector	1	1.000	-	-		otm49069
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1177
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.980