DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31365 and pad

DIOPT Version :9

Sequence 1:	NP_732827.1	Gene:	CG31365 / 42736	FlyBaseID:	FBgn0051365	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_650534.2	Gene:	pad / 41981	FlyBaseID:	FBgn0038418	Length:	924	Species:	Drosophila melanogaster

Alignment Length:	868	Identity:	147/868 - (16%)
Similarity:	285/868 - (32%)	Gaps:	262/868 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LCRLCLKEHQDAYAIFDEDDTQLSIPVRLMACVALDAKATDTLPKRICQECRYQLEKSFLFRQRC 77
            |||:|.........|:..:....::..:::.|::|.....|.|||.:|.:|...:|:....|..|
  Fly    16 LCRICTDSSDHKTNIYSPEGRAKNLSQKILECLSLQIDEKDRLPKVVCAQCVQLVEQIHGLRATC 80

  Fly    78 QWAEKKLRKHIRLLGLGKRSRVFSKDPDDYDEDELEFEDS------------------IAFIEVQ 124
            :.::..|...:.:.......:::.:|..|.....|....|                  |..:.:|
  Fly    81 RNSQTMLNNCLNIRPAPSSDKLYIRDAVDETGKSLSVAQSAPPVPNGAQQSGNLLNSIIQAVNMQ 145

  Fly   125 DKVR------------------------KLEDEKWREDF---------------------KEEQA 144
            .:.:                        |.|.:...|:|                     |.:|.
  Fly   146 PQQQYTITMDNGVQQQQQQHQAMPEVQIKSERQTALEEFIRLKPDIKITPLGKKEPISPAKPQQQ 210

  Fly   145 AEMHKRLV-----KSRLELRAKLTTELRKELAEEVRSEVRKELAEEVRSQVRDDLRNEVSEDIRK 204
            ..:..:.|     .::|:|:.:|..:| :.|.::::....::..:::.:|::...:..|::|...
  Fly   211 HSLQSQTVTPTINPTQLQLQPQLGDQL-QPLWQQIQQLQLQQQLQQLTNQLQATTQYSVAQDDTS 274

  Fly   205 EQLAMLLGELEVYLTEKKAGRWES----LDGSEPETKPQVKEDAS--------PSRSKTKAL--- 254
            ........:|...|:...|.::.:    ..||:|:.:.|:...:.        |::::..|.
  Fly   275 SSGDSKKPKLNFVLSSPTAPQFTTSMPQFGGSQPQIQLQLMPGSGGVTSAGTVPAQTQLNAAALL 339

  Fly   255 -----PKRRPSLVDAN---LKATEARKDAKEEEFILGCNTD----PANNSD--------VNIDG- 298
                 |:...:|:..|   |..| .|.:..:::.:...:|.    |.....        ...||
  Fly   340 SSLAGPQSTTNLLSPNKCFLPIT-IRDENSDQQIVAHIDTKNLVLPTTYQVQMKLQPQLATADGQ 403

  Fly   299 -------------LELDEEVPAESGEDFR--------------------------EINMVGSDVV 324
                         |:|..:.....|..|:                          ...::.|...
  Fly   404 PIMQLTPTSIPATLQLTPQTLGNPGSAFQGTTVTQNQFLAPQQPLTQLPNTAQVTSQQIIRSPHT 468

  Fly   325 HTDNGEIYIIN----------SASSEDQNQDSTPEFDQ------------------DNGITSYNI 361
            .|.|.::.|.|          ..||:......||...|                  .||.::...
  Fly   469 STTNSQLVIRNVTNIPPTPTTPTSSKKAPTFKTPSPKQKPMPSPKSKTTVGPSSGGSNGTSTNEF 533

  Fly   362 KEDGEIQFSGEKPEEIEDVVVFNLGEEISQEQ--------------------QVFSFHENVIIVE 406
            |.    ..:..||:           .::.|:|                    |..|.:..:..|.
  Fly   534 KR----LITQTKPQ-----------PQVKQQQTAGLSASGAPTATSANQAAMQRLSSNTTITKVP 583

  Fly   407 KEQNDRDEQTPLKRKRSSELVFKQ-------------------ESSCPQPKTGRITDTVKSF-QC 451
            |:........|........::.||                   .::.|.|.:..|..:|.:. |.
  Fly   584 KQPASLPAPAPTSNPAKLPMLNKQNITISRISMQTAPKAQSKPSTTSPTPASQPIPVSVPALSQA 648

  Fly   452 HLCPVAFPTQKLLTR-HHNTHIKGLK----------------SGKGGT-----------LKCPSC 488
            ...|:|...:|::.: ..|....|.|                .|:..|           |.||:|
  Fly   649 QPPPLAAQHKKIVRKPPENQDTSGQKVKAARPPQQILPSPQQEGQNATHSGSEAPTTSGLICPTC 713

  Fly   489 ALQLSCASSLKRHMIIHTGLKPFKCSE--CELSFSQREVLKRHMDTHTGVKRHQCPQCSSCFAQK 551
            ..:......|.:|:.:|.||:||||||  |:.:||::|.|.||:.:|:|.|.:.|..|...|::|
  Fly   714 KREFKKKEHLTQHVKLHAGLRPFKCSEEGCDKTFSRKEHLSRHLVSHSGQKMYTCEVCKKPFSRK 778

  Fly   552 SNLQQHIGRVHMGNS--RTHKCHLCHRSFNHVSGLSRHLVTHAGVMFSCKQCGRQFNDRSA-VQR 613
            .||.:| .|:|...|  ..:.|.:|:::|.......:|...|..:.......|...:..:| ...
  Fly   779 DNLNKH-RRIHTQTSTETLYCCDVCNKNFATKLHYEKHREMHKKIRPESAAPGATASPAAAPALT 842

  Fly   614 HVTTMHKVKNKLTDYISETNEFQ 636
            ||.:..:|.||....|.:....|
  Fly   843 HVRSNGQVPNKAVFEIKQERSAQ 865

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31365	NP_732827.1	zf-AD	13..86	CDD:214871	17/72 (24%)
		vATP-synt_E	109..>244	CDD:304907	26/206 (13%)
		RRF	<161..222	CDD:294170	8/60 (13%)
		zf-C2H2_8	454..530	CDD:292531	29/105 (28%)
		C2H2 Zn finger	485..505	CDD:275368	5/19 (26%)
		zf-H2C2_2	497..522	CDD:290200	13/26 (50%)
		C2H2 Zn finger	513..533	CDD:275368	10/21 (48%)
		zf-H2C2_2	526..550	CDD:290200	9/23 (39%)
		C2H2 Zn finger	541..562	CDD:275368	8/20 (40%)
		C2H2 Zn finger	571..591	CDD:275368	4/19 (21%)
		C2H2 Zn finger	598..617	CDD:275368	4/19 (21%)
pad	NP_650534.2	zf-AD	16..87	CDD:214871	16/70 (23%)
		C2H2 Zn finger	710..730	CDD:275368	5/19 (26%)
		zf-C2H2	736..760	CDD:278523	12/23 (52%)
		C2H2 Zn finger	738..760	CDD:275368	10/21 (48%)
		zf-H2C2_2	752..777	CDD:290200	9/24 (38%)
		zf-C2H2	766..788	CDD:278523	8/22 (36%)
		C2H2 Zn finger	768..788	CDD:275368	8/20 (40%)
		zf-H2C2_2	780..808	CDD:290200	9/28 (32%)
		C2H2 Zn finger	799..819	CDD:275368	4/19 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24377
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010