DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31365 and Zbtb7c

DIOPT Version :9

Sequence 1:	NP_732827.1	Gene:	CG31365 / 42736	FlyBaseID:	FBgn0051365	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_001120847.1	Gene:	Zbtb7c / 679155	RGDID:	1591841	Length:	619	Species:	Rattus norvegicus

Alignment Length:	403	Identity:	90/403 - (22%)
Similarity:	142/403 - (35%)	Gaps:	131/403 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   316 INMVGSDVVHTDNG----EIYII------------NSASSEDQNQDSTPEFDQDNGITSYNIKED 364
            :.:..|:|.|..|.    ||..|            |....:|:.::...|.|.|         ||
  Rat    97 LTITASNVKHILNAARMLEIQCIVNVCLEIMEPGGNVGEEDDKEEEDDDEDDDD---------ED 152

  Fly   365 GEIQFSGEKPEEIEDVVVFNLGEEISQEQQV---FSFHENVIIVEKEQNDRDEQTP--------- 417
            .|.:...|:.||.:|...|...|.:...|.:   .|..:...:.||:.:|.....|
  Rat   153 DEEEEEEEEEEEEDDTEDFADQENLPDPQDINCPQSPSKTDCLTEKDYSDTPRDFPDSFQPESPG 217

  Fly   418 ---LKRKRSSELVFKQ----ESSCPQPKTGRITDTVKSFQCHLCPVAF------PTQKLLTRHHN 469
               :.|..|.|.:.::    ::|.|..:.. ::.....|..||.|..|      |.|.:.:...:
  Rat   218 HLGVIRDFSIESLLRENLYPKASIPDRRPS-LSPFAPEFFPHLWPGDFGAFAQLPEQPMDSGPLD 281

  Fly   470 THIKGLKSGK---------------------------GGTL------------------------ 483
            ..||..|..:                           ||.|
  Rat   282 LVIKDRKIKEEEKEELAPPPPPPFSSDFFKDMFPDLPGGPLGPIKAENDYGAYLNFLSATHLGSL 346

  Fly   484 ------------------KCPSCALQLSCASSLKRHMIIHTGLKPFKCSECELSFSQREVLKRHM 530
                              :||.|...:..|..|.|||..|||.||:.||.||:.|::::.||.||
  Rat   347 FPPWPLVEERKLKPKASQQCPICHKVIMGAGKLPRHMRTHTGEKPYMCSICEVRFTRQDKLKIHM 411

  Fly   531 DTHTGVKRHQCPQCSSCFAQKSNLQQHIGRVHMGNSRTHKCHLCHRSFNHVSGLSRHLVTHAGVM 595
            ..|||.:.:.|..|::.|....:|:.|: |:|.| .|.::|..|::||.....|.||:...
  Rat   412 RKHTGERPYLCIHCNAKFVHNYDLKNHM-RIHTG-VRPYQCEFCYKSFTRSDHLHRHIKRQ---- 470

  Fly   596 FSCKQC----GRQ 604
             ||:..    ||:
  Rat   471 -SCRMARPRRGRK 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31365	NP_732827.1	zf-AD	13..86	CDD:214871
		vATP-synt_E	109..>244	CDD:304907
		RRF	<161..222	CDD:294170
		zf-C2H2_8	454..530	CDD:292531	30/150 (20%)
		C2H2 Zn finger	485..505	CDD:275368	8/19 (42%)
		zf-H2C2_2	497..522	CDD:290200	14/24 (58%)
		C2H2 Zn finger	513..533	CDD:275368	9/19 (47%)
		zf-H2C2_2	526..550	CDD:290200	10/23 (43%)
		C2H2 Zn finger	541..562	CDD:275368	6/20 (30%)
		C2H2 Zn finger	571..591	CDD:275368	7/19 (37%)
		C2H2 Zn finger	598..617	CDD:275368	3/11 (27%)
Zbtb7c	NP_001120847.1	BTB_POZ_ZBTB7C_ZBTB36	9..128	CDD:349637	7/30 (23%)
		C2H2 Zn finger	366..386	CDD:275368	8/19 (42%)
		SFP1	<380..468	CDD:227516	36/89 (40%)
		C2H2 Zn finger	394..414	CDD:275368	9/19 (47%)
		C2H2 Zn finger	422..442	CDD:275368	6/20 (30%)
		C2H2 Zn finger	450..468	CDD:275368	7/17 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000