DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31365 and CG4424

DIOPT Version :9

Sequence 1:	NP_732827.1	Gene:	CG31365 / 42736	FlyBaseID:	FBgn0051365	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster

Alignment Length:	395	Identity:	90/395 - (22%)
Similarity:	135/395 - (34%)	Gaps:	122/395 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 SLVD--ANLKATEARKDAKEE----EFILGCNTDPANNSDVNIDGLELDEEVPAESGEDFREINM 318
            ||.|  .:|...:.|..||||    ...|.|..           .|.|        ...||:|..
  Fly    38 SLCDKIESLSGIQIRATAKEEVLPTRICLRCKA-----------FLTL--------AHKFRQICQ 83

  Fly   319 VGSDVVHTDNGEIYIINSASSE-------DQNQDSTPEFDQDNGITSYNIKEDGEIQFSGEKPEE 376
            ..::.:..     |:|..|..:       .|.:.|||.                  ....|:.|.
  Fly    84 RSNEFLRE-----YVIKDAVEQGVVKEVVQQTRPSTPP------------------PIETEQLEP 125

  Fly   377 IEDVVVFNLGEEISQEQQVFSFHENVIIVEKEQNDRDEQT---PLKRKRSSELV-------FKQE 431
            .||.|:         |:.|:|..:.:           |:|   |.:::|.:.|.       :...
  Fly   126 PEDEVL---------EEGVWSTEDPI-----------EETPHGPAEKERPTVLTVEMLPAPYPPP 170

  Fly   432 SSCPQP-KTGRITDTVKSFQCHLCPVAFPTQKLLTRHHNTHIKGLKSGKGGTLKCPSCALQLSCA 495
            :|.|.| ..|.:..  |...|.:|...:|.:..|..|...|      ......:|..|.......
  Fly   171 ASTPPPAPAGAVKG--KLHVCAICGNGYPRKSTLDTHMRRH------NDERPYECEICHKSFHVN 227

  Fly   496 SSLKRHMIIHTGLKPFKCSECELSFSQREVLKRHMDTHTGVKRHQCPQCSSCFAQKSNLQQHIGR 560
            ..||||:..|||.||:.|..|:.:|:.|..|.:|..||...:.:.|..|...|...|.|:.|. :
  Fly   228 YQLKRHIRQHTGAKPYTCQYCQRNFADRTSLVKHERTHRNERPYACKTCGKKFTYASVLKMHY-K 291

  Fly   561 VHMGNSRTHKCHLCHRSFNHVSGLSRHLVTHAGVMFSCKQCGRQFNDRSAVQRHVTTMHKVKNKL 625
            .|.| .:.|.|.||::||..:..|..||.|                     |:|:.     ..:|
  Fly   292 THTG-EKPHICQLCNKSFARIHNLVAHLQT---------------------QQHIN-----DPRL 329

  Fly   626 TDYIS 630
            |.|:|
  Fly   330 TAYLS 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31365	NP_732827.1	zf-AD	13..86	CDD:214871
		vATP-synt_E	109..>244	CDD:304907
		RRF	<161..222	CDD:294170
		zf-C2H2_8	454..530	CDD:292531	21/75 (28%)
		C2H2 Zn finger	485..505	CDD:275368	6/19 (32%)
		zf-H2C2_2	497..522	CDD:290200	12/24 (50%)
		C2H2 Zn finger	513..533	CDD:275368	6/19 (32%)
		zf-H2C2_2	526..550	CDD:290200	7/23 (30%)
		C2H2 Zn finger	541..562	CDD:275368	6/20 (30%)
		C2H2 Zn finger	571..591	CDD:275368	8/19 (42%)
		C2H2 Zn finger	598..617	CDD:275368	2/18 (11%)
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071	16/77 (21%)
		C2H2 Zn finger	189..209	CDD:275368	5/19 (26%)
		DUF45	<204..281	CDD:302795	23/82 (28%)
		COG5048	210..>345	CDD:227381	43/153 (28%)
		C2H2 Zn finger	217..237	CDD:275368	6/19 (32%)
		C2H2 Zn finger	245..265	CDD:275368	6/19 (32%)
		zf-H2C2_2	257..282	CDD:290200	7/24 (29%)
		C2H2 Zn finger	273..293	CDD:275368	6/20 (30%)
		zf-H2C2_2	286..310	CDD:290200	10/25 (40%)
		C2H2 Zn finger	301..320	CDD:275368	8/18 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050