DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31365 and CG17803

DIOPT Version :9

Sequence 1:	NP_732827.1	Gene:	CG31365 / 42736	FlyBaseID:	FBgn0051365	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_001303488.1	Gene:	CG17803 / 42141	FlyBaseID:	FBgn0038547	Length:	587	Species:	Drosophila melanogaster

Alignment Length:	647	Identity:	129/647 - (19%)
Similarity:	203/647 - (31%)	Gaps:	240/647 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 PDLATLCRLC---LKEHQDAYAIFDEDDTQLSIPVRLMACVALDAKATDTLPKRICQECRYQLEK 69
            |..|:.||.|   :..|:||..::|..:..|...::::..|.:. :....||..||..|:..:.|
  Fly    80 PPPASKCRTCFRIISRHEDAQDLYDRVNIALLHHIKVITGVWIQ-QGVKELPHHICSTCQETVNK 143

  Fly    70 SFLFRQRCQWAEKKLRKHIRLLGLGKRSRVFSKDPDDYDEDELEFEDSIAFIEVQDKVRKLEDEK 134
            |..||.:||..:||||                :..:.|:            |::.|
  Fly   144 SMEFRAKCQQVDKKLR----------------QTTEKYN------------IQICD--------- 171

  Fly   135 WREDFKEEQAAEMHKRLVKSRLELRAKLTTELRKELAEEVRSEVRKELAEEVRSQVRDDLRNEVS 199
                                                 ||:.||:...|.||...|.:..:.   .
  Fly   172 -------------------------------------EEMESELENVLYEESAQQAKGVVG---L 196

  Fly   200 EDIRKEQLAMLLGELEVYLTEKKAGRWESLDGSEPETKPQVKEDASPSRSKTKALPKRRPSLVDA 264
            ||...|.|                          |:::..:.||..|
  Fly   197 EDFSSELL--------------------------PDSEGVLDEDDFP------------------ 217

  Fly   265 NLKATEARKDAKEEEFILGCNTDPANNSDVNIDGLELDEEVPAESGEDFREINMVGSDVVHTDNG 329
                    .||:..:|.|            :.|.|:||.    ::.:||
  Fly   218 --------LDAEPTQFSL------------SEDELDLDR----DTEKDF---------------- 242

  Fly   330 EIYIINSASSEDQNQDSTPEFDQDNGITSYNIKEDGEIQFSGEKPEEIEDVVVFNLGEEISQEQQ 394
                     :.:||                  |...|| .|..|.:..|::...:.|.::.:
  Fly   243 ---------ALEQN------------------KSCNEI-ISIRKCKTKEEIGKVDHGAKVYK--- 276

  Fly   395 VFSFHENVIIVEKEQNDRDEQTPLKRKRSSELVFK-QESSCPQPKTGRITDTVK----SFQCHLC 454
                     :|..|.|...|..|   |.|..|..| |....|:.|..|..:.::    ::.|..|
  Fly   277 ---------VVLGEYNSLKETAP---KYSLSLPKKPQLRVSPEEKNRRRRERIQAKPLNYVCDKC 329

  Fly   455 PVAFPTQKLLTRHHNTHIKGLKSGKGGTLKCPSCALQLSCASSLKRHM-IIHTGLKPFKCSECEL 518
            ...|..:..|..|.      |:..:....:||.|..:.....:...|: .:|.|..||.|:.|..
  Fly   330 GHTFRQRSQLQMHL------LRHNRAKNFECPECPKKFYDLYTRNIHVRALHKGEHPFPCNHCNE 388

  Fly   519 SFSQREVLKRH-MDTH--------------TGVKRHQCPQCSSCFAQKSNLQQHIGRVHMGNSRT 568
            ||:......|| .|.|              .|..||.|.||:..:..|..|..|: ..|.| ||.
  Fly   389 SFANASSRHRHERDVHGAGNRIRTRVKSKEEGSSRHYCTQCTKSYTSKKGLVLHM-NFHNG-SRP 451

  Fly   569 HKCHLCHRSFNHVSGLSRHLVTHAGVMFSCKQCGRQFNDRSAVQRHV---TTMHKVKNKLTD 627
            .:|.:|...|...|.:.||...|......|..|.:.|..||.:.:|.   |.||..:.::.|
  Fly   452 FQCKICQMKFADPSAMKRHQALHDKFPIRCDICLKGFLLRSQLTKHQDVHTGMHPHRCEICD 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31365	NP_732827.1	zf-AD	13..86	CDD:214871	23/75 (31%)
		vATP-synt_E	109..>244	CDD:304907	16/134 (12%)
		RRF	<161..222	CDD:294170	12/60 (20%)
		zf-C2H2_8	454..530	CDD:292531	19/77 (25%)
		C2H2 Zn finger	485..505	CDD:275368	4/20 (20%)
		zf-H2C2_2	497..522	CDD:290200	9/25 (36%)
		C2H2 Zn finger	513..533	CDD:275368	7/20 (35%)
		zf-H2C2_2	526..550	CDD:290200	10/38 (26%)
		C2H2 Zn finger	541..562	CDD:275368	6/20 (30%)
		C2H2 Zn finger	571..591	CDD:275368	6/19 (32%)
		C2H2 Zn finger	598..617	CDD:275368	6/21 (29%)
CG17803	NP_001303488.1	zf-AD	86..160	CDD:214871	24/90 (27%)
		COG5048	<323..528	CDD:227381	52/199 (26%)
		zf-C2H2	324..346	CDD:278523	6/27 (22%)
		C2H2 Zn finger	326..346	CDD:275368	6/25 (24%)
		C2H2 Zn finger	354..375	CDD:275368	4/20 (20%)
		C2H2 Zn finger	383..401	CDD:275368	6/17 (35%)
		C2H2 Zn finger	426..446	CDD:275368	6/20 (30%)
		C2H2 Zn finger	454..474	CDD:275368	6/19 (32%)
		C2H2 Zn finger	481..501	CDD:275368	6/19 (32%)
		C2H2 Zn finger	509..528	CDD:275368	1/5 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050