DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31365 and CG4936

DIOPT Version :9

Sequence 1:	NP_732827.1	Gene:	CG31365 / 42736	FlyBaseID:	FBgn0051365	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_650862.1	Gene:	CG4936 / 42393	FlyBaseID:	FBgn0038768	Length:	521	Species:	Drosophila melanogaster

Alignment Length:	633	Identity:	139/633 - (21%)
Similarity:	240/633 - (37%)	Gaps:	171/633 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AQPSYPDLAT----LCRLCLKEHQDAYAIFDEDDTQLSIPVRLMACVALDAKATDTLPKRICQEC 63
            |.|:....:|    :||:||::.::..|....||::..:...:..|..:..|..|..|.:||::|
  Fly     8 ASPAAAATSTQKWIVCRVCLQQPKEPMASIFNDDSEKDLTHMIRECGGVPIKQFDHYPDKICEKC 72

  Fly    64 RYQLEKSFLFRQRCQWAEKKLRKHIRLLGLGKR------SRVFSKDPDDYDEDELEFEDSIAFIE 122
            ...|:.:|.||:.||.:...||:.:..:.:.:|      |...:|...|.|.||.|.|..   .:
  Fly    73 FKVLKMAFKFRETCQRSYGHLRQFVGPVEVEQRPPEKKGSETATKLEPDVDPDEAEQEPE---HD 134

  Fly   123 VQDKVRKLEDEKWRE--DFKEEQAAEMHKRLVKSRLELRAKLTTELRKELAEEVRSEVRKE--LA 183
            .:|:...|::..:.|  |..|.|....|.       |:...:..||.|:....|::|..:|  :.
  Fly   135 EEDEDVDLDESHYAEADDAAETQGGVFHD-------EIEDGILVELEKDRIVHVKNEQVEEDGII 192

  Fly   184 EEVRSQVRDDLRNEVSED--IRKEQLAMLLGELEVYLTEKKAGRWESLDGSEPETKPQVKEDASP 246
            ||| ..|.:....::..|  ...|.....|.||...:        |.||..|.:   |:.|.|..
  Fly   193 EEV-YDVYETYEGDLIPDQGYDHEMADQALSELSAEI--------EYLDQVEHD---QLTESAHE 245

  Fly   247 SRSKTKALPKRRPSLVDANLKATEARKDAKEEEFILGCNTDPANNSDVNIDGLELDEE--VPAES 309
            ..::           ||.|         :.||||:      |:.:...:|......:.  .|..|
  Fly   246 DDAE-----------VDLN---------STEEEFV------PSKSVRASIHARNATKRRVNPRRS 284

  Fly   310 GEDFREINMVGSDVVHTDNGEIYIINSASSEDQNQDSTPEFDQDNGITSYNIKEDGEIQFSGEKP 374
            ......:.:..|....||.|....:...:|             |:..:..:||.:.:|
  Fly   285 ATSTASVAVESSTSKTTDRGNPLKVRRGNS-------------DSAGSKMSIKSEKDI------- 329

  Fly   375 EEIEDVVVFNLGEEISQEQQVFSFHENVIIVEKEQNDRDEQTPLKRKRSSELVFKQESSCPQPKT 439
                     ::||.::::      |..:                |.|...:::...:
  Fly   330 ---------SIGEVLARK------HSGI----------------KTKGGHKILLGDK-------- 355

  Fly   440 GRITDTVKSFQ--CHLCPVAFPTQKLLTRHHNTHIKGLKSGKGGTLKCPSCALQLSCASSLKRHM 502
                   |.|:  |.:|...:|:|..||.    |||
  Fly   356 -------KEFKYICDVCGNMYPSQSRLTE----HIK----------------------------- 380

  Fly   503 IIHTGLKPFKCSECELSFSQREVLKRHMDTHTGVKRHQCPQCSSCFAQKSNLQQHIGRVHMGNSR 567
             :|:|:||.:|..|...|:|.:.|.|||:||||.:.::|..|.:.||..|...:| .|:|. |.|
  Fly   381 -VHSGVKPHECEICGHCFAQAQQLARHMNTHTGNRPYKCSYCPAAFADLSTRNKH-HRIHT-NER 442

  Fly   568 THKCHLCHRSFNHVSGLSRHLVTHAGVM-FSCKQCGRQFNDRSAVQRH 614
            .::|.:||::|.:.:.|..|.:.|.|.. ..|..||:.|.....::.|
  Fly   443 PYECDVCHKTFTYTNTLKFHKMIHTGEKPHVCDVCGKGFPQAYKLRNH 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31365	NP_732827.1	zf-AD	13..86	CDD:214871	21/72 (29%)
		vATP-synt_E	109..>244	CDD:304907	33/140 (24%)
		RRF	<161..222	CDD:294170	15/64 (23%)
		zf-C2H2_8	454..530	CDD:292531	18/75 (24%)
		C2H2 Zn finger	485..505	CDD:275368	0/19 (0%)
		zf-H2C2_2	497..522	CDD:290200	7/24 (29%)
		C2H2 Zn finger	513..533	CDD:275368	8/19 (42%)
		zf-H2C2_2	526..550	CDD:290200	11/23 (48%)
		C2H2 Zn finger	541..562	CDD:275368	7/20 (35%)
		C2H2 Zn finger	571..591	CDD:275368	6/19 (32%)
		C2H2 Zn finger	598..617	CDD:275368	5/17 (29%)
CG4936	NP_650862.1	zf-AD	22..95	CDD:214871	21/72 (29%)
		C2H2 Zn finger	362..382	CDD:275368	9/53 (17%)
		zf-H2C2_2	375..399	CDD:290200	12/57 (21%)
		COG5048	386..>447	CDD:227381	24/62 (39%)
		C2H2 Zn finger	390..410	CDD:275368	8/19 (42%)
		zf-H2C2_2	403..426	CDD:290200	10/22 (45%)
		C2H2 Zn finger	418..438	CDD:275368	7/20 (35%)
		zf-H2C2_2	432..455	CDD:290200	9/24 (38%)
		C2H2 Zn finger	446..466	CDD:275368	6/19 (32%)
		zf-H2C2_2	459..481	CDD:290200	7/21 (33%)
		C2H2 Zn finger	474..494	CDD:275368	5/17 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	0	0.000