DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31365 and ZNF45

DIOPT Version :9

Sequence 1:NP_732827.1 Gene:CG31365 / 42736 FlyBaseID:FBgn0051365 Length:639 Species:Drosophila melanogaster
Sequence 2:NP_003416.1 Gene:ZNF45 / 7596 HGNCID:13111 Length:682 Species:Homo sapiens


Alignment Length:381 Identity:93/381 - (24%)
Similarity:162/381 - (42%) Gaps:91/381 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   311 EDFREINMVGSDVVHTDNG--------EIYIINSASSEDQNQDSTPEFDQDNGITSYNIKEDGEI 367
            |:||.:..||..  .|.:|        :::::..|:            .:||...:.|:||...:
Human    39 ENFRNVVSVGHQ--STPDGLPQLEREEKLWMMKMAT------------QRDNSSGAKNLKEMETL 89

  Fly   368 QFSGEKPEEIEDVVVFNLGEEISQEQQVFSFHENVIIVEKEQNDRDEQTPLKRK------RSSEL 426
            |..|.:....|::....:.::|::|  :..:.::|:.:::.....:::..|..|      :||.|
Human    90 QEVGLRYLPHEELFCSQIWQQITRE--LIKYQDSVVNIQRTGCQLEKRDDLHYKDEGFSNQSSHL 152

  Fly   427 VFKQESSCPQPKTGRITDTVKSF-------------------QCHLCPVAFPTQKLLTRH----- 467
            ...:..:..:|..|.  ..||||                   :|..|..||.....|..|     
Human   153 QVHRVHTGEKPYKGE--HCVKSFSWSSHLQINQRAHAGEKPYKCEKCDNAFRRFSSLQAHQRVHS 215

  Fly   468 ------------------HNTHIKGLKSGKGGTLKCPSCALQLSCASSLKRHMIIHTGLKPFKCS 514
                              |..|.:.:.:|: ...|...|...:..:|..:..:|:|||.||:||.
Human   216 RAKSYTNDASYRSFSQRSHLPHHQRVPTGE-NPYKYEECGRNVGKSSHCQAPLIVHTGEKPYKCE 279

  Fly   515 ECELSFSQREVLKRHMDTHTGVKRHQCPQCSSCFAQKSNLQQHIGRVHMGNSRTHKCHLCHRSFN 579
            ||.:.||||..|:.|:..|||.|.::|.:|...|:.:|.||.| .|:|.| .:.:||:.|.:||:
Human   280 ECGVGFSQRSYLQVHLKVHTGKKPYKCEECGKSFSWRSRLQAH-ERIHTG-EKPYKCNACGKSFS 342

  Fly   580 HVSGLSRHLVTHAGVM-FSCKQCGRQFNDRSAVQRHVTTMHKVKNKLTDYISETNE 634
            :.|.|:.|...|.|.. :.|::||:.|:..|.:|.|             .||.|.|
Human   343 YSSHLNIHCRIHTGEKPYKCEECGKGFSVGSHLQAH-------------QISHTGE 385

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31365NP_732827.1 zf-AD 13..86 CDD:214871
vATP-synt_E 109..>244 CDD:304907
RRF <161..222 CDD:294170
zf-C2H2_8 454..530 CDD:292531 26/98 (27%)
C2H2 Zn finger 485..505 CDD:275368 3/19 (16%)
zf-H2C2_2 497..522 CDD:290200 11/24 (46%)
C2H2 Zn finger 513..533 CDD:275368 9/19 (47%)
zf-H2C2_2 526..550 CDD:290200 9/23 (39%)
C2H2 Zn finger 541..562 CDD:275368 8/20 (40%)
C2H2 Zn finger 571..591 CDD:275368 7/19 (37%)
C2H2 Zn finger 598..617 CDD:275368 7/18 (39%)
ZNF45NP_003416.1 KRAB 8..67 CDD:214630 7/29 (24%)
KRAB 8..47 CDD:279668 3/7 (43%)
C2H2 Zn finger 166..186 CDD:275368 5/21 (24%)
COG5048 190..602 CDD:227381 63/212 (30%)
C2H2 Zn finger 194..214 CDD:275368 6/19 (32%)
C2H2 Zn finger 251..270 CDD:275368 3/18 (17%)
C2H2 Zn finger 278..298 CDD:275368 9/19 (47%)
zf-H2C2_2 290..314 CDD:290200 8/23 (35%)
C2H2 Zn finger 306..326 CDD:275368 8/20 (40%)
zf-H2C2_2 319..343 CDD:290200 11/25 (44%)
C2H2 Zn finger 334..354 CDD:275368 7/19 (37%)
zf-H2C2_2 346..370 CDD:290200 7/23 (30%)
C2H2 Zn finger 362..382 CDD:275368 8/32 (25%)
zf-H2C2_2 374..397 CDD:290200 6/25 (24%)
C2H2 Zn finger 390..410 CDD:275368
zf-H2C2_2 402..427 CDD:290200
C2H2 Zn finger 418..438 CDD:275368
zf-H2C2_2 430..455 CDD:290200
C2H2 Zn finger 446..466 CDD:275368
zf-H2C2_2 458..483 CDD:290200
C2H2 Zn finger 474..494 CDD:275368
zf-H2C2_2 486..511 CDD:290200
C2H2 Zn finger 502..522 CDD:275368
zf-H2C2_2 514..538 CDD:290200
C2H2 Zn finger 530..550 CDD:275368
zf-H2C2_2 543..565 CDD:290200
C2H2 Zn finger 558..578 CDD:275368
zf-H2C2_2 570..595 CDD:290200
zf-C2H2 584..606 CDD:278523
C2H2 Zn finger 586..606 CDD:275368
zf-H2C2_2 598..622 CDD:290200
C2H2 Zn finger 614..634 CDD:275368
zf-H2C2_2 626..650 CDD:290200
C2H2 Zn finger 642..662 CDD:275368
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 662..682
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24377
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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